Plugpen XP Injection

Brand Name Plugpen XP Injection
Salt Composition Meropenem (1000mg) + Sulbactam (500mg)
Strength 1000mg + 500mg
Product Form Injection
Pack 1 Injection in 1 Vial
Storage Store at room temperature (10-30°C)
Category Antibiotic
Country of Origin India
Manufacturer Samarth Life Sciences Pvt Ltd
Manufacturer/Marketer AddressSamarth Life Sciences Pvt Ltd, Samarth House, 168, Bangur Nagar, Off Link Road, Near Ayappa Temple & Kallol kali Temple, Goregaon(W), Mumbai - 400 090
-25%
Plugpen XP Injection, Meropenem 1000mg, Sulbactam 500mg, Price, Uses, Side Effects - Drugcarts watermark
M.R.P : Rs.799.00       Price : Rs.599.25

You Save : Rs.199.75    Inclusive of all taxes

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1 Injection in 1 Vial

Availability : In Stock

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    Medical Description of Plugpen XP Injection

    Plugpen XP injection contains Meropenam 1000mg and Sulbactam 500mg used to treat severe bacterial infections such as Bacterial meningitis, Pneumonia, Skin, and skin structure infections, and Intra-abdominal infections. Mainly this infection affects the lungs, skin, and skin structures, abdomen, and brain. Meropenem is an antibiotic that kills the bacteria that cause infections. Sulbactam is a β lactamase inhibitor. It should be given with antibiotic, which works by inhibiting the β lactamase enzyme (destroys the action of antibiotics) produced by bacteria.  The combination of this medicine helps to fight against microbes and also prevents the growth of bacteria. This medicine is not used for common flu and cold symptoms that occur due to viral infections. This medicine is commonly prescribed for cough and colds caused by bacterial and parasitic infections.


    Plugpen XP Injection Uses

    It is used in the treatment of the following conditions as Bacterial meningitis, Pneumonia, Skin, and skin structure infections, and Intra-abdominal infections.


    Plugpen XP Injection Benefits

    Bacterial infections:     

    Bacterial infection occurs when bacteria enter your body and start multiplying which may cause tissue damage and make you sick. Mostly it is caused by Staphylococcus and Streptococcus organisms. The bacterial diseases are cholera, bacterial meningitis, tetanus, gonorrhea, pneumonia, and syphilis. Symptoms include fever, chills, and sweats, inflamed lymph nodes, headache, diarrhea, abdominal pain

    Bacterial meningitis

    Infection and inflammation to the meninges (in the brain) caused by bacteria called bacterial meningitis. This medicine is used to treat this bacterial infection.

    Pneumonia

    It is a lung infection that causes inflammation in the alveoli. It is usually caused by Streptococcus pneumonia. Symptoms include chest pain, fatigue, fever, sweating, nausea, vomiting, diarrhea, breathing difficulty, cough, and confusion

    Skin infection

    It is usually caused by bacteria, fungi, viruses, and parasites. Common skin infection includes cellulitis, impetigo. Symptoms include red skin, blisters, swelling, pain, red spots, and tenderness

    Intra-abdominal infections

    Bacteria causes infection to the inside of the abdomen called intra-abdominal infections such as peritonitis, pancreatitis, diverticulitis, cholecystitis, and cholangitis. This medicine is used to treat this bacterial infection.


    Plugpen XP Injection Indication

    Plugpen XP injection is prescribed in the following indications such Bacterial meningitis, Pneumonia, Skin, and skin structure infections, and Intra-abdominal infections


    Mechanism of action of Plugpen XP Injection

    Plugpen XP contains Meropenem is a Carbapenem antibiotic is used to treat bacterial infections. It blocks the bacterial cell wall synthesis which is essential for bacterial growth and also prevents the spreading of infections without making them resistant to further treatment. Sulbactam is a beta-lactamase inhibitor that produces its action by inhibiting the enzymes which are produced by the bacteria. This enzyme inactivates the effect of the antibiotic. The combination with Subactum helps to reduce the development of resistance and increase the action of Meropenem against bacteria.


    How Plugpen XP Injection works

    Plugpen XP contains Meropenem is a Carbapenem antibiotic is used to treat bacterial infections. It blocks the bacterial cell wall synthesis which is essential for bacterial growth and also prevents the spreading of infections without making them resistant to further treatment. Sulbactam is a beta-lactamase inhibitor that produces its action by inhibiting the enzymes which are produced by the bacteria. This enzyme inactivates the effect of the antibiotic. The combination with Subactum helps to reduce the development of resistance and increase the action of Meropenem against bacteria.


    Plugpen XP Injection Contraindication

    • Do not take this medicine if you are allergic to beta-lactam
    • Kindly avoid this medicine if you are having hepatic and renal impairment
    • Seizures are most commonly found in patients who are with CNS disorders
    • Thrombocytopenia is common in patients who are with renal disorders
    • The use of this medicine may cause toxic epidermal necrolysis, Stevens-Johson syndrome, dermatitis exfoliative.


    Plugpen XP Injection Side Effects

    • Swelling and redness occurs at the injection site
    • Fever 
    • Confusion
    • Diarrhea
    • Skin rashes
    • Seizures
    • Dark, or clay-colored stools
    • Decreased urine output
    • Fast heartbeat


    FAQs for Plugpen XP Injection

    • My friend has a history of epilepsy and she was on valproic acid while receiving treatment with Plugpen XP injection, but still, she had an episode of seizure may I why?

    Before initiating the treatment kindly consult with your doctor regarding the previous history of treatment. The use of this injection may interact with valproic acid and may decrease its effect. This will be the reason behind the recent episode of seizure. Kindly consult with your doctor

    • Is Plugpen XP injection can be used for any type of bacterial infection?

    No, it is effective against some bacteria like Staphylococcus aureus, Streptococcus aureus, Streptococcus pneumonia, S. pyogenes, S.viridans.

    • For how long will I need to take Plugpen XP injection?

    The duration of this injection depends upon your condition of infection and according to the type of infection


    Precautions and general warning of Plugpen XP Injection

    Alcohol

    Consuming alcohol while receiving this medication is considered cautious it may produce any harmful effects. Kindly consult with your doctor.

    Driving or operating machinery

    No, it is not clear that the use of this medicine will affect your ability to drive. Kindly consult with your doctor.

    Pregnancy

    The use of this medicine is considered safe during pregnancy because it does not produce any harmful effects on the fetus. Kindly consult with your doctor

    Breast Feeding

    The use of this medicine is considered safe during breastfeeding because it does not excrete via breastmilk. Kindly consult with your doctor

    Kidney Problem

    The Injection should be used with caution in patients with renal impairment. The use of this medicine required dose modification. Kindly consult with your doctor.

    Liver Disease

    Less information is available regarding the use of this medicine in liver disease patients. Kindly consult with the doctor.


    How to Take Plugpen XP Injection

    This injection comes in a powder form with sterile water, before using this injection mix both the content and shake well before use. It is injected by a health care professional in doctor clinics, hospitals. Use the injection as prescribed by your doctor. Do not discontinue the medicine when you feel better kindly consult together with your doctor.


    Use of Plugpen XP Injection in Adult

    It is considered to be safe to use this medicine in an adult patient if the medicine is prescribed by a doctor. Kindly consult with your doctor.


    Use of Plugpen XP Injection in children

    Plugpen XP injection is not prescribed in children who are below 3 years old. Kindly consult with your doctor.


    Use of Plugpen XP Injection in Elderly Patients

    Plugpen XP injection should be used with caution in patients with an elderly age group, which leads to developing further medical problems, leads to worsening the patient's health conditions. Kindly consult with your doctor. Dose modification or replacement is required based on the medical conditions of the patient.


    Other general warnings

    • Therapy should be administered with caution if you have a history of penicillin allergy and gastrointestinal disease
    • Long-term use may cause bacterial or fungal overgrowth
    • The use of this medicine in renal failure patients may cause thrombocytopenia
    • The use of this medicine can cause Clostridium difficile-associated diarrhea
    • It produces limited effect against anaerobes


    Talk to your doctor if

    • You have a history of gastrointestinal disease
    • You have diarrhea during the treatment
    • You have any sudden allergic effects like rashes, itching, inflammation, dizziness, and difficulty in breathing
    • You are not responding to the treatment


    General instructions

    Plugpen XP injection contains Meropenam 1000mg and Sulbactam 500mg used to treat severe bacterial infections such as Bacterial meningitis, Pneumonia, Skin, and skin structure infections, and Intra-abdominal infections. Mainly this infection affects the lungs, skin, and skin structures, abdomen, and brain. Meropenem is an antibiotic that kills the bacteria that cause infections. Sulbactam is a β lactamase inhibitor. It should be given with antibiotic, which works by inhibiting the β lactamase enzyme (destroys the action of antibiotics) produced by bacteria.  The combination of this medicine helps to fight against microbes and also prevents the growth of bacteria.


    Drug Interaction of Plugpen XP Injection

    Drug-Drug Interaction

    BCG vaccine live

    The use of this medicine is contraindicated because the use of medicine decreases the effect of the BCG vaccine live by pharmacodynamic antagonism

    Cholera vaccine

    Use alternative medicine, because the use of the cholera vaccine with antibiotics may activate the vaccine strain. So, avoid receiving this combination of medicines before 14 days of vaccination

    Estradiol:

    Therapy should be administered with caution because the use of meropenem will decrease the effect of estradiol by altering the intestinal flora and it also lowers the risk of contraceptive failure

    Probenecid

    It is a uricosuric used to treat chronic gout and gouty arthritis. This medicine alters the action of probenecid. . Kindly consult with your doctor

    Tramadol

    It is an opioid analgesic used to treat pain after surgery or serious injury. This medicine alters the action of tramadol. Kindly consult with your doctor

    Drug-Food Interaction

    The food may increase the effect of the medicine in your body so it is advised to take this Injection with food to increase the absorption

    Drug-Disease Interaction

    Central nervous system disorders

    It should be used with caution in patients with seizures, other central nervous system abnormalities, or fits. It causes hallucinations, anxiety, confusion, and restlessness. Kindly inform your doctor if you have experienced any of these effects

     Colitis

    This medicine kills the good helpful bacteria in your stomach or intestine and causes diarrhea. This drug should be used caution in patients with gastrointestinal disease, especially colitis (swelling of the colon inner lining). It leads to worsening the patient's health conditions.

    Kidney disease

    It should be used with caution in a patient with renal impairment or kidney disease. Then it leads to the risk of kidney damage. Inform your doctor, and then take for a better life. Based on your conditions, dose adjustment is needed.


    Over Dose

    Take the medicine as directed by the doctor don’t overdose on the medicine. If you have taken an overdose of this medicine immediately meet the doctor and rush to the nearby hospital.


    Missed Dose

    Take the medicine as directed by the doctor. Do not skip the medicine, if you forgot to take the medicine or missed the dose. It is almost time for your next dose, skip the missed dose and go back to your regular schedule. Don’t take the extra dose take the regular dose immediately. Don’t use the two-dose at one time (Double Dose).


    Storage and Disposal

    • Stored at 10-30°C room temperature.
    • Protect from light and heat.
    • Keep away from children and pets. Otherwise, it becomes toxic to them.
    • Disposed of properly in a suitable bag.


    Fast Tag

    Plugpen XP Injection contains Meropenem is a Carbapenem antibiotic is used to treat bacterial infections. It blocks the bacterial cell wall synthesis which is essential for bacterial growth and also prevents the spreading of infections without making them resistant to further treatment. Sulbactam is a beta-lactamase inhibitor that produces its action by inhibiting the enzymes which are produced by the bacteria. This enzyme inactivates the effect of the antibiotic. The combination with Subactum helps to reduce the development of resistance and increase the action of Meropenem against bacteria.

    This medicine is not used for common flu and cold symptoms. And not treat viral infections. This medicine is commonly prescribed for cough and colds caused by bacterial and parasitic infections.

    This medicine is contraindicated to allergic symptoms such as skin rash, itching, swelling, and breathing difficulties.