Brand Name Pregabid-D 75/30 Capsule DR
Salt Composition

Pregabalin (75mg) + Duloxetine (30mg)

Strength 75mg + 30mg
Product Form Capsule
Pack 10 Capsule(s) in Strip
Storage Store below 30°C
Category

Anticonvulsant and Antidepressant

SubCategory

Neuropathic pain

Country of Origin India
Manufacturer

Intas Pharmaceuticals Ltd

Manufacturer/Marketer Address Intas Pharmaceuticals Ltd,Chinubhai Centre, Off. Nehru Bridge, Ashram Road, Ahmedabad - 380009. Gujarat. India.
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M.R.P : Rs.239.00       Price : Rs.191.20

You Save : Rs.47.80    Inclusive of all taxes

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10 Capsule(s) in Strip

Availability : In Stock

  Online Payment Only

  Non Returnable Read More



    Medical Description of Pregabid-D 75/30 Capsule DR

    Pregabid-D 75/30 Capsule DR contains Pregabalin 75mg and Duloxetine 30mg is a combination of anticonvulsants and antidepressants used in the treatment of neuropathic pain. The combination of this medicine produces its action by controlling the activity of the calcium channel in your nerve cells and decreasing pain and it also increases the level of chemical messengers in your brain which helps to maintain mental balance.


    Pregabid-D 75/30 Capsule DR Uses

    It is used in the treatment of neuropathic pain


    Pregabid-D 75/30 Capsule DR Benefits

    Neuropathic pain

    It is often described as shooting or burning pain. It is usually caused by alcoholism, diabetes, facial nerve problems, HIV infection, stroke, Parkinson's disease, multiple sclerosis, and shingles. The symptoms include shooting, burning, stabbing, electric shock-like pain, tingling, numbness, or pins and needles


    Pregabid-D 75/30 Capsule DR Indication

    The Pregabid-D 75/30 Capsule DR is prescribed for the following indications as neuropathic pain


    Mechanism of action of Pregabid-D 75/30 Capsule DR

    Pregabid-D 75/30 Capsule DR contains Pregabalin 75mg and Duloxetine 30mg is a combination of anticonvulsants and antidepressants. Pregabalin is an antiepileptic medication that produces its action by decreasing the abnormal electrical activity in your brain. It also treats nerve pain by interfering with the pain signals which is present in your brain and treating damaged nerves.

    Duloxetine is an antidepressant that produces its action by increasing the level of chemical messengers, serotonin, and noradrenaline in your brain that helps to maintain your mental balance and inhibit the movement of pain signals in your brain.


    How Pregabid-D 75/30 Capsule DR works

    Pregabid-D 75/30 Capsule DR contains Pregabalin 75mg and Duloxetine 30mg is a combination of anticonvulsants and antidepressants. Pregabalin is an antiepileptic medication that produces its action by decreasing the abnormal electrical activity in your brain. It also treats nerve pain by interfering with the pain signals which is present in your brain and treating damaged nerves.

    Duloxetine is an antidepressant that produces its action by increasing the level of chemical messengers, serotonin, and noradrenaline in your brain that helps to maintain your mental balance and inhibit the movement of pain signals in your brain.


    Pregabid-D 75/30 Capsule DR Contraindication

    • Do not take this medicine if you are allergic to Pregabalin and Duloxetine
    • It is contraindicated to use this medicine along with monoamine oxidase inhibitors


    Pregabid-D 75/30 Capsule DR Side Effects

    • Dizziness
    • Sedation
    • Peripheral edema
    • Fatigue
    • Weight gain
    • Blurred vision
    • Headache
    • Dry mouth
    • Constipation
    • Diarrhea


    FAQs for Pregabid-D 75/30 Capsule DR

    • For how long should I take the Pregabid-D 75/30 Capsule DR?

    The duration of the treatment is as short as possible. Do not stop the medicines suddenly when you feel better it may produce withdrawal syndrome. So your doctor may gradually decrease the medicines to avoid withdrawal side effects.

    • Is the Pregabid-D 75/30 Capsule DR addictive?

    Yes, the people who are taking this medicine for a long period may lead to addiction. And also people with a history of alcoholism and drug abuse are more prone to become addicted.

    • Is the Pregabid-D 75/30 Capsule DR safe?

    Yes, the use of this medicine is considered safe if you use this medicine as per the dose and duration advice by your doctor.


    Precautions and general warning of Pregabid-D 75/30 Capsule DR

    Alcohol

    It is considered unsafe to consume alcohol while taking this medication. Kindly consult with your doctor

    Driving or operating machinery

    It is considered unsafe to drive while you are receiving this medicine because the use of this medicine may affect your ability to drive. Kindly consult with your doctor.

    Pregnancy

    It is considered unsafe during pregnancy because it may produce harmful effects on the fetus. Kindly consult with your doctor.

    Breast Feeding

    It is considered unsafe to use this medicine during breastfeeding because it may excrete via breast milk. Kindly consult with your doctor

    Kidney Problem

    This medicine should be used with caution in patients with kidney impairment. The use of this medicine required dose modification. Kindly consult with your doctor.

    Liver Disease

    This medicine should be used with caution in patients with liver impairment. The use of this medicine required dose modification. Kindly consult with your doctor.


    How to Take Pregabid-D 75/30 Capsule DR

    The capsule is taken orally with or without food. You should not chew, cut or crush the capsule. Take this medicine as per the dose and duration advised by your doctor. Follow the direction mentioned within the label if you probably did not understand the appliance kindly ask your doctor or pharmacist to elucidate in detail. Do not withdraw the medicine when you feel better kindly complete the course of treatment to avoid reoccurrence.


    Use of Pregabid-D 75/30 Capsule DR in Adult

    It is considered to be safe to use this medicine in an adult patient if the medicine is prescribed by a doctor. Kindly consult with your doctor.


    Use of Pregabid-D 75/30 Capsule DR in children

    It is considered unsafe to use this medicine in children who are below 18 years old. Kindly consult with your doctor.


    Use of Pregabid-D 75/30 Capsule DR in Elderly Patients

    Pregabid-D 75/30 Capsule DR should be used with caution in patients in an elderly age group, which leads to developing further medical problems, leading to worsening the patient's health conditions. Kindly consult with your doctor. Dose modification or replacement is required based on the medical conditions of the patient.


    Other general warnings

    • The use of this medicine may cause hepatotoxicity, severe skin reactions, hyponatremia, and urinary retention.
    • Bone fractures were reported while you are receiving this medicine
    • Therapy should be administered with caution in patients with hypertension, narrow-angle glaucoma, kidney impairment, and seizure disorders
    • The use of this medicine may increase the risk of mydriasis, blood pressure
    • Headache, dizziness, nausea, diarrhea, vomiting, insomnia, and fatigue were reported


    Talk to your doctor if

    • You have a history of gastrointestinal disease
    • You are not responding to the treatment
    • You have experienced any allergic reactions like rashes and itching
    • You are suffering from depression
    • You have watery diarrhea, stomach pain, and fever


    General instructions

    Pregabalin 75mg and Duloxetine 30mg are a combination of anticonvulsants and antidepressants used in the treatment of neuropathic pain. The combination of this medicine produces its action by controlling the activity of the calcium channel in your nerve cells and decreasing pain and it also increases the level of chemical messengers in your brain which helps to maintain mental balance.


    Drug Interaction of Pregabid-D 75/30 Capsule DR

    Drug-Drug Interaction

    Benazepril + Pregabalin

    Coadministration increases the risk of developing angioedema of the face, mouth, and neck. Angioedema may result in respiratory compromise.

    Clobazam + Pregabalin

    Concomitant administration can increase the potential for CNS effect. The combination of these drugs may increase sedation or respiratory depression.

    Lurasidone + Pregabalin

    The combination of this drug may increase the toxicity of the other because it increases the risk of CNS depressant effect

    Orlistat + Pregabalin

    Orlistat decreases the level of pregabalin by inhibiting GI absorption. Therapy should be administered with caution because it combination of this drug may increase the risk of convulsions

    Rasagiline + Duloxetine

    A combination of these drugs increases the serotonin level. The use of this drug is contraindicated if you have taken the drug within 14 days of administration of monoamine oxidase inhibitors

    Phenelzine + Duloxetine

    The combination of these drugs will increase the serotonin level. Use alternative drug

    Alfentanil + Duloxetine

    A combination of these drugs increases serotonin levels. Using alternative drugs may cause serotonin syndrome

    Dolesetron + Duloxetine

    A combination of these drugs either increases the toxicity of others by serotonin levels. Use alternative drug

    Captopril + Duloxetine

    Duloxetine increases the effect of captopril by affecting hepatic enzyme metabolism. Therapy should be administered with caution.

    Drug-Food Interaction

    The use of alcohol may increase nervous system side effects such as dizziness, drowsiness, and difficulty in concentrating. Do not stop this medicine without consulting with your doctor

    Drug-Disease Interaction

    Angioedema

    Therapy should be administered with caution in a patient with angioedema because the use of pregabalin may increase the risk of developing angioedema

    Creatinine Kinase Elevations

    Therapy should be administered with caution in a patient with elevated creatine kinase levels because the use of pregabalin may be associated with creatine kinase elevations

    Peripheral edema

    The use of pregabalin is contraindicated in patients with congestive heart failure because the use of pregabalin may increase the risk of peripheral edema

    Drug dependence

    Therapy should be administered with caution in patients with a history of alcohol or substance abuse because the use of an anxiolytic agent can cause dependence and abuse. Dose reduction is necessary.

    Depression

    Therapy should be administered with caution in adult and pediatric patients with depression because they may have suicidal thoughts. Patients should be monitored closely for any changes in their behavior or suicidal thoughts. Do not discontinue the treatment without consulting with the doctor it may worsen the symptoms.

    Renal dysfunction

    The drug is metabolized in the kidney and excreted through urine. Therapy should be administered with caution in a patient with renal impairment because there is no information regarding the pharmacokinetics of milnacipran in a patient with severe renal impairment

     Liver diseases

    Therapy should be administered with caution in patients with liver impairment because there is an increase in plasma concentration of serotonin and norepinephrine reuptake inhibitor and prolonged half-life in a patient with hepatic impairment.

    Mania

    Selective serotonin and norepinephrine reuptake inhibitors may cause hypomania so therapy should be administered with caution in a patient with a history of bipolar disorder. Before initiating the treatment closely monitor the patient for bipolar disorder.


    Over Dose

    Take the medicine as directed by the doctor don’t overdose on the medicine. If you have taken an overdose on this medicine immediately meet the doctor and rush to the nearby hospital.


    Missed Dose

    Take the medicine as directed by the doctor. Do not skip the medicine, if you forgot to take the medicine or missed the dose. It is almost time for your next dose, skip the missed dose and go back to your regular schedule. Don’t take the extra dose take the regular dose immediately. Don’t use the two-dose at one time (Double Dose).


    Storage and Disposal

    • Stored at 10-30°C room temperature.
    • Protect from light and heat.
    • Keep away from children and pets. Otherwise, it becomes toxic to them.
    • Disposed of properly in a suitable bag.


    Fast Tag

    • Pregabid-D 75/30 Capsule DR contains Pregabalin 75mg and Duloxetine 30mg is a combination of anticonvulsants and antidepressants used in the treatment of neuropathic pain.
    • The combination of this medicine produces its action by controlling the activity of the calcium channel in your nerve cells and decreasing pain and it also increases the level of chemical messengers in your brain which helps to maintain mental balance.
    • Avoid consuming alcohol while you are receiving this medicine because it may cause dizziness
    • Inform your doctor if you have experienced suicidal thoughts
    • Do not stop taking this medicine without consulting with a doctor