Raltegravir Mcneil Argus

Brand Name Raltegravir Mcneil Argus
Salt Composition

Raltegravir (400mg)

Strength 400mg
Product Form Tablet
Pack 60 Tablet(s) in 1 Bottle
Storage Store below 30°C
Category

HIV

SubCategory

HIV

Country of Origin India
Manufacturer

Mcneil & Argus Pharmaceuticals Ltd

Manufacturer/Marketer Address Mcneil & Argus Pharmaceuticals Ltd,100-rampur sarsehri road, ambala cantt-133001 india
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M.R.P : Rs.8680.00       Price : Rs.6944.00

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60 Tablet(s) in 1 Bottle

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    Medical Description of Raltegravir Mcneil Argus

    Raltegravir Mcneil Argus contains its active substance called Raltegravir. Raltegravir is an antiretroviral medicine used in the treatment of HIV-1 infection. It is a HIV-1 integrase inhibitor. It is used in combination with other antiretrovirals to treat HIV. It is also used in treatment as post exposure for occupational exposure to HIV therapy.


    Raltegravir Mcneil Argus Uses

    Raltegravir Mcneil Argus is used to treat adults and children above 2 years of age or weight class above 10 Kgs who are infected by HIV-1 infection. Raltegravir Mcneil Argus should be taken with other anti-HIV medications.


    Raltegravir Mcneil Argus Benefits

    Raltegravir Mcneil Argus contains its active substance called Raltegravir. Raltegravir Mcneil Argus is used to treat HIV-1 infection. Raltegravir Mcneil Argus is a HIV-1 integrase inhibitor. Raltegravir Mcneil Argus is not a cure for HIV infection, it helps manage and treat HIV. It improves immune system thus prevents co-infection and cancers. Raltegravir Mcneil Argus  is not recommended for use in children less than 2 years of age or weight lesser than 10 Kgs due to the increased risk of serious side effects.


    Raltegravir Mcneil Argus Indication

    Raltegravir Mcneil Argus is indicated in case of HIV-1 infection. Raltegravir Mcneil Argus is co-administered safely with other antiretrovirals for HIV. Raltegravir Mcneil Argus is indicated in ages above 2 years of age or weight above 10Kgs. Caution is used in the case of diagnosed phenylketonuria.


    Mechanism of action of Raltegravir Mcneil Argus

    Raltegravir Mcneil Argus contains its active substance called Raltegravir. Raltegravir is integrase inhibitor. Raltegravir acts as an inhibitor of HIV-1 catalytic activity. Thus inhibits the replication of virus. Thus, in combination with other antiretrovirals.


    How Raltegravir Mcneil Argus works

    Raltegravir Mcneil Argus is HIV-1 integrase inhibitor. Raltegravir Mcneil Argus inhibits the action of HIV-1 viruses’ catalytic action, thereby preventing the formation of mature virus particles. Thus, controls HIV infection and improves immunity.


    Raltegravir Mcneil Argus Contraindication

    • if you are allergic to Raltegravir Mcneil Argus.
    • if you have renal diseases like phenylketonuria
    • if you have mental disorders
    • if you are lactating
    • if you are pregnant
    • if you are diabetic
    • if you have liver diseases


    Raltegravir Mcneil Argus Side Effects

    Very common side effects that occur 1:10 patients: Rash, nausea, vomiting, abdominal pain, diarrhoea, somnolence

    common side effects that occur 1:100 patients: headache, insomnia, fatigue, dizziness, dyspepsia, and increased liver enzymes, Decreased levels of neutrophils

    uncommon side effects that occur 1:1000 patients: rash, hair loss, hematuria, jaundice, osteonecrosis, severe allergic reaction, lactic acidosis


    FAQs for Raltegravir Mcneil Argus

    • Is Raltegravir Mcneil Argus safe during pregnancy?

    No, taking Raltegravir Mcneil Argus during pregnancy is not recommended. Consult your physician.

    • Can Raltegravir Mcneil Argus be taken while breast feeding?

    No, taking Raltegravir Mcneil Argus is not recommended during breast feeding. Consult your physician.

    • Can Raltegravir Mcneil Argus be taken while alcohol consumption?

    The interaction is unknown but this medication causes side effects. Thus, consult your physician.

    • Can I take drive or operate heavy machineries while on Raltegravir Mcneil Argus?

    This medication causes side effects thus caution is used while driving or operating machineries.

    • Can Raltegravir Mcneil Argus be taken as a monotherapy for HIV?

    No, Raltegravir Mcneil Argus is used with other antiretrovirals that treat HIV infection


    Precautions and general warning of Raltegravir Mcneil Argus

    Alcohol

    Raltegravir Mcneil Argus generally causes side effects thus it is advised not to be taken with alcohol. For further queries, consult your physician.

    Driving or operating machinery

    It is preferred to drive or operate heavy machinery with caution as Raltegravir Mcneil Argus causes side effects. For further queries, consult your physician.

    Pregnancy

    The use of Raltegravir Mcneil Argus is not recommended during pregnancy.

    Breast Feeding

    The use of Raltegravir Mcneil Argus during breastfeeding is not recommended.

    Kidney Problem

    Like phenylketonuria – monitor function. For further queries, consult your physician.

    Liver Disease

    • Like hepatitis B or C
    • Monitor liver function before and during therapy, especially in patients with other


    How to Take Raltegravir Mcneil Argus

    Raltegravir Mcneil Argus is taken orally without food for best result.

    Raltegravir Mcneil Argus must be taken at the same time once a day as prescribed by your physician.

    Raltegravir Mcneil Argus is always taken with other antiretrovirals for treating HIV infection.

    After therapy has been initiated, do not take more or less of this drug than prescribed or stop taking it without your physicians’ approval. Skipping or changing your dose without approval may cause the amount of the virus to increase making the infection more difficult to treat, or worsen side effects.


    Use of Raltegravir Mcneil Argus in Adult

    • If you are pregnant or breastfeeding inform your physician as they are not advisable.
    • The recommended dosage of Raltegravir Mcneil Argus in HIV infection is 400mg taken orally twice per day
    • Raltegravir Mcneil Argus must be taken with other antiretrovirals as prescribed by the physician without fail. These drugs must be taken with or without food on a regular time basis.


    Use of Raltegravir Mcneil Argus in children

    Raltegravir Mcneil Argus is used in children above 2 years of age or 10 Kgs of weight

                    10 to 14 kgs – 75mg twice per day

                    14 to 20 kgs – 100mg twice per day

                    20 to 28 kgs – 150mg twice per day

                    28 to 40 – 200mg twice per day

                    >40 kgs – 300mg twice per day

    Raltegravir Mcneil Argus must be taken with other antiretrovirals as prescribed by the physician without fail. These drugs must be taken with or without food on a regular time basis.


    Use of Raltegravir Mcneil Argus in Elderly Patients

    Raltegravir Mcneil Argus has only been used in few patients 65 years or older. Dosage and usage are similar to adults. Discuss with your physician before usage.


    Other general warnings

    • Skin reactions - It can be mild to severe like Stevens-Johnson Syndrome and toxic epidermal necrolysis.
    • New onset diabetes mellitus or hyperglycemia – Monitor blood glucose and insulin levels.
    • Immune reconstitution syndrome
    • Lactic acidosis
    • Rhabdomyolysis and myopathy


    Talk to your doctor if

    • If you have any allergy
    • If you have a liver problem
    • If you have a kidney problem
    • If you are diabetic
    • If you are pregnant or breastfeeding


    General instructions

    Raltegravir Mcneil Argus is taken orally with or without food as prescribed dosage at specific time regularly. It can be safely used in cases of HIV cases who are on a regime


    Drug Interaction of Raltegravir Mcneil Argus

    Drug-Drug Interaction

    • antacids containing calcium, magnesium, or aluminum
    • carbamazepine/ phenobarbital/ phenytoin
    • statins
    • etravirine
    • fenofibrate
    • gemfibrozil
    •  rifampin
    • tipranavir with ritonavir
    • zidovudine

    Drug-Food Interaction

    Raltegravir Mcneil Argus can be safely taken with any type of food, if doubts arise kindly refer to your physician. Raltegravir Mcneil Argus generally causes side effects thus it is advised not to be taken with alcohol. It is preferred to drive or operate heavy machinery with caution.


    Over Dose

    Contact your doctor, pharmacist or nurse immediately.


    Missed Dose

    • If you take once a day dosage, then the missed dosage if you notice within 12 hours. If it is more than 12 hours, then skip the dosage and take the next doses as usual.
    • If you take twice a day dosage, then the missed dosage if you notice within 6 hours. If it is more than 6 hours, then skip the dosage and take the next doses as usual.
    • Always take with other antiretrovirals Don’t take a double dose for a forgotten dose.


    Storage and Disposal

    • Keep the medication out of children’s reach
    • Keep the medication away from pets
    • Once expired dispose immediately
    • Store at 30?C


    Fast Tag

    • Raltegravir Mcneil Argus contains its active substance called Raltegravir.
    • It is an integrase inhibitor.
    • It is used to control and treat HIV infection
    • Do not use this medication while lactation period.
    • Don’t use this medication with liver disease and kidney diseases.
    • This medication doesn’t stop the spread of HIV infection from person to person thus use caution and precaution while sexual contact, needle injury etc.