Revolade 50mg Tablet

Brand Name Revolade 50mg Tablet
Salt Composition Eltrombopag (50mg)
Strength 50mg
Product Form Tablet
Pack 7 Tablet(s) in Strip
Storage Store at room temperature (10-30°C)
Category Anti-Cancer
Country of Origin India
Manufacturer Glaxo SmithKline Pharmaceuticals Ltd
Manufacturer/Marketer AddressGlaxo SmithKline Pharmaceuticals Ltd, Dr. Annie Besant Road, Mumbai - 400 030
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Revolade 50mg Tablet, Eltrombopag 50mg, price, uses, side effects - Drugcarts watermark
M.R.P : Rs.15194.00       Price : Rs.14434.30

You Save : Rs.759.70    Inclusive of all taxes

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7 Tablet(s) in Strip

Availability : In Stock


    Medical Description of Revolade 50mg Tablet

    Revolade 50mg Tablet contains Eltrombopag 50mg it’s an antineoplastic medication. It is a thrombopoietin receptor agonist. This tablet acts on hematopoietic growth factors and inhibits its function. This tablet is used in the treatment of thrombocytopenia and aplastic anemia. This medication is recommended for adults and children more than 1 year of age.


    Revolade 50mg Tablet Uses

    Revolade 50mg Tablet is used in the treatment of thrombocytopenia and aplastic anemia. It is used only in adults and children above age 1.


    Revolade 50mg Tablet Benefits

    Revolade 50mg Tablet is an antineoplastic, thrombopoietin receptor antagonist that inhibits the function of hematopoietic growth factors. This tablet is used in the treatment of aplastic anemia. This tablet is used in the treatment of thrombocytopenia which is immune-mediated or hepatitis C associated type. It can be used in patients above age 1.


    Revolade 50mg Tablet Indication

    Revolade 50mg Tablet is an antineoplastic, thrombopoietin receptor inhibitor. This tablet acts on hematopoietic growth factors and inhibits its growth functions. This tablet inhibits the multiplication or proliferation of abnormal cells by inhibiting signalling pathway required for proliferation.  This tablet is used in adults and children above age 1 in the treatment of

    • Chronic immune thrombocytopenia who has failed treatment with splenectomy, immunoglobulin and corticosteroids
    • Chronic hepatitis C associated thrombocytopenia treated with interferon-based treatment
    • Severe aplastic anemia treated with immunosuppressant


    Mechanism of action of Revolade 50mg Tablet

    Revolade 50mg (Eltrombopag 50mg) Tablet is an antineoplastic.  It is a thrombopoietin receptor antagonist. It competitively binds to the thrombopoietin receptor and inhibits the proliferation of megakaryocytes and platelet production. The decrease in proliferation causes effective treatment way for conditions related to thrombocytopenia and aplastic anemia.


    How Revolade 50mg Tablet works

    This tablet inhibits the proliferation of megakaryocytes and platelet production which is the function of thrombopoietin receptors. The decrease in proliferation causes effective treatment way for conditions related to thrombocytopenia of immune-mediated or hepatitis C mediated and aplastic anemia


    Revolade 50mg Tablet Contraindication

    Absolute contraindication:

    • if you are allergic to Revolade 50mg (Eltrombopag 50mg) Tablet or its constituents
    • if you are pregnant
    • if you are breastfeeding

    Relative contraindication:

    • if you have a hepatic disorder
    • if you have a haematological disorder
    • if you have a haemorrhagic disorder
    • if you have an ocular disorder


    Revolade 50mg Tablet Side Effects

    Common side effects that occur 1:10 patients: Anemia, Pyrexia, Fatigue, Headache, Nausea, Diarrhea, Decreased appetite, Influenza-like illness, Insomnia, Asthenia, Cough, Pruritus, Chills, Myalgia, Increased ALT/ AST, Increased blood bilirubin, upper respiratory tract infection, nasopharyngitis

    Uncommon side effects that occur 1:100 patients: Headache, Nausea, Cough, Abdominal pain, Oropharyngeal pain, Toothache, Vomiting, Urinary tract infection, Cataract, Rash, Pharyngitis, Rhinorrhea, Back pain, Influenza, Paresthesia, Alopecia, Peripheral edema, Skin discoloration including hyperpigmentation,

    Rare side effects that occur 1:1,000 patients: Anaphylactic shock, angioedema, urticaria, Stevens-Johnson Syndrome (SJS), hepatotoxicity


    FAQs for Revolade 50mg Tablet

    Is Revolade 50mg (Eltrombopag 50mg) Tablet safe during pregnancy?

    No, taking Revolade 50mg Tablet during pregnancy is not recommended thus inform your physician if you are pregnant or plan to get pregnant

    Can Revolade 50mg Tablet be taken while breastfeeding?

    No, in general, it is suggested that drugs and their metabolites can pass via breastfeeding thus it is suspected that Revolade 50mg Tablet can also pass via breastfeeding.

    Can Revolade 50mg Tablet be taken while alcohol consumption?

    The interaction is unknown but Revolade 50mg tablet causes side effects. Thus, consult your physician.

    Can I take a drive or operate heavy machineries while on Revolade 50mg Tablet?

    Revolade 50mg tablet causes side effects thus caution is used while driving or operating machineries.


    Precautions and general warning of Revolade 50mg Tablet

    Alcohol

    Alcohol intake  – Revolade 50mg Tablet causes side effects thus caution is required. consult your physician

    Driving or operating machinery

    Driving or operating heavy machinery – Revolade 50mg Tablet causes side effects thus caution is required. consult your physician

    Pregnancy

    Pregnancy - Causes embryo-fetal toxicity

    Breast Feeding

    Breastfeeding - causes side effects similar to adults

    Kidney Problem

    Consult your physician

    Liver Disease

    Hepatotoxicity – raise in enzymes


    How to Take Revolade 50mg Tablet

    This tablet is taken orally; It must be taken at the same time once a day as prescribed by your physician; It can be taken without food either 1 hr before or 2 hrs after food intake;

    Co-administrating supplement medications must be taken either 2 hrs before or 4 hrs after intake of this medication; It must be swallowed as a whole; Don’t chew or break this tablet.

    After therapy has been initiated, do not take more or less of this drug than prescribed or stop taking it without your physicians’ approval. Skipping or changing your dose without approval may cause adverse effects making the condition more difficult to treat, or worsen side effects.


    Use of Revolade 50mg Tablet in Adult

    If you are pregnant or breastfeeding inform your physician as they are not advisable.


    Use of Revolade 50mg Tablet in children

    This tablet is not recommended in children under 1 year of age


    Use of Revolade 50mg Tablet in Elderly Patients

    This tablet has only been used in few patients 65 years or older. Dosage and usage are similar to adults. Discuss with your physician before usage.


    Other general warnings

    • Allergic reactions - It can be mild hypersensitivity and angioedema to severe like Stevens-Johnson Syndrome and toxic epidermal necrolysis.
    • Hepatotoxicity – raise in enzymes
    • Thromboembolic events
    • Haematological events – anemia/platelet
    • Haemorrhagic events
    • Cataract
    • Bone marrow fibrosis
    • Progression of myelodysplastic syndrome
    • Pregnancy – causes embryo-fetal toxicity
    • Breastfeeding – causes side effects similar to adults
    • Alcohol intake or Driving or operating heavy machinery – Revolade 50mg Tablet causes side effects thus caution is required. consult your physician


    Talk to your doctor if

    If you have any allergy

    If you have a liver problem

    If you have bleeding disorder

    If you are pregnant or breastfeeding


    General instructions

    Revolade 50mg Tablet is taken orally as prescribed dosage at a specific time regularly on an empty stomach either 1 hr before or 2 hrs after food intake. If taken as an oral solution for children shake the bottle for 20sec before use.


    Drug Interaction of Revolade 50mg Tablet

    Drug-Drug Interaction

    Metabolism is decreased by Adenine, Melatonin, Tretinoin

    Serum concentration is decreased by calcium, Magnesium lactate, Zinc ascorbate

    Serum concentration is increased by folic acid

    Drug-Food Interaction

    This tablet must be taken without food on an empty stomach either 1 hr before or 2 hr after food, if doubts arise kindly refer to your physician. Revolade generally causes side effects thus it is advised not to be taken with alcohol. It is preferred to drive or operate heavy machinery with caution.

    Drug-Disease Interaction

    • Cardiac disorders – used with caution in heart arrythmia. Consult a physician before use
    • Hematological disorders – used with caution in bleeding disorders like thrombosis. Consult a physician before use
    • Bone disorders – used with caution in osteonecrosis. Consult a physician before use.
    • Liver disorders – used with caution in severe liver diseases. Consult a physician before use
    • Kidney disorders – used with caution in severe kidney diseases. Consult a physician before use
    • Respiratory disorders – used with caution in respiratory distress and interstitial lung disorder. Consult a physician before use


    Over Dose

    Overdosage of the tablet has less literature thus Contact your physician.


    Missed Dose

    You can take the missed dosage if you notice within 12 hours. If it is more than 12 hours, then skip the dosage and take the next doses as usual. Don’t take a double dose for a forgotten dose.


    Storage and Disposal

    Keep the medication out of children’s reach

    Keep the medication away from pets

    Once expired dispose immediately

    Store at room temperature


    Fast Tag

    Revolade 50mg Tablet is an antineoplastic medication

    Eltrombopag is a thrombopoietin receptor agonist

    This tablet is used to control and treat thrombocytopenia and aplastic anemia.

    Do not use this medication while pregnant and lactation period.

    Don’t use this medication with liver disease or renal diseases or cardiac disorders.