Revolade 50mg Tablet
Brand Name | Revolade 50mg Tablet |
Salt Composition |
Eltrombopag (50mg) |
Strength | 50mg |
Product Form | Tablet |
Pack | 7 Tablet(s) in Strip |
Storage | Store below 30°C |
Category |
Anti-Cancer |
SubCategory |
Bladder Cancer |
Country of Origin | India |
Manufacturer |
Glaxo SmithKline Pharmaceuticals Ltd |
Manufacturer/Marketer Address | Glaxo SmithKline Pharmaceuticals Ltd, Dr. Annie Besant Road, Mumbai - 400 030 |
You Save : Rs.759.70 Inclusive of all taxes
- Chronic immune thrombocytopenia who has failed treatment with splenectomy, immunoglobulin and corticosteroids
- Chronic hepatitis C associated thrombocytopenia treated with interferon-based treatment
- Severe aplastic anemia treated with immunosuppressant
- if you are allergic to Revolade 50mg (Eltrombopag 50mg) Tablet or its constituents
- if you are pregnant
- if you are breastfeeding
- if you have a hepatic disorder
- if you have a haematological disorder
- if you have a haemorrhagic disorder
- if you have an ocular disorder
- Allergic reactions - It can be mild hypersensitivity and angioedema to severe like Stevens-Johnson Syndrome and toxic epidermal necrolysis.
- Hepatotoxicity – raise in enzymes
- Thromboembolic events
- Haematological events – anemia/platelet
- Haemorrhagic events
- Cataract
- Bone marrow fibrosis
- Progression of myelodysplastic syndrome
- Pregnancy – causes embryo-fetal toxicity
- Breastfeeding – causes side effects similar to adults
- Alcohol intake or Driving or operating heavy machinery – Revolade 50mg Tablet causes side effects thus caution is required. consult your physician
- Cardiac disorders – used with caution in heart arrythmia. Consult a physician before use
- Hematological disorders – used with caution in bleeding disorders like thrombosis. Consult a physician before use
- Bone disorders – used with caution in osteonecrosis. Consult a physician before use.
- Liver disorders – used with caution in severe liver diseases. Consult a physician before use
- Kidney disorders – used with caution in severe kidney diseases. Consult a physician before use
- Respiratory disorders – used with caution in respiratory distress and interstitial lung disorder. Consult a physician before use
Medical Description of Revolade 50mg Tablet
Revolade 50mg Tablet contains Eltrombopag 50mg it’s an antineoplastic medication. It is a thrombopoietin receptor agonist. This tablet acts on hematopoietic growth factors and inhibits its function. This tablet is used in the treatment of thrombocytopenia and aplastic anemia. This medication is recommended for adults and children more than 1 year of age.
Revolade 50mg Tablet Uses
Revolade 50mg Tablet is used in the treatment of thrombocytopenia and aplastic anemia. It is used only in adults and children above age 1.
Revolade 50mg Tablet Benefits
Revolade 50mg Tablet is an antineoplastic, thrombopoietin receptor antagonist that inhibits the function of hematopoietic growth factors. This tablet is used in the treatment of aplastic anemia. This tablet is used in the treatment of thrombocytopenia which is immune-mediated or hepatitis C associated type. It can be used in patients above age 1.
Revolade 50mg Tablet Indication
Revolade 50mg Tablet is an antineoplastic, thrombopoietin receptor inhibitor. This tablet acts on hematopoietic growth factors and inhibits its growth functions. This tablet inhibits the multiplication or proliferation of abnormal cells by inhibiting signalling pathway required for proliferation. This tablet is used in adults and children above age 1 in the treatment of
Mechanism of action of Revolade 50mg Tablet
Revolade 50mg (Eltrombopag 50mg) Tablet is an antineoplastic. It is a thrombopoietin receptor antagonist. It competitively binds to the thrombopoietin receptor and inhibits the proliferation of megakaryocytes and platelet production. The decrease in proliferation causes effective treatment way for conditions related to thrombocytopenia and aplastic anemia.
How Revolade 50mg Tablet works
This tablet inhibits the proliferation of megakaryocytes and platelet production which is the function of thrombopoietin receptors. The decrease in proliferation causes effective treatment way for conditions related to thrombocytopenia of immune-mediated or hepatitis C mediated and aplastic anemia
Revolade 50mg Tablet Contraindication
Absolute contraindication:
Relative contraindication:
Revolade 50mg Tablet Side Effects
Common side effects that occur 1:10 patients: Anemia, Pyrexia, Fatigue, Headache, Nausea, Diarrhea, Decreased appetite, Influenza-like illness, Insomnia, Asthenia, Cough, Pruritus, Chills, Myalgia, Increased ALT/ AST, Increased blood bilirubin, upper respiratory tract infection, nasopharyngitis
Uncommon side effects that occur 1:100 patients: Headache, Nausea, Cough, Abdominal pain, Oropharyngeal pain, Toothache, Vomiting, Urinary tract infection, Cataract, Rash, Pharyngitis, Rhinorrhea, Back pain, Influenza, Paresthesia, Alopecia, Peripheral edema, Skin discoloration including hyperpigmentation,
Rare side effects that occur 1:1,000 patients: Anaphylactic shock, angioedema, urticaria, Stevens-Johnson Syndrome (SJS), hepatotoxicity
FAQs for Revolade 50mg Tablet
Is Revolade 50mg (Eltrombopag 50mg) Tablet safe during pregnancy?
No, taking Revolade 50mg Tablet during pregnancy is not recommended thus inform your physician if you are pregnant or plan to get pregnant
Can Revolade 50mg Tablet be taken while breastfeeding?
No, in general, it is suggested that drugs and their metabolites can pass via breastfeeding thus it is suspected that Revolade 50mg Tablet can also pass via breastfeeding.
Can Revolade 50mg Tablet be taken while alcohol consumption?
The interaction is unknown but Revolade 50mg tablet causes side effects. Thus, consult your physician.
Can I take a drive or operate heavy machineries while on Revolade 50mg Tablet?
Revolade 50mg tablet causes side effects thus caution is used while driving or operating machineries.
Precautions and general warning of Revolade 50mg Tablet
Alcohol
Alcohol intake – Revolade 50mg Tablet causes side effects thus caution is required. consult your physician
Driving or operating machinery
Driving or operating heavy machinery – Revolade 50mg Tablet causes side effects thus caution is required. consult your physician
Pregnancy
Pregnancy - Causes embryo-fetal toxicity
Breast Feeding
Breastfeeding - causes side effects similar to adults
Kidney Problem
Consult your physician
Liver Disease
Hepatotoxicity – raise in enzymes
How to Take Revolade 50mg Tablet
This tablet is taken orally; It must be taken at the same time once a day as prescribed by your physician; It can be taken without food either 1 hr before or 2 hrs after food intake;
Co-administrating supplement medications must be taken either 2 hrs before or 4 hrs after intake of this medication; It must be swallowed as a whole; Don’t chew or break this tablet.
After therapy has been initiated, do not take more or less of this drug than prescribed or stop taking it without your physicians’ approval. Skipping or changing your dose without approval may cause adverse effects making the condition more difficult to treat, or worsen side effects.
Use of Revolade 50mg Tablet in Adult
If you are pregnant or breastfeeding inform your physician as they are not advisable.
Use of Revolade 50mg Tablet in children
This tablet is not recommended in children under 1 year of age
Use of Revolade 50mg Tablet in Elderly Patients
This tablet has only been used in few patients 65 years or older. Dosage and usage are similar to adults. Discuss with your physician before usage.
Other general warnings
Talk to your doctor if
If you have any allergy
If you have a liver problem
If you have bleeding disorder
If you are pregnant or breastfeeding
General instructions
Revolade 50mg Tablet is taken orally as prescribed dosage at a specific time regularly on an empty stomach either 1 hr before or 2 hrs after food intake. If taken as an oral solution for children shake the bottle for 20sec before use.
Drug Interaction of Revolade 50mg Tablet
Drug-Drug Interaction
Metabolism is decreased by Adenine, Melatonin, Tretinoin
Serum concentration is decreased by calcium, Magnesium lactate, Zinc ascorbate
Serum concentration is increased by folic acid
Drug-Food Interaction
This tablet must be taken without food on an empty stomach either 1 hr before or 2 hr after food, if doubts arise kindly refer to your physician. Revolade generally causes side effects thus it is advised not to be taken with alcohol. It is preferred to drive or operate heavy machinery with caution.
Drug-Disease Interaction
Over Dose
Overdosage of the tablet has less literature thus Contact your physician.
Missed Dose
You can take the missed dosage if you notice within 12 hours. If it is more than 12 hours, then skip the dosage and take the next doses as usual. Don’t take a double dose for a forgotten dose.
Storage and Disposal
Keep the medication out of children’s reach
Keep the medication away from pets
Once expired dispose immediately
Store at room temperature
Fast Tag
Revolade 50mg Tablet is an antineoplastic medication
Eltrombopag is a thrombopoietin receptor agonist
This tablet is used to control and treat thrombocytopenia and aplastic anemia.
Do not use this medication while pregnant and lactation period.
Don’t use this medication with liver disease or renal diseases or cardiac disorders.