Rez-Q 600mg Injection

Rez-Q 600mg Injection contains Quinine Sulfate 600mg used to treat parasitic infections such as Malaria. Quinine Sulphate is an antimalarial drug, it is an alkaloid obtained from cinchona bark, results in interacting with certain substances which are required for the malarial parasitic cells present in our blood for their vital functions and it also results in decreases the motor nerve fiber, and skeletal muscle fibers which is responsible for muscle contractions, and movement at the spinal cord. It is also used to treat night leg cramps (muscle contraction). It produces its action by killing the parasite that causes infection and also helps to prevent the infections.

It is used in the treatment of the following conditions as parasitic infections such as Malaria, and Nocturnal leg cramps (night leg cramps).

Parasitic infections

It is an organism that lives in another organism like your body for its food and place to survive. You can get a parasitic infection from contaminated water, food, bug bites o sexual contact. It is a one-celled organism called protozoa which can be seen in the naked eye. Symptoms include stomach pain, nausea, vomiting, dehydration, weight loss, inflamed lymph nodes, constipation, diarrhea, rashes, eczema, hives, muscle, and joint pain.

Malaria

Rez-Q 600mg Injection (Quinine Sulphate) is used to treat the uncomplicated malaria disease (caused by a parasite), which leads to developing a fever, chills, nausea, vomiting, headache, muscle pain, etc.

Nocturnal leg cramps

Rez-Q 600mg Injection (Quinine Sulphate) is used to treat nocturnal leg cramps (night leg cramps, causes sleep disturbances) in adults and the elderly population.

 The Rez-Q 600mg Injection is prescribed in the following indications as Malaria, and Nocturnal leg cramps (night leg cramps).

Rez-Q 600mg Injection contains Quinine Sulphate 600mg is an antimalarial drug that produces its action by increasing the time (a toxic substance to parasites) in your blood. This kills the parasite that is present in your blood and inhibits the growth of bacteria that cause infections.

Rez-Q 600mg Injection contains Quinine Sulphate 600mg is an antimalarial drug that produces its action by increasing the haeme (a toxic substance to parasites) in your blood. This kills the parasite that is present in your blood and inhibits the growth of bacteria that cause infections.

• Do not take this medicine if you are allergic to Quinine sulfate
• It is contraindicated to use this medicine in patients who are having a history of G6PD deficiency, thrombocytopenia, hemolytic uremic syndrome, blackwater fever, myasthenia gravis, and optic neuritis
• Kindly avoid using this medicine if you have prolonged QT interval

• Flushing of the skin
• Hypoglycemia
• Epigastric pain
• Hepatitis
• Night blindness
• Diplopia
• Impaired hearing
• Fever
• Rash
• Optic atrophy

• How can you prevent yourself from getting malaria?

Avoid mosquito bites by covering your arms and legs by using a mosquito net, and insect repellent. Do not drink contaminated food and water always boil the water before you drink.

• How long does it take for malaria symptoms to show?

Usually, the symptoms start within 7 days after you get bitten by the infected mosquito. The incubation period may get differ from 7-18 days. The symptoms include feeling hot, shivery, muscle pain, vomiting, headache, and diarrhea.

• Can I stop taking the Rez-Q 600mg Injection when I feel better?

No, without completing the full course of treatment you should not withdraw the medicine even if you feel better because it may worsen your condition and result in the reoccurrence of infections.

Alcohol

It is not clear that consuming alcohol will affect the effect of the medicines. Kindly consult with your doctor.

Driving or operating machinery

It is considered unsafe to drive while you are receiving this medicine it may affect your ability to drive. Kindly consult with your doctor.

Pregnancy

The use of this medicine is considered unsafe during pregnancy because it may produce any harmful effects on the fetus. Kindly consult with your doctor

Breast Feeding

The use of this medicine is considered safe during breastfeeding because it does not excrete via breast milk. Kindly consult with your doctor

Kidney Problem

Rez-Q 600mg Injection should be used with caution in patients with renal impairment. The use of this medicine required dose modification. Kindly consult with your doctor.

Liver Disease

Rez-Q 600mg Injection should be used with caution in patients with hepatic impairment. The use of this medicine required dose modification. Kindly consult with your doctor.

Rez-Q 600mg Injection comes in an injection form and shakes well before use. It is injected by a health care professional in doctor clinics, hospitals. Use the injection as prescribed by your doctor. Do not discontinue the medicine when you feel better kindly consult together with your doctor.

It is considered to be safe to use this medicine in an adult patient if the drug is prescribed by a doctor. Kindly consult with your doctor.

It is considered unsafe to use this medicine in children who are below 16 years old. Kindly consult with your doctor.

Rez-Q 600mg Injection should be used with caution in patients with an elderly age group, which leads to developing further medical problems, leads to worsening the patient's health conditions. Kindly consult with your doctor. Dose modification or replacement is required based on the medical conditions of the patient.

• The use of this medicine may cause chronic renal impairment associated with the development of thrombotic thrombocytopenic purpura
• The use of this medicine may cause hypoglycemia in pregnant women because it stimulates the release of insulin from the pancreas
• Kindly avoid this medicine if you have any heart related diseases

• You have a history of gastrointestinal disease
• You are not responding to the treatment
• You have experienced any allergic reaction like rashes and itching
• You are having a concomitant disease or taking any medications

Rez-Q 600mg Injection consist of Quinine Sulphate 600mg used to treat Malaria, and Nocturnal leg cramps (night leg cramps).

Quinine Sulphate 600mg is an antimalarial drug, and an alkaloid obtained from cinchona bark, helpful in eradicating the malarial infection, and also used for reducing muscle contraction (night leg cramps) after administration of this drug.

Drug-Drug Interaction

Atracurium

The use of this drug is contraindicated because the use of quinine increases the effect of atracurium by pharmacodynamic synergism and it also increases the risk of developing respiratory depression

Mefloquine

The use of this drug is contraindicated because the combination of this drug increases the risk of developing ECG abnormalities and cardiac arrest.

Colchicine

Use alternative drugs because the use of quinine will increase the effect of colchicines by P-glycoprotein efflux transporter.

Mifepristone

Use alternative drugs because the use of mifepristone will increase the effect of quinine by affecting its hepatic and intestinal enzyme metabolism.

Amantadine

Therapy should be administered with caution because the use of quinine will increase the effect of amantadine by decreasing its renal clearance.

Digoxin

Therapy should be administered with caution because the use of digoxin will increase the effect of quinine by basic drug competition for renal tubular clearance.

Drug-Food Interaction

Consuming grapefruit along with quinine may interfere in the metabolism of this medicine.

Drug-Disease Interaction

QT PROLONGATION

Therapy should be administered with caution because the use of antimalarial may cause prolongation of QT interval, uncorrected hypokalemia, hypomagnesemia, bradycardia, and certain cardiac conditions.

Tinnitus

It is contraindicated to use this medicine in patients who are having tinnitus. The use of quinine is associated with reversible and irreversible ototoxicity. The use of this medicine may cause cystic degeneration of stria vascularis, degeneration of the cochlear neurons, and loss of hair cells.

Liver impairment

Therapy should be administered with caution in patients who are having hepatic impairment because the use of quinine decreases the oral clearance, and it also increases the volume of distribution and the half-life of the drug is prolonged.

Renal impairment

The use of this medicine may decrease the clearance level in patients with severe chronic renal failure.

Take the medicine as directed by the doctor don’t overdose on the medicine. If you have taken an overdose of this medicine immediately meet the doctor and rush to the nearby hospital.

Take the medicine as directed by the doctor. Do not skip the medicine, if you forgot to take the medicine or missed the dose. It is almost time for your next dose, skip the missed dose and go back to your regular schedule. Don’t take the extra dose take the regular dose immediately. Don’t use the two-dose at one time (Double Dose).

• Stored at 10-30°C room temperature.
• Protect from light and heat.
• Keep away from children and pets. Otherwise, it becomes toxic to them.
• Disposed of properly in a suitable bag.

Rez-Q 600mg Injection contains Quinine Sulfate 600mg used to treat parasitic infections such as Malaria. Quinine Sulphate 600mg is an antimalarial drug, and an alkaloid obtained from cinchona bark results in interacting with certain substances (required for vital functions of the malarial parasite cell) present in the blood. Also, results depress the motor nerve fiber and skeletal muscle fibers (responsible for muscle contractions, and movement) at the spinal cord. Then it eradicates the malarial infection and is also used for reducing the muscle contraction (night leg cramps) after administration of this drug.