Rezatrin Forte Tablet

Brand Name Rezatrin Forte Tablet
Salt Composition Artemether (80mg) + Lumefantrine (480mg)
Strength 80mg + 480mg
Product Form Tablet
Pack 6 Tablet(s) in Strip
Storage Store at room temperature (10-30°C)
Category Antimalarial
Country of Origin India
Manufacturer Shreya Life Sciences Pvt. Ltd
Manufacturer/Marketer AddressShreya Life Sciences Pvt. Ltd Shreya House, 301/a, Periera Hill Road, Andheri - East, Mumbai, 400101 India
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M.R.P : Rs.156.04       Price : Rs.124.83

You Save : Rs.31.21    Inclusive of all taxes

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6 Tablet(s) in Strip

Availability : In Stock

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    Medical Description of Rezatrin Forte Tablet

    Rezatrin Forte Tablet contains Artemether 80mg and Lumefantrine 480mg used to treat parasitic infections such as Malaria in both adults and children. Artemether 80mg and Lumefantrine 480mg is antimalarial drug, results in interacting with certain substances which are required for the malarial parasite present in the blood to do its vital functions. Then it eradicates the malarial infection caused by Plasmodium falciparum strains of malarial parasite. It is particularly used to treat malaria disease (resistant to other antimalarial medicines). Also, used to treat uncomplicated malaria disease with a combination of other antimalarial medicines. The combination of this medicine produces its action by killing the parasite that causes infection and also helps to prevent the infections.


    Rezatrin Forte Tablet Uses

    It is used in the treatment of the following conditions as parasitic infections such as Malaria


    Rezatrin Forte Tablet Benefits

    Parasitic infections

    It is an organism that lives in another organism like your body for its food and place to survive. You can get a parasitic infection from contaminated water, food, bug bites o sexual contact. It is a one-celled organism called protozoa which can be seen in the naked eye. Symptoms include stomach pain, nausea, vomiting, dehydration, weight loss, inflamed lymph nodes, constipation, diarrhea, rashes, eczema, hives, muscle, and joint pain.

    Malaria

    Rezatrin forte tablet is used to treat malaria disease caused by plasmodium falciparum strains of malarial parasite. Also, used to treat the malaria disease (resistant to other antimalarial medicines) which leads to developing a fever, chills, nausea, vomiting, headache, muscle pain, etc.


    Rezatrin Forte Tablet Indication

    The Rezatrin Forte Tablet is prescribed in the following indications as Malaria


    Mechanism of action of Rezatrin Forte Tablet

    The Rezatrin Forte Tablet contains Artemether 80mg and Lumefantrine 480mg it is a combination of two medicines. Artemether 80mg and Lumefantrine 480mg is antiparasitic medicine that produces their action by increasing the haeme (a toxic substance to parasites) in your blood. This kills the parasite that is present in your blood and inhibits the growth of bacteria that cause infections.


    How Rezatrin Forte Tablet works

    The Rezatrin Forte Tablet contains Artemether 80mg and Lumefantrine 480mg it is a combination of two medicines. Artemether 80mg and Lumefantrine 480mg is antiparasitic medicine that produces their action by increasing the haeme (a toxic substance to parasites) in your blood. This kills the parasite that is present in your blood and inhibits the growth of bacteria that cause infections.


    Rezatrin Forte Tablet Contraindication

    • Do not take this medicine if you are allergic to Artesunate, Mefloquine, Quinine, and Quinidine
    • It is contraindicated to use this medicine if you have psychiatric disorders and seizures
    • Kindly avoid using this medicine if you have taken the antifungal medicine recently


    Rezatrin Forte Tablet Side Effects

    • Headache
    • Dizziness
    • Sleep disturbances
    • Abdominal pain
    • Arthralgia (joint pain)
    • Myalgia (muscle pain)
    • Pruritus
    • Skin rashes
    • Hives
    • Wheezing
    • Increased heartbeat
    • Weight loss


    FAQs for Rezatrin Forte Tablet

    • How can you prevent yourself from getting malaria?

    Avoid mosquito bites by covering your arms and legs by using a mosquito net, and insect repellent. Do not drink contaminated food and water always boil the water before you drink.

    • How long does it take for malaria symptoms to show?

    Usually, the symptoms start within 7 days after you get bitten by the infected mosquito. The incubation period may get differ from 7-18 days. The symptoms include feeling hot, shivery, muscle pain, vomiting, headache, and diarrhea.

    • Can I stop taking the Rezatrin Forte Tablet when I feel better?

    No, without completing the full course of treatment you should not withdraw the medicine even if you feel better because it may worsen your condition and result in the reoccurrence of infections.


    Precautions and general warning of Rezatrin Forte Tablet

    Alcohol

    It is not clear that consuming alcohol will affect the effect of the medicines. Kindly consult with your doctor.

    Driving or operating machinery

    It is considered unsafe to drive while you are receiving this medicine it may affect your ability to drive. Kindly consult with your doctor.

    Pregnancy

    The use of this medicine is considered unsafe during pregnancy because it may produce any harmful effects on the fetus. Kindly consult with your doctor

    Breast Feeding

    The use of this medicine is considered safe during breastfeeding because it does not excrete via breast milk. Kindly consult with your doctor

    Kidney Problem

    Rezatrin Forte Tablet should be used with caution in patients with renal impairment. The use of this medicine required dose modification. Kindly consult with your doctor.

    Liver Disease

    Rezatrin Forte Tablet should be used with caution in patients with hepatic impairment. The use of this medicine required dose modification. Kindly consult with your doctor.


    How to Take Rezatrin Forte Tablet

    Rezatrin Forte Tablet is taken orally with or without food. You should not chew, cut or crush the tablet. Initially start with a low dose and slowly increase the dose once every week. Follow the direction mentioned within the label if you probably did not understand the appliance kindly ask your doctor or pharmacist to elucidate in detail. Do not withdraw the medicine when you feel better kindly complete the course of treatment to avoid reoccurrence.


    Use of Rezatrin Forte Tablet in Adult

    It is considered to be safe to use this medicine in an adult patient if the drug is prescribed by a doctor. Kindly consult with your doctor.


    Use of Rezatrin Forte Tablet in children

    It is considered unsafe to use this medicine in children who are below 2 years old. Kindly consult with your doctor.


    Use of Rezatrin Forte Tablet in Elderly Patients

    Rezatrin Forte Tablet should be used with caution in patients with an elderly age group, which leads to developing further medical problems, leads to worsening the patient's health conditions. Kindly consult with your doctor. Dose modification or replacement is required based on the medical conditions of the patient.


    Other general warnings

    • The use of this medicine may cause hypotension, dyspnea, urticaria, or generalized rash
    • Post-artesunate delayed hemolysis is characterized by a decrease in the level of hemoglobin and leads to cause hemolytic anemia
    • It is not approved for severe and uncomplicated P.falciparum infections
    • Kindly avoid using this medicine in patients who are having a history of congenital QT prolongation, electrolyte imbalance like hypokalemia, and hypomagnesemia

                  Drug resistance

    • You may develop resistance to the drug if you withdraw the drug without completing the full course of treatment.

                 Hormonal contraceptives

    • Rezatrin Forte Tablet (Artemether 80mg and Lumefantrine 480mg) alters the action of hormonal contraceptives. Based on the patient's health conditions, dose adjustment, or replacement is needed.

                 Severe complicated malarial infection

    • Rezatrin Forte Tablet (Artemether 80mg and Lumefantrine 480mg) is used to treat malaria disease, only when it is acute uncomplicated malaria, but not for severe, and complicated malaria.


    Talk to your doctor if

    • You have a history of gastrointestinal disease
    • You are not responding to the treatment
    • You have experienced any allergic reaction like rashes and itching
    • You are having a concomitant disease or taking any medications


    General instructions

    Rezatrin Forte Tablet consisting of Artemether 80mg and Lumefantrine 480mg are used to treat Acute uncomplicated malaria (caused by Plasmodium falciparum strains of malarial parasite).

    Artemether 80mg and Lumefantrine 480mg are the antimalarial drug combination together to prevent the malarial infection (caused by Plasmodium falciparum strains of malarial parasite) effectively. This drug combination is used to treat malaria disease, only when it is acute uncomplicated malaria, but not for severe, and complicated malaria.


    Drug Interaction of Rezatrin Forte Tablet

    Drug-Drug Interaction

    Tepotinib

    Use alternative drugs because the use of sotorasib will decrease the effect of artemether and lumefantrine by P-glycoprotein efflux transporter.

    Carbamazepine
    Therapy should be administered with caution because the use of carbamazepine will decrease the effect of artemether and lumefantrine by increasing its metabolism.

    Diclofenac

    Therapy should be administered with caution because the use of diclofenac will increase the effect of artemether and lumefantrine by decreasing its metabolism.

    Chloroquine

    It is contraindicated to use this medicine because the combination of artemether and lumefantrine increases the toxicity of chloroquine by QTc interval.

    Drug-Food Interaction

    Food may increase the effect of this medicine on your body. So take the medicine as soon you complete your meal.

    Drug-Disease Interaction

    Liver diseases

    It should be used with caution in a patient with hepatic impairment or liver disease. Then it leads to the risk of liver damage. Based on the patient clinical conditions, dose adjustment or replacement is needed.

    Kidney diseases

    It should be used with caution in a patient with renal impairment or kidney disease. Then it leads to the risk of kidney damage. Based on the patient clinical conditions, dose adjustment or replacement is needed.

    Hematological toxicity

    Therapy should be used with caution in patients with hematological toxicity (leads to developing anemia, leukemia, thrombocytopenia, etc.), which leads to worsening the patient's health conditions. Based on the patient's health conditions, dose adjustment, or replacement is needed.

    QT Prolongation

    Rezatrin Forte Tablet (Artemether 80mg and Lumefantrine 480mg) should be used with caution in patients with QT Prolongation (heart diseases, irregular heartbeat, etc.), which leads to worsening the patient health conditions. Based on the patient's health conditions, dose adjustment, or replacement is needed.


    Over Dose

    Take the medicine as directed by the doctor don’t overdose on the medicine. If you have taken an overdose of this medicine immediately meet the doctor and rush to the nearby hospital.


    Missed Dose

    Take the medicine as directed by the doctor. Do not skip the medicine, if you forgot to take the medicine or missed the dose. It is almost time for your next dose, skip the missed dose and go back to your regular schedule. Don’t take the extra dose take the regular dose immediately. Don’t use the two-dose at one time (Double Dose).


    Storage and Disposal

    • Stored at 10-30°C room temperature.
    • Protect from light and heat.
    • Keep away from children and pets. Otherwise, it becomes toxic to them.
    • Disposed of properly in a suitable bag.


    Fast Tag

    Rezatrin Forte Tablet contains Artemether 80mg and Lumefantrine 480mg used to treat parasitic infections such as Malaria in both adults and children. Artemether 80mg and Lumefantrine 480mg are the antimalarial drug combination together to prevent the malarial infection(caused by Plasmodium falciparum strains of malarial parasite) effectively. This drug combination is used to treat malaria disease, only when it is acute uncomplicated malaria, but not for severe, and complicated malaria.