Ronyglim M 2mg/500mg Tablet

Ronyglim M 2mg/500mg Tablet is an anti-diabetic drug used to treat type 2 diabetes mellitus to the patient who cannot control diabetes by diet and exercise. Consume the tablet before the meals. It is the combination of Glimepiride and Metformin. The combination of this drug lowers the blood sugar level by increasing the amount of insulin that is released by the pancreas and it also lowers the production of glucose in the liver and delays the glucose absorption from the intestines.

It is used to treat Type 2 diabetes mellitus

Used in the treatment of the following disease such as

Type 2 diabetes mellitus

It is also called adult-onset diabetes. It is a chronic condition in which our body does not produce enough insulin or resist insulin and it may increase the risk of cardiovascular diseases like chest pain and heart attack.

The combination of this drug lowers the blood sugar level by increasing the amount of insulin that is released by the pancreas and it also lowers the production of glucose in the liver and delays the glucose absorption from the intestines. It is used to treat Type 2 diabetes mellitus

• It is the combination of Glimepiride and Metformin
• Glimepiride increases the effect of beta-cell insulin secretion and it also decreases the production of hepatic glucose and increases the sensitivity of insulin receptors.
• Metformin is a biguanide that produces its action by decreasing the production of hepatic and GI glucose absorption, it also increases the insulin sensitivity

The combination of this drug lowers the blood sugar level by increasing the amount of insulin that is released by the pancreas and it also lowers the production of glucose in the liver and delays the glucose absorption from the intestines.

• If you are allergic to the composition of the medicine
• If you are having ketoacidosis and type 1 diabetes mellitus

• Angioedema
• Urticaria
• Rash
• Pruritus
• Photosensitivity reaction
• Heartburn
• Vasculitis
• Pancytopenia
• Myalgia
• Blurred vision
• Nausea/vomiting
• Hypoglycemia

• What is the Ronyglim M 2mg/500mg Tablet?

Ronyglim M 2mg/500mg Tablet is an anti-diabetic drug used to treat type 2 diabetes mellitus. Consume the tablet before the meals. It is the combination of Glimepiride and Metformin. The combination of this drug lowers the blood sugar level by increasing the amount of insulin that is released by the pancreas and it also lowers the production of glucose in the liver and delays the glucose absorption from the intestines.

• Does Ronyglim M 2mg/500mg Tablet cause hypoglycemia?

Yes, the use of Ronyglim M 2mg/500mg Tablet leads to hypoglycemia this usually occurs when you skip your meal after taking the medication.

• What is the instruction for storage and disposal of Ronyglim M 2mg/500mg Tablet?

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct sunlight. Keep out of the reach of children. Do not keep outdated medicine. Ask your doctor or pharmacist how to dispose of medicine that is not in use and store below 30C

• How long do I need to take the Ronyglim M 2mg/500mg Tablet? Can I stop the medication?

Usually, the anti-diabetic drug is prescribed for long-term use. This medicine controls the blood sugar level but does not completely cure diabetes. Take the medicine as per your doctor's advice.

• What can happen if I take more than the recommended dose of Ronyglim M 2mg/500mg Tablet?

Consuming more amount of tablets than the prescribed dose may lead to overdose. Kindly use the medicine as per your doctor advice

Alcohol

Alcohol may affect the patient blood sugar level either by increasing or by decreasing it depends upon the amount you have consumed. Avoid drinking alcohol when you are having diabetes

Driving or operating machinery

It is not considered safe to drive because the use of this drug may increase or decrease the sugar level. Use with caution kindly consults with your doctor

Pregnancy

It is considered unsafe during pregnancy it may produce harmful effects on the fetus. Kindly consult with your doctor

Breast Feeding

It is considered safe during breastfeeding it does not excrete via breast milk. Kindly consult with your doctor

Kidney Problem

It is considered unsafe to use this medicine for a patient who is having a renal impairment. Kindly consult with your doctor

Liver Disease

Use caution to the patient who is having liver disease. Kindly consult with your doctor

The tablet should be taken orally by mouth two times daily before meals. Follow the direction mentioned in the label if you did not understand the application kindly ask your doctor or pharmacist to explain the details. Do not discontinue the medicine when you feel better kindly consult with your doctor.

No data available kindly consult with your doctor

It should be used with extra caution to the elderly patient there is a high risk of getting chances of low blood sugar

• If you are allergic to the composition of the medicine
• If you are using any concomitant medication
• If you are not responding to the treatment
• If you are having liver and kidney disease

• This tablet should be taken orally
• Monitor the patient liver and hepatic enzymes for 6 to 12 months
• Do not use this medicine to the patient who is having lactic acidosis

Drug-Drug Interaction

Ethanol + Glimepiride

More consumption of ethanol may alter glycemic control and may produce a disulfram like reaction. It is contraindicated to use.

Aripiprazole + Glimepiride

A combination of Aripiprazole and Glimepiride may alter the blood glucose level. Kindly monitor the patient’s glucose level

Aminolevulinic acid Oral + Glimepiride

The combination of this drug either increases the effect of others by pharmacodynamic synergism. Use alternative drug

Aspirin + Glimepiride

Aspirin increases the effect of Glimepiride by an unknown mechanism. Use the medicine with caution

Ciprofloxacin + Glimepiride

Ciprofloxacin increases the effect of Glimepiride by pharmacodynamic synergism. Kindly monitor the patient’s glucose levels

Ethanol + Metformin

Ethanol increases the toxicity of metformin by others. More consumption of ethanol may alter glycemic control and may produce a disulfiram-like reaction. It is contraindicated to use.

Ranolazine + Metformin

Ranolazine increases the effect of metformin by decreasing its elimination. Use alternative drug

Tranylcypromine + Metformin

Tranylcypromine will increase the effect of metformin by an unspecified interaction mechanism. Use alternative drug

Acetazolamide + Metformin

Acetazolamide increases the toxicity of metformin by others. Closely monitor the patient serum bicarbonate level

Amiodarone + Metformin

Amiodarone increases the effect of metformin by cationic drug competition for renal tubular clearance. Use with caution

Betamethasone + Metformin

Betamethasone decreases the effect of metformin by pharmacodynamic antagonism. Use with caution

Drug-Food Interaction

Alcohol may affect the patient blood sugar level either by increasing or by decreasing it depends upon the amount you have consumed and it also causes lactic acidosis. Avoid drinking alcohol when you are having diabetes

Drug-Disease Interaction

Cardiovascular risk

The use of anti-diabetic drugs may increase the risk of cardiovascular mortality rate when compared with diet or diet with insulin. Kindly monitor the patient cardiac function

Renal and hepatic dysfunction:

The tablet gets precipitated to the patient who is having a renal impairment and it should be given cautiously to the patient who is having renal impairment

Diabetic ketoacidosis

The use of this tablet to the patient who is having diabetic ketoacidosis is contraindicated.

Glucose 6-phosphate dehydrogenase deficiency

Sulfonylureas can cause hemolyticanemia in the patient who is having glucose 6-phosphate dehydrogenase deficiency. Use with caution.

Hyponatremia

Sulfonylureas can cause hyponatremia or increase the release of antidiuretic hormone. Use with caution to the elderly patient who is using diuretics.

Lactic acidosis

Use of Metformin to the patient who is having renal dysfunction, liver disease, congestive heart failure, dehydration, shock, myocardial infarction may lead to developing lactic acidosis. Kindly use with caution.

Hypoglycemia

During anti-diabetic medication, patients can experience hypoglycemia. Use with caution to the patient who is having adrenal insufficiency, autonomic neuropathy and receiving beta-adrenergic blocking agent

Vitamin B12 deficiency

Prolonged use of metformin can interfere in the absorption of vitamin b12 in the stomach. It may lead to anemia, tingling sensation, numbness in hands and feet, and ataxia. To avoid this effect kindly take the vitamin b12 from outside sources once a year

Consuming more amount of tablets than the prescribed dose may lead to overdose. Kindly use the medicine as per your doctor advice

If you missed the dose take it as soon as you remember do not take the tablet between the meals. If it is time for the next dose skip the missed dose and continue with a regular dose

• Store the medicine in a closed container at room temperature, away from heat, moisture, and direct sunlight
• Keep out of the reach of children
• Do not keep outdated medicine
• Ask your doctor or pharmacist how to dispose of medicine that is not in use
• Store below 30C

• Glimepiride and metformin is Sulfonylureas and biguanide derivatives
• It is an anti-diabetic drug
• It is used to treat type 2 diabetes mellitus
• The tablet should be taken orally by mouth two times daily before meals
• Do not use this medicine if you are allergic to the composition of the medicine