Rycillin-TZ Injection

Brand Name Rycillin-TZ Injection
Salt Composition

Piperacillin (4000mg) + Tazobactum (500mg)

Strength 4000mg + 500mg
Product Form Injection
Pack 1 Injection in 1 Vial
Storage Store below 30°C
Category

Antibiotic

SubCategory

Anti-Biotic

Country of Origin India
Manufacturer

Ryland Healthcare

Manufacturer/Marketer Address Ryland Healthcare Plot No. 295, Basement, Industrial Area Phase 2, Panchkula, Haryana 134113
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M.R.P : Rs.434.61       Price : Rs.391.15

You Save : Rs.43.46    Inclusive of all taxes

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1 Injection in 1 Vial

Availability : In Stock

  Online Payment Only

  Non Returnable Read More



    Medical Description of Rycillin-TZ Injection

    Rycillin-TZ injection contains Piperacillin 4000mg and Tazobactam 500mg used to treat following bacterial conditions such as Pneumonia, Urinary tract infections, Intraabdominal infections, Skin and skin structure infections, Neutropenia with fever, and Gynecological infections. Piperacillin 4000mg is an antibiotic used to treat severe bacterial infections. It is also used before surgery to prevent bacterial infections. Mainly this bacterial infection targets the lungs and urinary tract. Tazobactam 500mg is a β lactamase inhibitor. It should be given with antibiotic, which works by inhibiting the β lactamase enzyme (destroys the action of antibiotics) produced by bacteria.  The combination of this medicine helps to fight against microbes and also prevents the growth of bacteria. It is also used to prevent the infections that occur during surgery. This medicine is not used for common flu and cold symptoms that occur due to viral infections. This medicine is commonly prescribed for cough and colds caused by bacterial infections.


    Rycillin-TZ Injection Uses

    It is used in the treatment of the following conditions as Pneumonia, Urinary tract infections, Intraabdominal infections, Skin and skin structure infections, Neutropenia with fever, and Gynecological infections.


    Rycillin-TZ Injection Benefits

    Bacterial infections

    Bacterial infection occurs when bacteria enter your body and start multiplying which may cause tissue damage and make you sick. Mostly it is caused by Staphylococcus and Streptococcus organisms. The bacterial diseases are cholera, bacterial meningitis, tetanus, gonorrhea, pneumonia, and syphilis. Symptoms include fever, chills, and sweats, inflamed lymph nodes, headache, diarrhea, abdominal pain

    Urinary tract infection

    It is a type of infection that affects the urethra, kidneys, and bladder. It is caused by Escherichia coli (E.coli). Symptoms include abdominal pain, frequent urination, dysuria, blood in urine, foul-smell while urinating

    Pneumonia

    Infection and inflammation to the respiratory air sacs of lungs. It is caused by Streptococcus pneumonia. Symptoms include chest pain, cough, fatigue, fever, shortness of breath, confusion and diarrhea.

    Intraabdominal infections

    It is an accumulation of fluid surrounded by inflamed tissue which is present inside your bellies such as peritonitis, pancreatitis, diverticulitis, cholecystitis, and cholangitis. It is caused by Enterobacteriaceae, Enterococci, and Bacteroides fragilis. Symptoms include lack of appetite, belly pain, fever, change in bowel movements, and rectal tenderness.

    Skin and skin structure infections

    Infections such as cellulitis wound infection and cutaneous abscess caused by bacteria are related to skin and skin structure infections, treated by this medicine.

    Neutropenia with fever

    It is a occurrence of fever during a period of neutropenia. Chemotherapy is the major cause for neutropenia. Symptoms include fever, sores, swelling and repeated infections.

    Gynecological infections

    Infection to the vagina or genital tract caused by E.coli etc called gynecological infections includes endometriosis, pelvic inflammatory diseases, etc.


    Rycillin-TZ Injection Indication

    Rycillin-TZ injection is prescribed in the following indications as Pneumonia, Urinary tract infections, Intraabdominal infections, Skin and skin structure infections, Neutropenia with fever, and Gynecological infections.


    Mechanism of action of Rycillin-TZ Injection

    Rycillin-TZ injection contains Piperacillin 4000mg and Tazobactum 500mg is a combination of two medicines. Piperacillin 4000mg is an Ureidopenicillins (Penicillin) antibiotic that produces its action by preventing the bacterial cell wall synthesis which is essential for the growth of bacteria and it also prevents the spreading of infections. Tazobactam 500mg is a beta-lactamase inhibitor that produces its action by inhibiting the enzymes which are produced by the bacteria. This enzyme inactivates the effect of the antibiotic. The combination with Tazobactum helps to reduce the development of resistance and increase the action of Piperacillin against bacteria.


    How Rycillin-TZ Injection works

    Rycillin-TZ injection contains Piperacillin 4000mg and Tazobactum 500mg is a combination of two medicines. Piperacillin 4000mg is an Ureidopenicillins (Penicillin) antibiotic that produces its action by preventing the bacterial cell wall synthesis which is essential for the growth of bacteria and it also prevents the spreading of infections. Tazobactam 500mg is a beta-lactamase inhibitor that produces its action by inhibiting the enzymes which are produced by the bacteria. This enzyme inactivates the effect of the antibiotic. The combination with Tazobactum helps to reduce the development of resistance and increase the action of Piperacillin against bacteria.


    Rycillin-TZ Injection Contraindication

    • Do not take this medicine if you are allergic to Piperacillin and Tazobactam
    • It is contraindicated to use this medicine if you have a history of allergic reaction to penicillin, Imipenem, and other cephalosporins
    • Kindly avoid this medicine if you are having hepatic and renal impairment, Seizures


    Rycillin-TZ Injection Side Effects

    • Seizure
    • Rash
    • Hemolytic anemia
    • Positive Coombs reaction
    • Prolonged prothrombin time
    • Interstitial nephritis
    • Hypersensitivity
    • Anaphylaxis
    • Thrombophlebitis
    • Injection site pain
    • Headache
    • Fever
    • Intestinal infection due to pseudomonas


    FAQs for Rycillin-TZ Injection

    • How long should I take the Rycillin-TZ injection?

    Normally the duration of this medicine depends upon the severity of the disease. You should take this according to your doctor advice

    • Is the Rycillin-TZ injection is effective?

    Yes, it is considered effective when you have taken the medication as per the dose and duration advised by the doctor. If you stop the medicine without completing the course of treatment it may worsen the conditions

    • What if I do not get better after using the Rycillin-TZ injection?

    If you do not feel better after completing the full course of treatment kindly inform your doctor.


    Precautions and general warning of Rycillin-TZ Injection

    Alcohol

    The use of alcohol does not produce harmful effects while you are receiving this treatment. Kindly consult with your doctor

    Driving or operating machinery

    It is considered unsafe to drive while you are receiving this medicine it may affect your ability to drive. Kindly consult with your doctor.

    Pregnancy

    The use of this medicine is considered safe during pregnancy because it does not produce a harmful effect on the developing fetus. Kindly consult with your doctor

    Breast Feeding

    The use of this medicine is considered safe during breastfeeding because it does not excrete via breast milk. Kindly consult with your doctor

    Kidney Problem

    The medicine should be used with caution in patients with renal impairment. The use of this medicine required dose modification. Kindly consult with your doctor.

    Liver Disease

    It is considered safe to use this medicine in patients who are having hepatic impairment. The use of this medicine does not require dose modification. Kindly consult with your doctor.


    How to Take Rycillin-TZ Injection

    Rycillin-TZ injection comes in a liquid solution as an intravenous injection. It is injected by a health care professional in doctor clinics, hospitals. Use the injection as prescribed by your doctor. Do not discontinue the medicine when you feel better kindly consult together with your doctor.


    Use of Rycillin-TZ Injection in Adult

    It is considered to be safe to use this medicine in an adult patient if the drug is prescribed by a doctor. Kindly consult with your doctor.


    Use of Rycillin-TZ Injection in children

    It is considered safe to use this medicine in children. Kindly consult with your doctor.


    Use of Rycillin-TZ Injection in Elderly Patients

    Rycillin-TZ injection should be used with caution in patients with an elderly age group, which leads to developing further medical problems, leads to worsening the patient's health conditions. Kindly consult with your doctor. Dose modification or replacement is required based on the medical conditions of the patient.


    Other general warnings

    • Therapy should be administered with caution in patients who allergic to penicillin
    • Therapy should be administered with caution in patients who are having a history of seizure
    • The use of this medicine may cause antibiotic-associated diarrhea
    • In renal impairment patients, there is a risk of developing a bleeding complication
    • During prolonged treatment, kindly monitor renal and hepatic, and hematopoietic functions
    • Combination with piperacillin/tazobactam and vancomycin may be associated with an increase in acute renal injury


    Talk to your doctor if

    • You have a history of gastrointestinal disease
    • You are not responding to the treatment
    • You are having any concomitant diseases


    General instructions

    Rycillin-TZ injection contains Piperacillin 4000mg and Tazobactam 500mg used to treat following bacterial conditions such as Pneumonia, Urinary tract infections, Intraabdominal infections, Skin and skin structure infections, Neutropenia with fever, and Gynecological infections. Piperacillin 4000mg is an antibiotic used to treat severe bacterial infections. It is also used before surgery to prevent bacterial infections. Mainly this bacterial infection targets the lungs and urinary tract. Tazobactam 500mg is a β lactamase inhibitor. It should be given with antibiotic, which works by inhibiting the β lactamase enzyme (destroys the action of antibiotics) produced by bacteria.  The combination of this medicine helps to fight against microbes and also prevents the growth of bacteria.


    Drug Interaction of Rycillin-TZ Injection

    Drug-Drug Interaction

    BCG vaccine live

    The use of this drug is contraindicated because the use of medicine decreases the effect of the BCG vaccine live by pharmacodynamic antagonism

    Cholera vaccine

    Use alternative drugs, because the use of the cholera vaccine with antibiotics may activate the vaccine strain. So, avoid receiving this combination of medicines before 14 days of vaccination

    Estradiol

    Therapy should be administered with caution because the use of piperacillin will decrease the effect of estradiol by altering the intestinal flora and it also lowers the risk of contraceptive failure

    Warfarin

    Therapy should be administered with caution because the combination of this drug may decrease the vitamin K producing intestinal flora and increase the INR level after a few days

    Furosemide

    The use of piperacillin increase the toxicity of furosemide by pharmacodynamic synergism and it also increases the risk of developing nephrotoxicity

    Aspirin

    The use of piperacillin will increase the effect of aspirin by acidic drug competition for renal tubular clearance.

    Chloramphenicol

    It is an antibiotic used to treat bacterial infections like conjunctivitis. This medicine alters the action of chloramphenicol

    Drug-Food Interaction

    The food may increase the effect of the drug in your body so it is advised to take this medicine with food to increase the absorption

    Drug-Disease Interaction

    Colitis

    This medicine kills the good helpful bacteria in your stomach or intestine and causes diarrhea. This drug should be used caution in patients with gastrointestinal disease, especially colitis (swelling of the colon inner lining). It leads to worsening the patient’s health condition.

    Kidney disease

    This medicine is filtered by the kidneys and passes through the urine. Then it leads to the risk of kidney damage. It should be used with caution in a patient with kidney disease. Inform your doctor and then take. Based on the patient's condition, dose adjustment is needed.

    Seizures

    Using this medicine is needs caution in patients with seizures or fits. Inform the doctor, then will do dose adjustment if necessary to take this medicine with seizure medications.

    Liver disease

    Therapy should be administered with caution because the use of Cephalosporins may increase the SGOT, SGPT, and Alkaline phosphatase levels.


    Over Dose

    Take the medicine as directed by the doctor don’t overdose on the medicine. If you have taken an overdose of this medicine immediately meet the doctor and rush to the nearby hospital.


    Missed Dose

    Take the medicine as directed by the doctor. Do not skip the medicine, if you forgot to take the medicine or missed the dose. It is almost time for your next dose, skip the missed dose and go back to your regular schedule. Don’t take the extra dose take the regular dose immediately. Don’t use the two-dose at one time (Double Dose).


    Storage and Disposal

    • Stored at 10-30°C room temperature.
    • Protect from light and heat.
    • Keep away from children and pets. Otherwise, it becomes toxic to them.
    • Disposed of properly in a suitable bag.


    Fast Tag

    Rycillin-TZ injection contains Piperacillin 4000mg and Tazobactam 500mg used to treat following bacterial conditions such as Pneumonia, Urinary tract infections, Intraabdominal infections, Skin and skin structure infections, Neutropenia with fever, and Gynecological infections.  Piperacillin 4000mg is an Ureidopenicillins (Penicillin) antibiotic used to treat severe bacterial infections. It blocks the bacterial cell wall synthesis which is essential for bacterial growth. Tazobactam 500mg is a β lactamase inhibitor to inhibit the β lactamase enzyme produced by bacteria. This enzyme destroys the action of antibiotics. This drug combination together prevents the infection effectively.

    This medicine is not used for common flu and cold symptoms. And not treat viral infections. This medicine is commonly prescribed for cough and colds caused by bacterial and parasitic infections.

    This medicine is contraindicated to allergic symptoms such as skin rash, itching, swelling, and breathing difficulties.