Sefepime 1gm Injection

Sefepime 1gm Injection contains Cefepime 1gm used to treat following bacterial infections such as Urinary tract infections, Pneumonia, Febrile pneumonia, Bacterial meningitis, Bacterial septicemia, Skin and soft tissue infections, Osteomyelitis (Bone and joint infection), Intraabdominal infection, Bacteremia, Bacterial endocarditis and Pyelonephritis. Cefepime 1gm is an antibiotic used to treat severe bacterial infections. Mainly this bacterial infection targets the lungs, nose, skin and soft tissues, bone and joints, kidney, heart, blood, abdomen and urinary tract. This medicine is not used for common flu and cold symptoms that occur due to viral infections. This medicine is commonly prescribed for cough and colds caused by bacterial infections.

It is used in the treatment of the following conditions as Urinary tract infections, Pneumonia, Febrile pneumonia, Bacterial meningitis, Bacterial septicemia, Skin and soft tissue infections, Osteomyelitis (Bone and joint infection), Intraabdominal infection, Bacteremia, Bacterial endocarditis and Pyelonephritis

Bacterial infections

Bacterial infection occurs when bacteria enter your body and start multiplying which may cause tissue damage and make you sick. Mostly it is caused by Staphylococcus and Streptococcus organisms. The bacterial diseases are cholera, bacterial meningitis, tetanus, gonorrhea, pneumonia and syphilis. Symptoms include fever, chills and sweats, inflamed lymph nodes, headache, diarrhea, abdominal pain

Urinary tract infection

It is a type of infection that affects the urethra, kidneys, and bladder. It is caused by Escherichia coli (E.coli). Symptoms include abdominal pain, frequent urination, dysuria, blood in urine, foul-smell while urinating

Acute bronchitis

It is a viral infection that causes inflammation in the bronchial tubes. It is mostly caused by rhinovirus, adenovirus, influenza A and B and parainfluenza virus. Symptoms include cough, fatigue, breathing difficulty, fever and chills and chest discomfort.

Bone and joint infection

Bone infection is also called Osteomyelitis. It is caused by bacteria called staphylococcus which travels through the bloodstream to the weak area in a bone. Symptoms include fever, pain, fatigue, tenderness, redness and warmth.

Lower respiratory tract infections

Infection in the lungs especially in the lower airways Common infections are Bronchiolitis and Pneumonia which are caused by Streptococcus pneumonia. Symptoms include runny nose, dry cough, sore throat, low-grade fever and headache.

Tonsillitis/Pharyngitis

Infection of the swelling and soreness in the throat and tonsils is called pharyngitis and tonsillitis. The infection that affects both throat and tonsil is called pharyngotonsillitis. It is caused by bacteria.

Endocarditis

Infection in the inner lining of the heart. It usually occurs when the bacteria enter your bloodstream by destroying your immune system. Symptoms include muscle pain, fatigue, fever, chills, night sweats, shortness of breath, heart murmur and swelling.

Pneumonia

Infection and inflammation to the respiratory air sacs of lungs. It is caused by Streptococcus pneumonia. Symptoms include chest pain, cough, fatigue, fever, shortness of breath, confusion and diarrhea.

Febrile Neutropenia

It is a occurrence of fever during a period of neutropenia. Chemotherapy is the major cause for neutropenia. Symptoms include fever, sores, swelling and repeated infections.

Bacterial meningitis

Infection and inflammation to the meninges (in the brain). It is caused by Streptococcus pneumonia, Neisseria meningtidis, Haemophilus influenza. Symptoms include high fever, stiff neck, severe headache, confusion and sensitivity to light.

Bacterial septicemia

Infection of the blood caused by bacteria leads to increased toxins in the bloodstream passes to the entire body develops organ damage. It occurs due to urinary tract infections, lung infections, kidney infections and infection in the abdominal area. Symptoms include irregular heartbeat, fever, chills, breathing fast, reduces urine volume, red dots and shock.

Skin and soft tissue infections

Infections such as cellulitis wound infection and cutaneous abscess caused by Streptococcus pyogenes and Staphylococcus aureus bacteria are related to skin and skin structure infections, treated by this medicine.

Pyelonephritis

Infection of the kidney. It is caused by gram-negative bacteria such as E.coli, Proteus, Klebsiella, and Enterobacter. Symptoms include pain, urinary tract infections, blood in urine, fever, loss of appetite, fast heart rate.

Sefepime 1gm Injection is prescribed in the following indications as Urinary tract infections, Pneumonia, Febrile pneumonia, Bacterial meningitis, Bacterial septicemia, Skin and soft tissue infections, Osteomyelitis (Bone and joint infection), Intraabdominal infection, Bacteremia, Bacterial endocarditis and Pyelonephritis

Sefepime 1gm Injection contains Cefepime 1gm is a fourth-generation cephalosporin antibiotic that produces its action by preventing the bacterial cell wall synthesis which is essential for the growth of bacteria and it also prevents the spreading of infections.

Sefepime 1gm Injection contains Cefepime 1gm is a fourth-generation cephalosporin antibiotic that produces its action by preventing the bacterial cell wall synthesis which is essential for the growth of bacteria and it also prevents the spreading of infections.

• Do not take this medicine if you are allergic to Cefepime
• It is contraindicated to use this medicine if you have a history of allergic reaction to penicillin and other cephalosporins
• Kindly avoid this medicine if you are having hepatic and renal impairment, Seizures

• Elevated alanine aminotransferase
• Hypophosphatemia
• Diarrhea
• Eosinophilia
• Normal partial thromboplastin time
• Agranulocytosis
• Encephalopathy
• Rash
• Erythema at the injection site
• Pain
• Pruritus
• Leukopenia
• Neuromuscular excitability

• How long should I take the Sefepime 1gm Injection?

Normally the duration of this medicine depends upon the severity of the disease. You should take this according to your doctor advice

• Is the Sefepime 1gm Injection is Effective?

Yes, it is considered effective when you have taken the medication as per the dose and duration advised by the doctor. If you stop the medicine without completing the course of treatment it may worsen the conditions

• What if I do not get better after using the Sefepime 1gm Injection?

If you do not feel better after completing the full course of treatment kindly inform your doctor.

Alcohol

The use of alcohol does not produce harmful effects while you are receiving this treatment. Kindly consult with your doctor.

Driving or operating machinery

It is considered unsafe to drive while you are receiving this medicine it may affect your ability to drive. Kindly consult with your doctor.

Pregnancy

The use of this medicine is considered safe during pregnancy because it does not produce a harmful effect on the developing fetus. Kindly consult with your doctor.

Breast Feeding

The use of this medicine is considered safe during breastfeeding because it does not excrete via breast milk. Kindly consult with your doctor.

Kidney Problem

The medicine should be used with caution in patients with renal impairment. The use of this medicine required dose modification. Kindly consult with your doctor.

Liver Disease

It is considered safe to use this medicine in patients who are having a hepatic impairment. The use of this medicine does not require dose modification. Kindly consult with your doctor.

Sefepime 1gm Injection comes in a liquid solution as an intramuscular, intravenous injection. It is injected by a health care professional in doctor clinics, hospitals. Use the injection as prescribed by your doctor. Do not discontinue the medicine when you feel better kindly consult together with your doctor.

It is considered to be safe to use this medicine in an adult patient if the drug is prescribed by a doctor. Kindly consult with your doctor.

It is considered safe to use this medicine in children. Kindly consult with your doctor.

Sefepime 1gm Injection should be used with caution in patients with an elderly age group, which leads to developing further medical problems, leads to worsening the patient's health conditions. Kindly consult with your doctor. Dose modification or replacement is required based on the medical conditions of the patient.

• Therapy should be administered with caution in patients who allergic to penicillin.
• Therapy should be administered with caution in patients who are having a history of seizure.
• The use of this medicine may cause antibiotic-associated diarrhea.
• Intramuscular injection is recommended only to the patients who are having mild-moderate complicated or uncomplicated urinary tract infection that occurs due to E.coli
• Long-term use may cause superinfection.
• The use of this medicine may increase the international normalized patients (INR)
• Therapy should be administered with caution if you have GI disease, like colitis.
• The use of this medicine may cause neurotoxicities such as aplaxia, encephalopathy, myoclonus, seizures and nonconvulsive status epilepticus.

• You have a history of gastrointestinal disease.
• You are not responding to the treatment.
• You are having any concomitant diseases.

The Sefepime 1gm Injection contains Cefepime 1gm used to treat following bacterial infections such as Urinary tract infections, Pneumonia, Febrile pneumonia, Bacterial meningitis, Bacterial septicemia, Skin and soft tissue infections, Osteomyelitis (Bone and joint infection), Intraabdominal infection, Bacteremia, Bacterial endocarditis and Pyelonephritis. Cefepime 1gm is an antibiotic used to treat severe bacterial infections. Mainly this bacterial infection targets the lungs, nose, skin and soft tissues, bone and joints, kidney, heart, blood, abdomen, and urinary tract.

Drug-Drug Interaction

BCG vaccine live

The use of this drug is contraindicated because the use of medicine decreases the effect of the BCG vaccine live by pharmacodynamic antagonism.

Cholera vaccine

Use alternative drugs, because the use of the cholera vaccine with antibiotics may activate the vaccine strain. So, avoid receiving this combination of medicines before 14 days of vaccination.

Estradiol

Therapy should be administered with caution because the use of cefepime will decrease the effect of estradiol by altering the intestinal flora and it also lowers the risk of contraceptive failure.

Warfarin

Therapy should be administered with caution because the combination of this drug may decrease the vitamin K producing intestinal flora and increase the INR level after a few days.

Furosemide

The use of cefepime increase the toxicity of furosemide by pharmacodynamic synergism and it also increases the risk of developing nephrotoxicity.

Aspirin

The use of cefepime will increase the effect of aspirin by acidic drug competition for renal tubular clearance.

Chloramphenicol

It is an antibiotic used to treat bacterial infections like conjunctivitis. This medicine alters the action of chloramphenicol.

Drug-Food Interaction

The food may increase the effect of the drug in your body so it is advised to take this medicine with food to increase the absorption.

Drug-Disease Interaction

Colitis

This medicine kills the good helpful bacteria in your stomach or intestine and causes diarrhea. This drug should be used caution in patients with gastrointestinal disease, especially colitis (swelling of the colon inner lining). It leads to worsening the patient’s health condition.

Kidney disease

This medicine is filtered by the kidneys and passes through the urine. Then it leads to the risk of kidney damage. It should be used with caution in a patient with kidney disease. Inform your doctor and then take. Based on the patient's condition, dose adjustment is needed.

Seizures

Using this medicine is needs caution in patients with seizures or fits. Inform the doctor, then will do dose adjustment if necessary to take this medicine with seizure medications.

Liver disease

Therapy should be administered with caution because the use of Cephalosporins may increase the SGOT, SGPT and Alkaline phosphatase levels.

Take the medicine as directed by the doctor don’t overdose on the medicine. If you have taken an overdose of this medicine immediately meet the doctor and rush to the nearby hospital.

Take the medicine as directed by the doctor. Do not skip the medicine, if you forgot to take the medicine or missed the dose. It is almost time for your next dose, skip the missed dose and go back to your regular schedule. Don’t take the extra dose take the regular dose immediately. Don’t use the two-dose at one time (Double Dose).

• Stored at 10-30°C room temperature.
• Protect from light and heat.
• Keep away from children and pets. Otherwise, it becomes toxic to them.
• Disposed of properly in a suitable bag.

• Sefepime 1gm Injection contains Cefepime 1gm used to treat following bacterial infections such as Urinary tract infections, Pneumonia, Febrile pneumonia, Bacterial meningitis, Bacterial septicemia, Skin and soft tissue infections, Osteomyelitis (Bone and joint infection), Intraabdominal infection, Bacteremia, Bacterial endocarditis and Pyelonephritis.
• Cefepime 1gm is a fourth-generation cephalosporin antibiotic used to treat bacterial infections. It blocks the bacterial cell wall synthesis which is essential for bacterial growth.
• This medicine is not used for common flu and cold symptoms. And not treat viral infections. This medicine is commonly prescribed for cough and colds caused by bacterial and parasitic infections.
• This medicine is contraindicated to allergic symptoms such as skin rash, itching, swelling and breathing difficulties.