Drug Interaction of Septran DS Tablet
BCG vaccine live
The use of this medicine is contraindicated because the use of trimethoprim decreases the effect of the BCG vaccine live by pharmacodynamic antagonism
Use alternative drugs because the use of abametapir will increase the effect of trimetho[rim by affecting its hepatic and intestinal enzyme metabolism.
Use alternative drug because the combination of this drug increases the QTc interval
Use alternative drugs because the use of sulfamethoxazole increases the effect of antithrombin 111 by plasma protein binding competition.
Therapy should be administered with caution because the combination of this drug increases the serum potassium level and it also decreases the urinary potassium excretion
Therapy should be administered with caution because the use of cimetidine increases the effect of sulfamethoxazole by basic drug competition for renal tubular clearance.
Use of alcohol with sulfamethoxazole produces unpleasant side effects such as fast heartbeat, redness under your skin, tingly feeling, nausea, vomiting.
This medicine kills the good helpful bacteria in your stomach or intestine and causes diarrhea. This drug should be used caution in patients with gastrointestinal disease, especially colitis (swelling of the colon inner lining). It leads to worsening the patient’s health condition.
Therapy should be administered with caution in patients who are having blood dyscrasias or bone marrow suppression because the use of sulfonamides may cause hematologic toxicity including methemoglobinemia, leucopenia, granulocytopenia, eosinophilia, hemolytic anemia, aplastic anemia, purpura, thrombocytopenia, and hypoprothrombinemia.
Therapy should be administered with caution in patients with hepatic impairment because the use of sulfonamides may cause hepatotoxicity including jaundice, diffuse hepatocellular necrosis, hepatitis, and hepatic failure
Therapy should be administered with caution in patients with urinary obstruction because the use of sulfonamides `increase the risk for developing renal toxicity such as uro and nephrolithiasis, nephritis, toxic nephrosis, hematuria, proteinuria, and elevated BUN and creatinine
Using this medicine develops Crystalluria (precipitation of this drug occurs in the urinary tract), which leads to cloudy urine. Drink more liquids adequately to avoid this condition.