Brand Name Sippi 40mg Tablet
Salt Composition pantoprazole (40mg)
Strength 40mg
Product Form Tablet
Storage Store at room temperature (10-30°C)
Category Gastro Intestional Tract
Country of Origin India
Manufacturer Acceleration Organics Pvt Ltd
Manufacturer/Marketer AddressAcceleration Organics Pvt Ltd,7259, (Backside), Office No. 3 & 4, Prem Nagar, Shakti Nagar, Delhi 110007.
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M.R.P : Rs.49.00       Price : Rs.41.65

You Save : Rs.7.35    Inclusive of all taxes

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Availability : In Stock


    Medical Description of Sippi 40mg Tablet

    Sippi 40mg Tablet contains Pantoprazole 40mg. Pantoprazole is a proton pump inhibitors (PPIs), an anti-ulcer agent used to treat to stomach, and duodenal ulcers, gastroesophageal reflux disease (GERD), Erosive Esophagitis, Zollinger-Ellison syndrome. It decreases stomach acid secretion. It relieves ulcers caused by Helicobacter pylori infection, used in combination with antibiotics like amoxicillin, or clarithromycin, and metronidazole, or tinidazole. Furthermore, it is used to treats stress ulcers and acid secretion during the intake of painkillers (NSAIDs).

    This medicine is contraindicated to allergic symptoms such as skin rashes, itching, swelling, breathing difficulties, etc, liver dysfunction, vitamin, and mineral deficiency.


    Sippi 40mg Tablet Uses

    Used in the treatment of the following conditions as Erosive esophagitis, Gastroesophageal reflux disease, Helicobacter pylori infection, Zollinger-Ellison syndrome, and Gastroduodenal ulcers.


    Sippi 40mg Tablet Benefits

    Erosive esophagitis

    The swelling of the oesophagus (muscular tube that helps food moves from the throat to the stomach) is called Esophagitis. It is caused due to excess acid production back flow from stomach to oesophagus, resulting in a condition called Erosive esophagitis; it should irritate, and damages the lining of the oesophagus. This medicine is used to treat this acid suppression in the stomach.

    Gastroesophageal reflux disease (GERD)

    GERD occurs due to stomach acid frequently flows backwards direction from the stomach to the oesophagus, which leads to developing heartburn, and acid indigestion. Primarily it can manage lifestyle changes, and using OTC (Over the counter) medicines. Also, sometimes need surgery. This medicine is used to treat this backflow acid secretion in the stomach.

    Helicobacter pylori infection

    H. Pylori causes infection to the lining of the stomach called H. Pylori infection, gastritis, and peptic ulcer disease. This medicine is used in combination with antibiotics (amoxicillin, or clarithromycin), and metronidazole, or tinidazole to treat this bacterial infection.

    Zollinger-Ellison syndrome

    Tumours formed in the pancreas and duodenum leads to produce gastrin hormone, which in turn causes more acid secretion in the stomach is called Zollinger-Ellison syndrome. This medicine is used to treat this acid suppression in the stomach due to tumours.

    Gastro- duodenal ulcers

    By increasing stomach acid secretion leads to develop gastro-duodenal ulcers. This medicine is used to treat this excessive stomach acid production. Also used to treat stress ulcers.


    Sippi 40mg Tablet Indication

    Sippi 40mg Tablet is used in the treatment of the following conditions as Erosive esophagitis, Gastroesophageal reflux disease, Helicobacter pylori infection, Zollinger-Ellison syndrome, and Gastro- duodenal ulcers.

    Pantoprazole can also prescribe with the combination of antibiotics (amoxicillin, or clarithromycin), and metronidazole, or tinidazole to treat H. Pylori infection. Also used to treat stress ulcers, arises due to intake of NSAIDs. The course of this medicine is up to 8 weeks, infections not suppress, increase the course for more than 8 weeks in some cases. But, children should not be given more than 8 weeks. Swallow the whole tablet at once. Don’t break, chewed, or crushed the tablet.


    Mechanism of action of Sippi 40mg Tablet

    Sippi 40mg Tablet contains Pantoprazole 40mg. Pantoprazole acts on the final step of gastric acid secretion; it blocks the acid releasing gastric parietal cells of the stomach. A parietal cell of the stomach contains H+/K+ ATP Pumps, which helps in acid secretion and then inhibits acid production by blocking these H+K+ ATP pumps. This action will last up to 24 hours, in between; more pumps will be produced by the stomach, which indicates then

    need to take the next dose to prevent the acid production in the stomach.


    How Sippi 40mg Tablet works

    Pantoprazole is a proton pump inhibitor (PPI), works by inhibiting the action of proton pumps (presented in the parietal cells of the stomach, involves acid secretion). Then it decreases the acid secretion from the stomach


    Sippi 40mg Tablet Contraindication

    This medicine is contraindicated to allergic symptoms such as skin rashes, itching, swelling, breathing difficulties, etc, liver dysfunction, vitamin, and mineral deficiency.


    Sippi 40mg Tablet Side Effects

    • Nausea
    • Diarrhoea
    • Headache
    • Abdominal pain
    • Muscle pain
    • Joint pain
    • Dizziness
    • Rashes
    • Leucopenia
    • Hepatic dysfunction


    FAQs for Sippi 40mg Tablet

    Does Sippi 40mg (Pantoprazole 40mg) Tablet have a habit-forming drug?

    No, Sippi 40mg Tablet doesn’t have a habit-forming tendency.

    What is the time duration for Sippi 40mg Tablet to react on the body?

    Sippi 40mg Tablet shows its action within one hour after administration. It will take 2 to 3 days for better relief and 4 to 5 weeks will take for complete relief.

    How long Sippi 40mg Tablet will sustain in our body?

    Sippi 40mg Tablet remains for 24hrs in our body.

    Is it safe during pregnancy?

    Yes. Sippi 40mg Tablet is safe during pregnancy. Sippi 40mg Tablet doesn’t show an effect on the fetus. Ask your doctor, and then take for a better quality of life.

    Can we take over years of time?

    Long-term use of this medicine leads to develop vitamin, and mineral deficiencies. Ask your doctor, and then take for a better quality of life.


    Precautions and general warning of Sippi 40mg Tablet

    Alcohol

    No. It is not safe with alcohol consumption. It shows harmful effects. Ask your doctor, and then take for a better quality of life.

    Driving or operating machinery

    No. Sippi 40mg Tablet is not safe after administration. It causes vision disturbances, dizziness, and alters the ability to drive. Ask your doctor, and then take for a better quality of life.

    Pregnancy

    Yes. This tablet is safe during pregnancy. It doesn’t show an effect on the fetus. Ask your doctor, and then take for a better quality of life.

    Breast Feeding

    No. Sippi 40mg Tablet is not safe during breastfeeding. It passes through the breast milk and shows an effect on the babies. Ask your doctor, and then take for a better quality of life.

    Kidney Problem

    Yes. This tablet is safe in patients with kidney diseases. It doesn’t show an effect on the kidneys. Ask your doctor, and then take for a better quality of life.

    Liver Disease

    This tablet should be used with caution in patients with hepatic dysfunction; hepatic impairment, or liver diseases. Then it leads to the risk of liver dysfunction or liver damage. Inform your doctor, and then take for a better life. Based on the patient clinical conditions, dose adjustment or replacement is needed.


    How to Take Sippi 40mg Tablet

    This tablet should be taken on an empty stomach, at least one hour before the meal as prescribed by the doctor. Take this medicine at a fixed time intervals. It is better, try to finish your dinner three hours before going to bed, for reducing the acid secretion in the stomach.

    Take the correct dose and duration of medicine as prescribed by the doctor. Swallow whole tablet at once. Don’t break, chewed, or crushed the tablet.


    Use of Sippi 40mg Tablet in Adult

    It is considered safe to use this tablet in adult. Kindly consult with your doctor before initiating the treatment.


    Use of Sippi 40mg Tablet in children

    Information regarding the use of this tablet in children is not available. Kindly consult with your doctor


    Use of Sippi 40mg Tablet in Elderly Patients

    It is considered safe to use this tablet in an elderly patient if it is prescribed by your doctor                  


    Other general warnings

    If you are allergic to Pantoprazole. Informed the doctor before prescribing this medicine. If you noticed any allergic symptoms such as skin rashes, itching, swelling, breathing difficulties, etc. Immediately meet your doctor, for a better quality of a life.


    Talk to your doctor if

    • If you’re allergic to the composition of the medicines

    • If you’re using any concomitant medications

    • If you’re not responding to the treatment


    General instructions

    Sippi 40mg (Pantoprazole (40mg)) Tablet is used in the treatment of the following conditions as Erosive esophagitis, Gastroesophageal reflux disease, Helicobacter pylori infection, Zollinger-Ellison syndrome, and Gastro- duodenal ulcers.

    Pantoprazole can also prescribe with the combination of antibiotics (amoxicillin, or clarithromycin), and metronidazole, or tinidazole to treat H. Pylori infection. Also used to treat stress ulcers, arises due to intake of NSAIDs


    Drug Interaction of Sippi 40mg Tablet

    Drug-Drug Interaction

    Ketoconazole

    Ketoconazole is an antifungal drug used to treat fungal infections. This medicine alters the action of ketoconazole. Ask your doctor, and then take for the better quality of life.

    Methotrexate

    Methotrexate is an antimetabolite used to treat rheumatoid arthritis. This medicine alters the action of methotrexate. Ask your doctor, and then take for the better quality of life.

    Warfarin

    Warfarin is an anticoagulant drug. This medicine increases the levels of warfarin in our body leads to an increase in INR levels. It leads to risk of serious bleeding. Ask your doctor, and then take for a better quality of life.

    Nelfinavir

    Nelfinavir is an antiviral drug. This medicine alters the action of nelfinavir. Ask your doctor, and then take for a better quality of life.

    Digoxin

    Digoxin is a cardiac glycoside used to treat irregular heartbeats. This medicine alters the action of digoxin. Ask your doctor, and then take for a better quality of life.

    Drug-Food Interaction

    By using this medicine with food should be maintained time gap at least 1 hour before the meals for better effectiveness of the medicine. By using this medicine with spicy, fatty foods, alcohol, caffeinated drinks, or beverages such as coffee, tea, cola, etc, should be avoided for better effectiveness of the medicine.

    Drug-Disease Interaction

    Liver Disease

    Pantoprazole primarily conversation of its active form occurs in the liver. It should be used with caution in patients with hepatic dysfunction; hepatic impairment, or liver diseases. Then it leads to the risk of liver dysfunction or liver damage. Inform your doctor, and then take for a better life. Based on the patient clinical conditions, dose adjustment or replacement is needed.

    Colitis

    This drug should be used cautiously in patients with gastrointestinal disease, especially colitis (swelling of the colon inner lining). It leads to worsening the patient health conditions. Ask your doctor, and then take for a better quality of life.

    Osteoporosis

    It is a bone disease, becomes bones weak. Long-term use of pantoprazole can cause calcium deficiency, which leads to showing an effect on bones. Calcium and vitamin D supplements are given with pantoprazole to minimize this calcium and vitamin deficiency. Ask your doctor, and then take for a better quality of life.

    Lupus erythematous

    By using this medicine leads to develop lupus erythematous (an autoimmune disease that forms lupus, which affects the joints, brain, kidneys, akin, and other organs), leads to developing tiredness, joint pain, rashes, or lesions on the skin. Inform your doctor, and then take for a better life. Based on the patient clinical conditions, dose adjustment or replacement is needed.

    Bone fractures

    By long-term use of this medicine leads to the development of bone fractures (occurs due to deficiency of calcium supplement). Calcium and vitamin D supplements are given with pantoprazole to minimize this calcium and vitamin deficiency. Ask your doctor, and then take for a better quality of life.

    Vitamin B12 deficiency

    By long-term use of this medicine leads to develop vitamin B12 deficiency. Vitamin B12 supplements are given with pantoprazole to minimize this vitamin deficiency. Ask your doctor, and then take for a better quality of life.

    Hypomagnesemia

    By long-term use of this medicine leads to develop hypomagnesemia (low magnesium levels), which leads to developing dizziness, shivering, muscle pain, irregular heartbeat, seizures, or fits. Inform your doctor, and then take for a better life. Based on the patient clinical conditions, dose adjustment or replacement is needed


    Over Dose

    Take the doses properly as directed by the doctor. Do not be taken as an overdose. If you are taken, unfortunately, immediately meet the doctor, for a better quality of life.


    Missed Dose

    Probably do not skip the dose of pantoprazole as directed by the doctor. If you skipped the dose, take it immediately. If you skipped the dose, it’s nearer to the next dose, take properly one dose, do not be taken as double the dose. It leads to overdose, immediately meet the doctor, for a better life.


    Storage and Disposal

    Stored at 10-30°C room temperature.

    Protect from light and heat.

    Keep away from children and pets. Otherwise, it becomes toxic to them.

    Disposed of properly in a suitable bag.


    Fast Tag

    Sippi 40mg (Pantoprazole 40mg) Tablet contains Pantoprazole 40mg.

    Pantoprazole is a proton pump inhibitors (PPI), an anti-ulcer agent used to treat to stomach, and duodenal ulcers, gastroesophageal reflux disease (GERD), Erosive Esophagitis, Zollinger-Ellison syndrome.

    It decreases stomach acid secretion. It relieves ulcers caused by Helicobacter pylori infection, used in combination with antibiotics like amoxicillin, or clarithromycin, and metronidazole, or tinidazole.

    Furthermore, it is used to treat stress ulcers and acid secretion during the intake of painkillers (NSAIDs).

    Likewise, it is better, try to finish your dinner three hours before going to bed, for reducing the acid secretion in the stomach.


    References

    1. KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 651-653.
    2. Wallace JL, Sharkey KA. Pharmacotherapy of Gastric Acidity, Peptic Ulcers, and Gastroesophageal Reflux Disease. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman's: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: The McGraw-Hill Companies; 2011. pp. 1203-04.
    3. Pubchem.ncbi.nlm.nih.gov. 2021. Pantoprazole. [online] Available at: < [Accessed 13 January 2021]. https://pubchem.ncbi.nlm.nih.gov/compound/4679>
    4. Accessdata.fda.gov. 2021. [online] Available at: < [Accessed 13 January 2021]. http://www.accessdata.fda.gov/drugsatfda_docs/label/2012/020987s045lbl.pdf>
    5. Medicines.org.uk. 2021. Pantoprazole 40 Mg Gastro-Resistant Tablets - Patient Information Leaflet (PIL) - (Emc). [online] Available at: < [Accessed 13 January 2021].https://www.medicines.org.uk/emc/product/484/pil>
    6. Go.drugbank.com. 2021. Pantoprazole | Drugbank Online. [online] Available at: < [Accessed 13 January 2021]. https://go.drugbank.com/drugs/DB00213>