Sitazit M 50mg/1000mg Tablet
Brand Name | Sitazit M 50mg/1000mg Tablet |
Salt Composition |
Sitagliptin (50mg) + Metformin (1000mg) |
Strength | 50mg + 1000mg |
Product Form | Tablet |
Pack | 10 Tablet(s) in Strip |
Storage | Store below 30°C |
Category |
Antidiabetic |
SubCategory |
anti-diabetic |
Country of Origin | India |
Manufacturer |
Glenmark Pharmaceuticals Ltd |
Manufacturer/Marketer Address | Glenmark Pharmaceuticals Limited, B/2, Mahalaxmi Chambers, 22, Bhulabhai Desai Road, Mumbai – 400 026. |
You Save : Rs.29.00 Inclusive of all taxes
- Do not take this medicine if you are allergic to Sitagliptin and Metformin
- It is contraindicated to use this medicine in patients with a history of severe kidney impairment, acute or chronic metabolic acidosis
- Stomach pain
- Diarrhea
- Hypoglycemia
- Vomiting
- Lactic acidosis
- Upper respiratory tract infection
- Mouth ulcer
- Decreased appetite
- Is the Sitazit M 50mg/1000mg Tablet safe?
- Is an Sitazit M 50mg/1000mg Tablet bad for kidneys?
- Does the Sitazit M 50mg/1000mg Tablet cause hypoglycemia?
- Lactic acidosis may occur due to metformin accumulation
- acute pancreatitis, acute renal failure, and allergic reaction were reported while you are receiving this medicine
- Heart failure has been observed while you are receiving this medicine
- You have a history of gastrointestinal disease
- You are not responding to the treatment
- You have experienced any allergic reactions like rashes and itching
- You have watery diarrhea, stomach pain, and fever
- Stored at 30°C at room temperature.
- Protect from light and heat.
- Keep away from children and pets. Otherwise, it becomes toxic to them.
- Disposed of properly in a suitable bag.
- Sitazit M 50mg/1000mg Tablet contains Sitagliptin 50mg and Metformin 1000mg is a combination of two antidiabetic agents used to treat type 2 diabetes mellitus in adults.
- This also helps to prevent serious complications of diabetes like kidney damage and blindness.
- It produces its action by lowering the blood sugar level by increasing the amount of insulin that is released by the pancreas and liver.
- Carry some sugary food or fruit juice with you if you have to experience hypoglycaemic symptoms such as cold sweets, cool pale skin, tremors, and anxiety
- Kindly monitor your liver function while you are receiving this medicine
- Inform your doctor if you have developed symptoms such as abdominal pain, loss of appetite, and jaundice
Medical Description of Sitazit M 50mg/1000mg Tablet
Sitazit M 50mg/1000mg Tablet contains Sitagliptin 50mg and Metformin 1000mg is a combination of two antidiabetic agents used to treat type 2 diabetes mellitus in adults. This also helps to prevent serious complications of diabetes like kidney damage and blindness. It produces its action by lowering the blood sugar level by increasing the amount of insulin that is released by the pancreas and liver. It also helps to reduce the risk of having a heart attack or stroke.
Sitazit M 50mg/1000mg Tablet Uses
It is used in the treatment of the following condition type 2 diabetes mellitus
Sitazit M 50mg/1000mg Tablet Benefits
Type 2 diabetes mellitus
It is also called adult-onset diabetes. It is a chronic condition in which our body does not produce enough insulin or resist insulin and it may increase the risk of cardiovascular diseases like chest pain and heart attack.
Sitazit M 50mg/1000mg Tablet Indication
The Sitazit M 50mg/1000mg Tablet contains Sitagliptin 50mg and Metformin 1000mg is prescribed for the following indications as type 2 diabetes mellitus.
Mechanism of action of Sitazit M 50mg/1000mg Tablet
Sitazit M 50mg/1000mg Tablet contains Sitagliptin 50mg and Metformin 1000mg is a combination of two anti-diabetic agents. Sitagliptin 100mg is a dipeptidyl peptidase-IV inhibitor that produces its action by increasing the release of insulin from the pancreas and decreasing the hormone that raises blood sugar levels.
Metformin 1000mg is a biguanide that produces its action by lowering the glucose production in the liver and delay the glucose absorption from the intestine and it also increases the body's sensitivity to insulin.
How Sitazit M 50mg/1000mg Tablet works
Sitazit M 50mg/1000mg Tablet contains Sitagliptin 50mg and Metformin 1000mg is a combination of two anti-diabetic agents. Sitagliptin (100mg) is a dipeptidyl peptidase-IV inhibitor that produces its action by increasing the release of insulin from the pancreas and decreasing the hormone that raises blood sugar levels.
Metformin (1000mg) is a biguanide that produces its action by lowering the glucose production in the liver and delay the glucose absorption from the intestine and it also increases the body's sensitivity to insulin.
Sitazit M 50mg/1000mg Tablet Contraindication
Sitazit M 50mg/1000mg Tablet Side Effects
FAQs for Sitazit M 50mg/1000mg Tablet
Yes, the use of this medicine is considered safe if you use this medicine as per the dose and duration advice by your doctor.
No, this medicine is not harmful if your kidney function is normal. If you have kidney problems you will be started at a lower dose
Yes, the use of this medicine leads to hypoglycemia this usually occurs when you skip your meal after taking the medication.
Precautions and general warning of Sitazit M 50mg/1000mg Tablet
Alcohol
It is considered unsafe to consume alcohol while taking this medication. Kindly consult with your doctor
Driving or operating machinery
It is considered unsafe to drive while you are receiving this medicine. Kindly consult with your doctor.
Pregnancy
It is considered unsafe during pregnancy because it may produce harmful effects on the fetus. Kindly consult with your doctor.
Breast Feeding
It is considered unsafe during breastfeeding because it may excrete via breast milk. Kindly consult with your doctor.
Kidney Problem
This medicine should be used with caution in patients with kidney impairment. The use of this medicine required dose modification. Kindly consult with your doctor.
Liver Disease
It is considered unsafe to use this medicine in patients with liver impairment. Kindly consult with your doctor.
How to Take Sitazit M 50mg/1000mg Tablet
The tablet is taken orally on an empty stomach. You should not chew, cut or crush the tablet. Take this medicine as per the dose and duration advised by your doctor. Follow the direction mentioned within the label if you probably did not understand the appliance kindly ask your doctor or pharmacist to elucidate in detail. Do not withdraw the medicine when you feel better kindly complete the course of treatment to avoid reoccurrence.
Use of Sitazit M 50mg/1000mg Tablet in Adult
It is considered to be safe to use this medicine in an adult patient if the medicine is prescribed by a doctor. Kindly consult with your doctor.
Use of Sitazit M 50mg/1000mg Tablet in children
Safety and efficacy were not established in children. Kindly consult with your doctor.
Use of Sitazit M 50mg/1000mg Tablet in Elderly Patients
Sitazit M 50mg/1000mg Tablets should be used with caution in patients in an elderly age group, which leads to developing further medical problems, leads to worsening the patient's health conditions. Kindly consult with your doctor. Dose modification or replacement is required based on the medical conditions of the patient.
Other general warnings
Talk to your doctor if
General instructions
Sitagliptin 50mg and Metformin 1000mg are a combination of two antidiabetic agents used to treat type 2 diabetes mellitus in adults. This also helps to prevent serious complications of diabetes like kidney damage and blindness. It produces its action by lowering the blood sugar level by increasing the amount of insulin that is released by the pancreas and liver. It also helps to reduce the risk of having a heart attack or stroke.
Drug Interaction of Sitazit M 50mg/1000mg Tablet
Drug-Drug Interaction
Ethanol + Metformin
Ethanol increases the toxicity of metformin by others. More consumption of ethanol may alter glycemic control and may produce a disulfiram-like reaction. It is contraindicated to use.
Ranolazine + Metformin
Use alternative drugs because the use of Ranolazine increases the effect of metformin by decreasing its elimination.
Tranylcypromine + Metformin
Use an alternative drug because the use of Tranylcypromine will increase the effect of metformin by an unspecified interaction mechanism.
Acetazolamide + Metformin
Closely monitor the patient serum bicarbonate level because the use of Acetazolamide increases the toxicity of metformin by others.
Amiodarone + Metformin
Therapy should be administered with caution because the use of amiodarone increases the effect of metformin by cationic drug competition for renal tubular clearance.
Betamethasone + Metformin
Therapy should be administered with caution because the use of betamethasone decreases the effect of metformin by pharmacodynamic antagonism.
Ethanol + Sitagliptin
Ethanol increases the toxicity of Sitagliptin by others. More consumption of ethanol may alter glycemic control and may produce a disulfiram-like reaction. It is contraindicated to use
Efavirenz + Sitagliptin
Use alternative drugs because the use of Efavirenz increases the effect of Sitagliptin by affecting the hepatic enzyme.
Bexarotene + Sitagliptin
Therapy should be administered with caution because the use of Bexarotene increases the effect of Sitagliptin by pharmacodynamic synergism.
Fluoxetine + Sitagliptin
Use an alternative drug because the use of Fluoxetine increases the effect of Sitagliptin by affecting the hepatic enzyme.
Drug-Food Interaction
Alcohol may affect the patient blood sugar level either by increasing or by decreasing it depends upon the amount you have consumed and it also causes lactic acidosis. Avoid drinking alcohol when you are having diabetes
Drug-Disease Interaction
Cardiovascular risk + Metformin
The use of anti-diabetic drugs may increase the risk of cardiovascular mortality rate when compared with a diet or diet with insulin. Kindly monitor the patient cardiac function
Lactic acidosis + Metformin
The use of Metformin in a patient who is having renal dysfunction, liver disease, congestive heart failure, dehydration, shock, and myocardial infarction may lead to developing lactic acidosis. Kindly use it with caution.
Hypoglycemia + Metformin
During anti-diabetic medication, patients can experience hypoglycemia. Use with caution the patient who is having adrenal insufficiency, autonomic neuropathy, and receiving a beta-adrenergic blocking agent
Vitamin B12 deficiency + Metformin
Prolonged use of metformin can interfere with the absorption of vitamin b12 in the stomach. It may lead to anemia, tingling sensation, numbness in hands and feet, and ataxia. To avoid this effect kindly take the vitamin b12 from outside sources once a year
Pancreatitis + Sitagliptin
Therapy should be administered with caution in patients with pancreatitis because the use of this medicine associated with acute pancreatitis
Renal dysfunction + Sitagliptin
Therapy should be administered with caution in patients with renal impairment because the use of this medicine may cause acute renal failure
Over Dose
Take the medicine as directed by the doctor don’t overdose on the medicine. If you have taken an overdose on this medicine immediately meet the doctor and rush to the nearby hospital.
Missed Dose
Take the medicine as directed by the doctor. Do not skip the medicine, if you forgot to take the medicine or missed the dose. It is almost time for your next dose, skip the missed dose and go back to your regular schedule. Don’t take the extra dose take the regular dose immediately. Don’t use the two-dose at one time (Double Dose).
Storage and Disposal
Fast Tag