Sitazit-M 50mg/500mg Tablet

Brand Name Sitazit-M 50mg/500mg Tablet
Salt Composition

Sitagliptin (50mg) + Metformin (500mg)

Sitagliptin (50mg) + Metformin (500mg)

Strength 50mg + 500mg
Product Form Tablet
Pack 15 Tablet(s) in Strip
Storage Store below 30°C
Category

Antidiabetic

SubCategory

anti-diabetic

Country of Origin India
Manufacturer

Glenmark Pharmaceuticals Ltd

Manufacturer/Marketer Address Glenmark Pharmaceuticals Limited, B/2, Mahalaxmi Chambers, 22, Bhulabhai Desai Road, Mumbai – 400 026.
-20%
image
M.R.P : Rs.125.00       Price : Rs.100.00

You Save : Rs.25.00    Inclusive of all taxes

- +
15 Tablet(s) in Strip

Availability : In Stock

  Online Payment Only

  Non Returnable Read More



    Medical Description of Sitazit-M 50mg/500mg Tablet

    Sitazit-M 50mg/500mg Tablet contains Sitagliptin 50mg and Metformin 500mg is a combination of two antidiabetic agents used to treat type 2 diabetes mellitus in adults. This also helps to prevent serious complications of diabetes like kidney damage and blindness. It produces its action by lowering the blood sugar level by increasing the amount of insulin that is released by the pancreas and liver. It also helps to reduce the risk of having a heart attack or stroke.


    Sitazit-M 50mg/500mg Tablet Uses

    It is used in the treatment of the following condition type 2 diabetes mellitus


    Sitazit-M 50mg/500mg Tablet Benefits

    Type 2 diabetes mellitus

    It is also called adult-onset diabetes. It is a chronic condition in which our body does not produce enough insulin or resist insulin and it may increase the risk of cardiovascular diseases like chest pain and heart attack.


    Sitazit-M 50mg/500mg Tablet Indication

    The Sitazit-M 50mg/500mg Tablet contains Sitagliptin 50mg and Metformin 500mg is prescribed for the following indications as type 2 diabetes mellitus.


    Mechanism of action of Sitazit-M 50mg/500mg Tablet

    Sitazit-M 50mg/500mg Tablet contains Sitagliptin 50mg and Metformin 500mg is a combination of two anti-diabetic agents. Sitagliptin 100mg is a dipeptidyl peptidase-IV inhibitor that produces its action by increasing the release of insulin from the pancreas and decreasing the hormone that raises blood sugar levels.

    Metformin 500mg is a biguanide that produces its action by lowering the glucose production in the liver and delay the glucose absorption from the intestine and it also increases the body's sensitivity to insulin.


    How Sitazit-M 50mg/500mg Tablet works

    Sitazit-M 50mg/500mg Tablet contains Sitagliptin 50mg and Metformin 500mg is a combination of two anti-diabetic agents. Sitagliptin (100mg) is a dipeptidyl peptidase-IV inhibitor that produces its action by increasing the release of insulin from the pancreas and decreasing the hormone that raises blood sugar levels.

    Metformin (500mg) is a biguanide that produces its action by lowering the glucose production in the liver and delay the glucose absorption from the intestine and it also increases the body's sensitivity to insulin.


    Sitazit-M 50mg/500mg Tablet Contraindication

    • Do not take this medicine if you are allergic to Sitagliptin and Metformin
    • It is contraindicated to use this medicine in patients with a history of severe kidney impairment, acute or chronic metabolic acidosis


    Sitazit-M 50mg/500mg Tablet Side Effects

    • Stomach pain
    • Diarrhea
    • Hypoglycemia
    • Vomiting
    • Lactic acidosis
    • Upper respiratory tract infection
    • Mouth ulcer
    • Decreased appetite


    FAQs for Sitazit-M 50mg/500mg Tablet

    • Is the Sitazit-M 50mg/500mg Tablet safe?

    Yes, the use of this medicine is considered safe if you use this medicine as per the dose and duration advice by your doctor.

    • Is an Sitazit-M 50mg/500mg Tablet bad for kidneys?

    No, this medicine is not harmful if your kidney function is normal. If you have kidney problems you will be started at a lower dose

    • Does the Sitazit-M 50mg/500mg Tablet cause hypoglycemia?

    Yes, the use of this medicine leads to hypoglycemia this usually occurs when you skip your meal after taking the medication.


    Precautions and general warning of Sitazit-M 50mg/500mg Tablet

    Alcohol

    It is considered unsafe to consume alcohol while taking this medication. Kindly consult with your doctor

    Driving or operating machinery

    It is considered unsafe to drive while you are receiving this medicine. Kindly consult with your doctor.

    Pregnancy

    It is considered unsafe during pregnancy because it may produce harmful effects on the fetus. Kindly consult with your doctor.

    Breast Feeding

    It is considered unsafe during breastfeeding because it may excrete via breast milk. Kindly consult with your doctor.

    Kidney Problem

    This medicine should be used with caution in patients with kidney impairment. The use of this medicine required dose modification. Kindly consult with your doctor.         

    Liver Disease

    It is considered unsafe to use this medicine in patients with liver impairment. Kindly consult with your doctor.


    How to Take Sitazit-M 50mg/500mg Tablet

    The tablet is taken orally on an empty stomach. You should not chew, cut or crush the tablet. Take this medicine as per the dose and duration advised by your doctor. Follow the direction mentioned within the label if you probably did not understand the appliance kindly ask your doctor or pharmacist to elucidate in detail. Do not withdraw the medicine when you feel better kindly complete the course of treatment to avoid reoccurrence.


    Use of Sitazit-M 50mg/500mg Tablet in Adult

    It is considered to be safe to use this medicine in an adult patient if the medicine is prescribed by a doctor. Kindly consult with your doctor.


    Use of Sitazit-M 50mg/500mg Tablet in children

    Safety and efficacy were not established in children. Kindly consult with your doctor.


    Use of Sitazit-M 50mg/500mg Tablet in Elderly Patients

    Sitazit-M 50mg/500mg Tablets should be used with caution in patients in an elderly age group, which leads to developing further medical problems, leads to worsening the patient's health conditions. Kindly consult with your doctor. Dose modification or replacement is required based on the medical conditions of the patient.


    Other general warnings

    • Lactic acidosis may occur due to metformin accumulation
    • acute pancreatitis, acute renal failure, and allergic reaction were reported while you are receiving this medicine
    • Heart failure has been observed while you are receiving this medicine


    Talk to your doctor if

    • You have a history of gastrointestinal disease
    • You are not responding to the treatment
    • You have experienced any allergic reactions like rashes and itching
    • You have watery diarrhea, stomach pain, and fever


    General instructions

    Sitagliptin 50mg and Metformin 500mg are a combination of two antidiabetic agents used to treat type 2 diabetes mellitus in adults. This also helps to prevent serious complications of diabetes like kidney damage and blindness. It produces its action by lowering the blood sugar level by increasing the amount of insulin that is released by the pancreas and liver. It also helps to reduce the risk of having a heart attack or stroke.


    Drug Interaction of Sitazit-M 50mg/500mg Tablet

    Drug-Drug Interaction

    Ethanol + Metformin

    Ethanol increases the toxicity of metformin by others. More consumption of ethanol may alter glycemic control and may produce a disulfiram-like reaction. It is contraindicated to use.

    Ranolazine + Metformin

    Use alternative drugs because the use of Ranolazine increases the effect of metformin by decreasing its elimination.

    Tranylcypromine + Metformin

    Use an alternative drug because the use of Tranylcypromine will increase the effect of metformin by an unspecified interaction mechanism.

    Acetazolamide + Metformin

    Closely monitor the patient serum bicarbonate level because the use of Acetazolamide increases the toxicity of metformin by others.

    Amiodarone + Metformin

    Therapy should be administered with caution because the use of amiodarone increases the effect of metformin by cationic drug competition for renal tubular clearance.

    Betamethasone + Metformin

    Therapy should be administered with caution because the use of betamethasone decreases the effect of metformin by pharmacodynamic antagonism.

    Ethanol + Sitagliptin

    Ethanol increases the toxicity of Sitagliptin by others. More consumption of ethanol may alter glycemic control and may produce a disulfiram-like reaction. It is contraindicated to use

    Efavirenz + Sitagliptin

    Use alternative drugs because the use of Efavirenz increases the effect of Sitagliptin by affecting the hepatic enzyme.

    Bexarotene + Sitagliptin

    Therapy should be administered with caution because the use of Bexarotene increases the effect of Sitagliptin by pharmacodynamic synergism.

    Fluoxetine + Sitagliptin

    Use an alternative drug because the use of Fluoxetine increases the effect of Sitagliptin by affecting the hepatic enzyme.

    Drug-Food Interaction

    Alcohol may affect the patient blood sugar level either by increasing or by decreasing it depends upon the amount you have consumed and it also causes lactic acidosis. Avoid drinking alcohol when you are having diabetes

    Drug-Disease Interaction

    Cardiovascular risk + Metformin

    The use of anti-diabetic drugs may increase the risk of cardiovascular mortality rate when compared with a diet or diet with insulin. Kindly monitor the patient cardiac function

    Lactic acidosis + Metformin           

    The use of Metformin in a patient who is having renal dysfunction, liver disease, congestive heart failure, dehydration, shock, and myocardial infarction may lead to developing lactic acidosis. Kindly use it with caution.

    Hypoglycemia + Metformin

    During anti-diabetic medication, patients can experience hypoglycemia. Use with caution the patient who is having adrenal insufficiency, autonomic neuropathy, and receiving a beta-adrenergic blocking agent

    Vitamin B12 deficiency + Metformin

    Prolonged use of metformin can interfere with the absorption of vitamin b12 in the stomach. It may lead to anemia, tingling sensation, numbness in hands and feet, and ataxia. To avoid this effect kindly take the vitamin b12 from outside sources once a year

    Pancreatitis + Sitagliptin

    Therapy should be administered with caution in patients with pancreatitis because the use of this medicine associated with acute pancreatitis

    Renal dysfunction + Sitagliptin

    Therapy should be administered with caution in patients with renal impairment because the use of this medicine may cause acute renal failure


    Over Dose

    Take the medicine as directed by the doctor don’t overdose on the medicine. If you have taken an overdose on this medicine immediately meet the doctor and rush to the nearby hospital.


    Missed Dose

    Take the medicine as directed by the doctor. Do not skip the medicine, if you forgot to take the medicine or missed the dose. It is almost time for your next dose, skip the missed dose and go back to your regular schedule. Don’t take the extra dose take the regular dose immediately. Don’t use the two-dose at one time (Double Dose).


    Storage and Disposal

    • Stored at 30°C at room temperature.
    • Protect from light and heat.
    • Keep away from children and pets. Otherwise, it becomes toxic to them.
    • Disposed of properly in a suitable bag.


    Fast Tag

    • Sitazit-M 50mg/500mg Tablet contains Sitagliptin 50mg and Metformin 500mg is a combination of two antidiabetic agents used to treat type 2 diabetes mellitus in adults.
    • This also helps to prevent serious complications of diabetes like kidney damage and blindness.
    • It produces its action by lowering the blood sugar level by increasing the amount of insulin that is released by the pancreas and liver.
    • Carry some sugary food or fruit juice with you if you have to experience hypoglycaemic symptoms such as cold sweets, cool pale skin, tremors, and anxiety
    • Kindly monitor your liver function while you are receiving this medicine
    • Inform your doctor if you have developed symptoms such as abdominal pain, loss of appetite, and jaundice







Sitazit M 50mg/500mg Tablet

Brand Name Sitazit M 50mg/500mg Tablet
Salt Composition
Strength 50mg + 500mg
Category

Antidiabetic

SubCategory

anti-diabetic

Country of Origin India
-20%
image
M.R.P : Rs.125.00       Price : Rs.100.00

You Save : Rs.25.00    Inclusive of all taxes

- +

Availability : In Stock

  Online Payment Only

  Non Returnable Read More



    Medical Description of Sitazit M 50mg/500mg Tablet

    Sitazit M 50mg/500mg Tablet contains Sitagliptin 50mg and Metformin 500mg is a combination of two antidiabetic agents used to treat type 2 diabetes mellitus in adults. This also helps to prevent serious complications of diabetes like kidney damage and blindness. It produces its action by lowering the blood sugar level by increasing the amount of insulin that is released by the pancreas and liver. It also helps to reduce the risk of having a heart attack or stroke.


    Sitazit M 50mg/500mg Tablet Uses

    It is used in the treatment of the following condition type 2 diabetes mellitus


    Sitazit M 50mg/500mg Tablet Benefits

    Type 2 diabetes mellitus

    It is also called adult-onset diabetes. It is a chronic condition in which our body does not produce enough insulin or resist insulin and it may increase the risk of cardiovascular diseases like chest pain and heart attack.


    Sitazit M 50mg/500mg Tablet Indication

    The Sitazit M 50mg/500mg Tablet contains Sitagliptin 50mg and Metformin 500mg is prescribed for the following indications as type 2 diabetes mellitus.


    Mechanism of action of Sitazit M 50mg/500mg Tablet

    Sitazit M 50mg/500mg Tablet contains Sitagliptin 50mg and Metformin 500mg is a combination of two anti-diabetic agents. Sitagliptin 100mg is a dipeptidyl peptidase-IV inhibitor that produces its action by increasing the release of insulin from the pancreas and decreasing the hormone that raises blood sugar levels.

    Metformin 500mg is a biguanide that produces its action by lowering the glucose production in the liver and delay the glucose absorption from the intestine and it also increases the body's sensitivity to insulin.


    How Sitazit M 50mg/500mg Tablet works

    Sitazit M 50mg/500mg Tablet contains Sitagliptin 50mg and Metformin 500mg is a combination of two anti-diabetic agents. Sitagliptin (100mg) is a dipeptidyl peptidase-IV inhibitor that produces its action by increasing the release of insulin from the pancreas and decreasing the hormone that raises blood sugar levels.

    Metformin (500mg) is a biguanide that produces its action by lowering the glucose production in the liver and delay the glucose absorption from the intestine and it also increases the body's sensitivity to insulin.


    Sitazit M 50mg/500mg Tablet Contraindication

    • Do not take this medicine if you are allergic to Sitagliptin and Metformin
    • It is contraindicated to use this medicine in patients with a history of severe kidney impairment, acute or chronic metabolic acidosis


    Sitazit M 50mg/500mg Tablet Side Effects

    • Stomach pain
    • Diarrhea
    • Hypoglycemia
    • Vomiting
    • Lactic acidosis
    • Upper respiratory tract infection
    • Mouth ulcer
    • Decreased appetite


    FAQs for Sitazit M 50mg/500mg Tablet

    • Is the Sitazit M 50mg/500mg Tablet safe?

    Yes, the use of this medicine is considered safe if you use this medicine as per the dose and duration advice by your doctor.

    • Is an Sitazit M 50mg/500mg Tablet bad for kidneys?

    No, this medicine is not harmful if your kidney function is normal. If you have kidney problems you will be started at a lower dose

    • Does the Sitazit M 50mg/500mg Tablet cause hypoglycemia?

    Yes, the use of this medicine leads to hypoglycemia this usually occurs when you skip your meal after taking the medication.


    Precautions and general warning of Sitazit M 50mg/500mg Tablet

    Alcohol

    It is considered unsafe to consume alcohol while taking this medication. Kindly consult with your doctor

    Driving or operating machinery

    It is considered unsafe to drive while you are receiving this medicine. Kindly consult with your doctor.

    Pregnancy

    It is considered unsafe during pregnancy because it may produce harmful effects on the fetus. Kindly consult with your doctor.

    Breast Feeding

    It is considered unsafe during breastfeeding because it may excrete via breast milk. Kindly consult with your doctor.

    Kidney Problem

    This medicine should be used with caution in patients with kidney impairment. The use of this medicine required dose modification. Kindly consult with your doctor.

    Liver Disease

    It is considered unsafe to use this medicine in patients with liver impairment. Kindly consult with your doctor.


    How to Take Sitazit M 50mg/500mg Tablet

    The tablet is taken orally on an empty stomach. You should not chew, cut or crush the tablet. Take this medicine as per the dose and duration advised by your doctor. Follow the direction mentioned within the label if you probably did not understand the appliance kindly ask your doctor or pharmacist to elucidate in detail. Do not withdraw the medicine when you feel better kindly complete the course of treatment to avoid reoccurrence.


    Use of Sitazit M 50mg/500mg Tablet in Adult

    It is considered to be safe to use this medicine in an adult patient if the medicine is prescribed by a doctor. Kindly consult with your doctor.


    Use of Sitazit M 50mg/500mg Tablet in children

    Safety and efficacy were not established in children. Kindly consult with your doctor.


    Use of Sitazit M 50mg/500mg Tablet in Elderly Patients

    Sitazit M 50mg/500mg Tablets should be used with caution in patients in an elderly age group, which leads to developing further medical problems, leads to worsening the patient's health conditions. Kindly consult with your doctor. Dose modification or replacement is required based on the medical conditions of the patient.


    Other general warnings

    • Lactic acidosis may occur due to metformin accumulation
    • acute pancreatitis, acute renal failure, and allergic reaction were reported while you are receiving this medicine
    • Heart failure has been observed while you are receiving this medicine


    Talk to your doctor if

    • You have a history of gastrointestinal disease
    • You are not responding to the treatment
    • You have experienced any allergic reactions like rashes and itching
    • You have watery diarrhea, stomach pain, and fever


    General instructions

    Sitagliptin 50mg and Metformin 500mg are a combination of two antidiabetic agents used to treat type 2 diabetes mellitus in adults. This also helps to prevent serious complications of diabetes like kidney damage and blindness. It produces its action by lowering the blood sugar level by increasing the amount of insulin that is released by the pancreas and liver. It also helps to reduce the risk of having a heart attack or stroke.


    Drug Interaction of Sitazit M 50mg/500mg Tablet

    Drug-Drug Interaction

    Ethanol + Metformin

    Ethanol increases the toxicity of metformin by others. More consumption of ethanol may alter glycemic control and may produce a disulfiram-like reaction. It is contraindicated to use.

    Ranolazine + Metformin

    Use alternative drugs because the use of Ranolazine increases the effect of metformin by decreasing its elimination.

    Tranylcypromine + Metformin

    Use an alternative drug because the use of Tranylcypromine will increase the effect of metformin by an unspecified interaction mechanism.

    Acetazolamide + Metformin

    Closely monitor the patient serum bicarbonate level because the use of Acetazolamide increases the toxicity of metformin by others.

    Amiodarone + Metformin

    Therapy should be administered with caution because the use of amiodarone increases the effect of metformin by cationic drug competition for renal tubular clearance.

    Betamethasone + Metformin

    Therapy should be administered with caution because the use of betamethasone decreases the effect of metformin by pharmacodynamic antagonism.

    Ethanol + Sitagliptin

    Ethanol increases the toxicity of Sitagliptin by others. More consumption of ethanol may alter glycemic control and may produce a disulfiram-like reaction. It is contraindicated to use

    Efavirenz + Sitagliptin

    Use alternative drugs because the use of Efavirenz increases the effect of Sitagliptin by affecting the hepatic enzyme.

    Bexarotene + Sitagliptin

    Therapy should be administered with caution because the use of Bexarotene increases the effect of Sitagliptin by pharmacodynamic synergism.

    Fluoxetine + Sitagliptin

    Use an alternative drug because the use of Fluoxetine increases the effect of Sitagliptin by affecting the hepatic enzyme.

    Drug-Food Interaction

    Alcohol may affect the patient blood sugar level either by increasing or by decreasing it depends upon the amount you have consumed and it also causes lactic acidosis. Avoid drinking alcohol when you are having diabetes

    Drug-Disease Interaction

    Cardiovascular risk + Metformin

    The use of anti-diabetic drugs may increase the risk of cardiovascular mortality rate when compared with a diet or diet with insulin. Kindly monitor the patient cardiac function

    Lactic acidosis + Metformin           

    The use of Metformin in a patient who is having renal dysfunction, liver disease, congestive heart failure, dehydration, shock, and myocardial infarction may lead to developing lactic acidosis. Kindly use it with caution.

    Hypoglycemia + Metformin

    During anti-diabetic medication, patients can experience hypoglycemia. Use with caution the patient who is having adrenal insufficiency, autonomic neuropathy, and receiving a beta-adrenergic blocking agent

    Vitamin B12 deficiency + Metformin

    Prolonged use of metformin can interfere with the absorption of vitamin b12 in the stomach. It may lead to anemia, tingling sensation, numbness in hands and feet, and ataxia. To avoid this effect kindly take the vitamin b12 from outside sources once a year

    Pancreatitis + Sitagliptin

    Therapy should be administered with caution in patients with pancreatitis because the use of this medicine associated with acute pancreatitis

    Renal dysfunction + Sitagliptin

    Therapy should be administered with caution in patients with renal impairment because the use of this medicine may cause acute renal failure


    Over Dose

    Take the medicine as directed by the doctor don’t overdose on the medicine. If you have taken an overdose on this medicine immediately meet the doctor and rush to the nearby hospital.


    Missed Dose

    Take the medicine as directed by the doctor. Do not skip the medicine, if you forgot to take the medicine or missed the dose. It is almost time for your next dose, skip the missed dose and go back to your regular schedule. Don’t take the extra dose take the regular dose immediately. Don’t use the two-dose at one time (Double Dose).


    Storage and Disposal

    • Stored at 30°C at room temperature.
    • Protect from light and heat.
    • Keep away from children and pets. Otherwise, it becomes toxic to them.
    • Disposed of properly in a suitable bag.


    Fast Tag

    • Sitazit M 50mg/500mg Tablet contains Sitagliptin 50mg and Metformin 500mg is a combination of two antidiabetic agents used to treat type 2 diabetes mellitus in adults.
    • This also helps to prevent serious complications of diabetes like kidney damage and blindness.
    • It produces its action by lowering the blood sugar level by increasing the amount of insulin that is released by the pancreas and liver.
    • Carry some sugary food or fruit juice with you if you have to experience hypoglycaemic symptoms such as cold sweets, cool pale skin, tremors, and anxiety
    • Kindly monitor your liver function while you are receiving this medicine
    • Inform your doctor if you have developed symptoms such as abdominal pain, loss of appetite, and jaundice