Tafero EM 25mg Tablet

Brand Name Tafero EM 25mg Tablet
Salt Composition Emtricitabine (200mg) + Tenofovir Alafenamide (25mg)
Strength 200mg + 25mg
Product Form Tablet
Storage Store at room temperature (10-30°C)
Category HIV
Country of Origin India
-20%
Tafero EM 25mg Tablet, Emtricitabine 200mg, Tenofovir Alafenamide 25mg, price, Uses, Side Effects - Drugcarts watermark
M.R.P : Rs.1757.50       Price : Rs.1406.00

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    Medical Description of Tafero EM 25mg Tablet

    Tafero-EM contains Emtricitabine 200mg and Tenofovir Alafenamide 25mg. Tafero-EM (Emtricitabine (200mg) + Tenofovir Alafenamide (25mg)) tablet is an antiviral medication. Tafero-EM tablet contains two nucleoside analogue reverse transcriptase inhibitor used in the treatment of HIV-1 infection. 


    Tafero EM 25mg Tablet Uses

    Tafero-EM (Emtricitabine (200mg) + Tenofovir Alafenamide (25mg)) tablet contains two nucleoside analogue reverse transcriptase inhibitor used in the treatment HIV-1 infection. Tafero-EM tablet can be safely used in children above 35Kgs and adults. Tafero-EM tablet is not recommended as pre-exposure prophylaxis for HIV-1 infection.


    Tafero EM 25mg Tablet Benefits

    Tafero-EM (Emtricitabine (200mg) + Tenofovir Alafenamide (25mg)) tablet controls HIV infection. Tafero-EM tablet helps to decrease the amount of HIV virus in your body thus your immunity works better by reducing your chance of getting HIV complications like co-infections and other cancers. Tafero-EM tablet is not a cure for HIV infection, it improves immunity that results in longevity of life; thus, precautions are necessary while sexual intercourse, surgery, etc. Tafero-EM tablet is safely used in children above 35Kgs and in adults.


    Tafero EM 25mg Tablet Indication

    Tafero-EM (Emtricitabine (200mg) + Tenofovir Alafenamide (25mg)) tablet is indicated in case of HIV infection that causes AIDS in humans. Tafero-EM tablet is indicated in children above 35kgs and adults. Patients are indicated to check for acute hepatitis B infection as the use of Tafero-EM tablet may flare up or worsen hepatitis condition.


    Mechanism of action of Tafero EM 25mg Tablet

    Tafero-EM (Emtricitabine (200mg) + Tenofovir Alafenamide (25mg)) tablet is a nucleotide reverse transcriptase inhibitor. Tenofovir Alafenamide present in Tafero-EM (Emtricitabine (200mg) + Tenofovir Alafenamide (25mg)) tablet enters hepatocytes where it is converted to tenofovir by hydrolysis. Hepatocyte tenofovir is then phosphorylated into tenofovir diphosphate that incorporates themselves into the DNA strand thus stops the replication of viral particles. Emtricitabine present in Tafero-EM tablet is an analogue of cytidine is phosphorylated to its active form. Emtricitabine 5 triphosphate inhibits the activity of HIV-1 reverse transcriptase and incorporates themselves into the DNA thus results in the termination of the replication process. Thus, the active HIV molecules become inactive and further reproduction and multiplication process is stopped.


    How Tafero EM 25mg Tablet works

    Tafero-EM (Emtricitabine (200mg) + Tenofovir Alafenamide (25mg)) tablet is a nucleotide reverse transcriptase inhibitor which has the active substance called Tenofovir Alafenamide and Emtricibine incorporates themselves into DNA strand and thus replication process of viral particle is terminated. Thus, the active HIV molecule becomes inactive and further reproduction and multiplication process is stopped.


    Tafero EM 25mg Tablet Contraindication

    • If you are HIV-1 positive and take Tafero-EM (Emtricitabine (200mg) + Tenofovir Alafenamide (25mg)) tablet as a pre exposure prophylactic
    • if you are allergic to Tafero-EM tablet and its contents
    • if you have liver disease like hepatitis B, C or liver cirrhosis
    • if you have kidney impairment
    • if you have osteoporosis
    • if <35Kgs of age
    • if you are breastfeeding
    • if you are pregnant


    Tafero EM 25mg Tablet Side Effects

    Very common side effects that occur in more than 1:10 patients: Headache

    Common side effects that occur 1:10 patients: Diarrhoea, vomiting, nausea, Dizziness, Stomach pain, arthralgia, fatigue

    Uncommon side effects that occur 1:100 patients: Swelling of the face, lips, tongue or throat, Hives, Increased level of ALT in the blood, exacerbation of hepatitis B

    Rare side effects that occur 1:1,000 patients: lactic acidosis, immune reconstitution syndrome, inflammatory hepatitis, renal impairment


    FAQs for Tafero EM 25mg Tablet

    Is Tafero-EM (Emtricitabine (200mg) + Tenofovir Alafenamide (25mg)) tablet safe during pregnancy?

    This medication is not recommended in pregnancy unless pros outweigh the cons. Consult your physician.

    Can Tafero-EM tablet be taken while breastfeeding?

    There is no specific study to detail this. But in general HIV virions can pass via breastfeeding thus it is suspected that antivirals can also pass via breastfeeding. Thus, consult your physician.

    Can Tafero-EM tablet be taken while alcohol consumption?

    The interaction is unknown but this medication causes dizziness. Thus, consult your physician.

    Can I take drive or operate heavy machineries while on Tafero-EM tablet?

    This medication causes dizziness and instability thus caution is used while driving or operating machineries.

    Can Tafero-EM tablet be taken as a prophylactic in HIV treatment?

    No, Tafero-EM tablet cannot be taken as a prophylactic if your HIV positive


    Precautions and general warning of Tafero EM 25mg Tablet

    Alcohol

    Tafero-EM (Emtricitabine (200mg) + Tenofovir Alafenamide (25mg)) tablet generally causes side effects thus it is advised not to be taken with alcohol. For further queries, consult your physician.

    Driving or operating machinery

    It is preferred to drive or operate heavy machinery with caution as Tafero-EM (Emtricitabine (200mg) + Tenofovir Alafenamide (25mg)) tablet causes side effects. For further queries, consult your physician.

    Pregnancy

    Tafero-EM (Emtricitabine (200mg) + Tenofovir Alafenamide (25mg)) tablet is cautiously used during pregnancy as it may cause some side effects on the fetus. Thus, consult your physician.

    Breast Feeding

    The use of Tafero-EM (Emtricitabine (200mg) + Tenofovir Alafenamide (25mg)) tablet during breastfeeding is not recommended as evidence shows less amount of the medication passes via breastfeeding to the baby that may cause an adverse effects in newborn.

    Kidney Problem

    Inform your physician if you have compromised kidney function as Tafero-EM (Emtricitabine (200mg) + Tenofovir Alafenamide (25mg)) tablet may cause renal disorders that results in end stage kidney failure

    Liver Disease

    Inform your physician if you have hepatitis B or C


    How to Take Tafero EM 25mg Tablet

    Tafero-EM (Emtricitabine (200mg) + Tenofovir Alafenamide (25mg)) tablet is taken orally with or without food.

    Tafero-EM tablet should be taken at a specific time every day.

    Don’t chew or break the tablet.

    Swallow Tafero-EM tablet as whole.

    After therapy has been initiated, do not take more or less of this medicine than prescribed or stop taking it without your physicians’ approval. Skipping or changing your dose without approval would increase the viral load making the infection more difficult to treat, or worsen side effects. For further queries consult your physician.


    Use of Tafero EM 25mg Tablet in Adult

    The recommended dosage of Tafero-EM (Emtricitabine (200mg) + Tenofovir Alafenamide (25mg)) tablet is single dose taken once per day orally with food.


    Use of Tafero EM 25mg Tablet in children

    The recommended dosage of Tafero-EM (Emtricitabine (200mg) + Tenofovir Alafenamide (25mg)) tablet in children is a single dose taken once per day with food

    The recommended age for the use of Tafero-EM tablet in children who weigh above 35 kgs.


    Use of Tafero EM 25mg Tablet in Elderly Patients

    Tafero-EM (Emtricitabine (200mg) + Tenofovir Alafenamide (25mg)) tablet has only been used in few patients 65 years or older. Dosage and usage are similar to adults. Discuss with your physician before usage.


    Other general warnings

    • Worsening renal impairment
    • Bone density disorders – decreases phosphate levels, causes osteoporosis
    • Lactic acidosis
    • Hepatomegaly with steatosis
    • Musculoskeletal problems - Osteonecrosis that causes joint stiffness and pain in larger joints like shoulder, hip, and knee
    • Accumulation or Redistribution of body fat
    • immune reconstitution syndrome.


    Talk to your doctor if

    If you have any allergy

    If you have a liver problem

    If you have any kidney diseases

    If you are diabetic

    If you have bone disorder

    If you are pregnant or breastfeeding


    General instructions

    In the case of HIV infection Tafero-EM (Emtricitabine (200mg) + Tenofovir Alafenamide (25mg)) tablet is taken orally at the prescribed dosage at a specific time regularly with food.

    Pre-screening for hepatitis B is recommended as this combination may worsen the infection


    Drug Interaction of Tafero EM 25mg Tablet

    Drug-Drug Interaction

    tipranavir/ritonavir

    carbamazepine

    oxcarbazepine

    phenobarbital

    phenytoin

    rifampin

    rifapentine

    St. John's wort (Hypericum perforatum)

    Drug-Food Interaction

    Tafero-EM (Emtricitabine (200mg) + Tenofovir Alafenamide (25mg)) tablet can be safely taken with any type of food, if doubts arise kindly refer to your physician. Tafero-EM tablet generally causes dizziness and instability thus it is advised not to be taken with alcohol.


    Over Dose

    Symptoms of overdose include dizziness, palpitations etc. Contact your doctor immediately.


    Missed Dose

    If you are treated with Tafero-EM (Emtricitabine (200mg) + Tenofovir Alafenamide (25mg)) tablet for HIV infection you can take the missed dose if you notice within 12 hours if you take them once a day. If it is more than 12 hours, then skip the dosage and take the next doses as usual.

     Don’t take a double dose for a forgotten dose.


    Storage and Disposal

    Store them at <30?C

    Keep the medication out of children’s reach

    Keep the medication away from pets

    Once expired dispose immediately


    Fast Tag

    Tafero-EM (Emtricitabine (200mg) + Tenofovir Alafenamide (25mg)) tablet is a nucleoside reverse transcriptase inhibitor

    It is used to control and treat HIV infection

    Do not use this medication while pregnant and lactation period.

    Don’t use this medication with liver disease and kidney disease.

    Don’t use this medication if you have previous hepatitis B infection

    Don’t use this medication as pre-prophylactic exposure if you are HIV positive

    This medication doesn’t stop the spread of HIV infection from person to person thus use caution and precaution while sexual contact, needle injury etc.