Tafero 25mg Tablet

Brand Name Tafero 25mg Tablet
Salt Composition Tenofovir Alafenamide (25mg)
Strength 25mg
Product Form Tablet
Storage Store at room temperature (10-30°C)
Category HIV
Country of Origin India
Manufacturer Hetero Healthcare Ltd
Manufacturer/Marketer AddressHetero Healthcare Ltd, S.no: 80-84, Melange towers, PatrikaNagar,Madhapur,Hyderabad. Telangana-500081.
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Tafero 25mg Tablet, Tenofovir Alafenamide 25mg, Price, Uses, Side Effects - Drugcarts watermark
M.R.P : Rs.1516.00       Price : Rs.1212.80

You Save : Rs.303.20    Inclusive of all taxes

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Availability : In Stock


    Medical Description of Tafero 25mg Tablet

    Tafero tablet contains Tenofovir Alafenamide 25mg. Tafero (Tenofovir Alafenamide (25mg)) tablet is an antiviral medication. Tafero tablet is a nucleoside analogue reverse transcriptase inhibitor used in the treatment of chronic Hepatitis B infection. Tafero tablet is safely used in patients with hepatic decompensation. Before use of Tafero tablet the patient needs to be checked for HIV infection. In case of HIV positive this medication will have to be used with other antivirals medicine. Tafero tablet can be safely used in children above 12 years of age and adults.


    Tafero 25mg Tablet Uses

    Tafero tablet is a nucleoside analogue reverse transcriptase inhibitor used in the treatment of chronic Hepatitis B infection and in combination with other antivirals to treat HIV-1 infection. Tafero tablet is used to treat adults and children above 12 years of age. If you have HIV your doctor will discuss which combination of medicines is best for you.


    Tafero 25mg Tablet Benefits

    Tafero (Tenofovir Alafenamide (25mg)) tablet is used with other anti-HIV medication to help control HIV infection. Tafero tablet helps to decrease the amount of HIV virus in your body thus your immunity works better by reducing your chance of getting HIV complications like co-infections and other cancers. Tafero tablet is not a cure for HIV infection, it improves immunity that results in longevity of life; thus, precautions are necessary while sexual intercourse, surgery, etc. Tafero tablet is also used in treatment of chronic hepatitis B. Tafero tablet is safely used in children above age 12 and in adults.


    Tafero 25mg Tablet Indication

    Tafero (Tenofovir Alafenamide (25mg)) tablet is indicated in the treatment of HIV infection that causes AIDS in humans. Tafero tablet is used with other antiviral medications to boost immunity of the affected hosts by reducing the viral load of the infected cells. Tafero tablet is also used in treatment of chronic hepatitis B. Tafero tablet is indicated in ages above 12 years and adults.


    Mechanism of action of Tafero 25mg Tablet

    Tafero (Tenofovir Alafenamide (25mg)) tablet is indicated in the trreatment of HIV infection that causes AIDS in humans. Tafero tablet is used with other antiviral medications to boost immunity of the affected hosts by reducing the viral load of the infected cells. Tafero tablet is also used in treatment of chronic hepatitis B. Tafero tablet is indicated in ages above 12 years and adults.

    Tafero (Tenofovir Alafenamide (25mg)) tablet is a nucleotide reverse transcriptase inhibitor that enters hepatocytes where it is converted to tenofovir by hydrolysis. Hepatocyte tenofovir is then phosphorylated into tenofovir diphosphate that incorporates themselves into the DNA strand thus stops the replication of viral particles.  Thus, the active HIV molecules and HBV virions become inactive and further reproduction and multiplication process is stopped.


    How Tafero 25mg Tablet works

    Tafero (Tenofovir Alafenamide (25mg)) tablet is a nucleotide reverse transcriptase inhibitor which has the active substance called tenofovir incorporates themselves into DNA strand and thus replication process of viral particle is terminated. Thus, the active HIV or HBV molecule becomes inactive and further reproduction and multiplication process is stopped.


    Tafero 25mg Tablet Contraindication

    • if you are allergic to Tafero (Tenofovir Alafenamide (25mg)) tablet
    • if you have liver disease like hepatitis C or liver cirrhosis
    • if you have osteoporosis
    • if you have pancreatitis
    • if you have kidney impairment
    • if <12 years of age
    • if you are breastfeeding
    • if you are pregnant


    Tafero 25mg Tablet Side Effects

    Very common side effects that occur in more than 1:10 patients: Headache

    Common side effects that occur 1:10 patients: Diarrhoea, vomiting, nausea, Dizziness, Stomach pain, arthralgia, Rash, Itchiness, Feeling bloated, fatigue

    Uncommon side effects that occur 1:100 patients: Swelling of the face, lips, tongue or throat, Hives, Increased level of ALT in the blood

    Rare side effects that occur 1:1,000 patients: lactic acidosis, immune reconstitution syndrome, inflammatory hepatitis, renal impairment, exacerbation of hepatitis B


    FAQs for Tafero 25mg Tablet

    Is Tafero (Tenofovir Alafenamide (25mg)) tablet safe during pregnancy?

    This medication is not recommended in pregnancy unless pros outweigh the cons. Consult your physician.

    Can Tafero tablet be taken while breastfeeding?

    There is no specific study to detail this. But in general HIV virions can pass via breastfeeding thus it is suspected that antivirals can also pass via breastfeeding. Thus, consult your physician.

    Can Tafero tablet be taken while alcohol consumption?

    The interaction is unknown but this medication causes dizziness. Thus, consult your physician.

    Can I take drive or operate heavy machineries while on Tafero tablet?

    This medication causes dizziness and instability thus caution is used while driving or operating machineries.

    Can Tafero tablet be taken as monotherapy in HIV treatment?

    No, Tafero must be taken with other antivirals.


    Precautions and general warning of Tafero 25mg Tablet

    Alcohol

    Tafero (Tenofovir Alafenamide (25mg)) tablet generally causes side effects thus it is advised not to be taken with alcohol. For further queries, consult your physician.

    Driving or operating machinery

    It is preferred to drive or operate heavy machinery with caution as Tafero (Tenofovir Alafenamide (25mg)) tablet causes side effects. For further queries, consult your physician.

    Pregnancy

    Tafero (Tenofovir Alafenamide (25mg)) tablet is cautiously used during pregnancy as it may cause some side effects on the fetus. Thus, consult your physician.

    Breast Feeding

    The use of Tafero (Tenofovir Alafenamide (25mg)) tablet during breastfeeding is not recommended as evidence shows less amount of the medication passes via breastfeeding to the baby that may cause adverse effects in newborn.

    Kidney Problem

    Consult your physician.

    Liver Disease

    Inform your physician if you have hepatitis B or C


    How to Take Tafero 25mg Tablet

    Tafero (Tenofovir Alafenamide (25mg)) tablet is taken orally with or without food.

    Tafero tablet should be taken at a specific time every day.

    Don’t chew or break the tablet.         

    Swallow Tafero tablet as a whole.

    In the case of HIV, Tafero tablet should be taken with other antivirals.

    After therapy has been initiated, do not take more or less of this drug than prescribed or stop taking it without your physicians’ approval. Skipping or changing your dose without approval would increase the viral load making the infection more difficult to treat, or worsen side effects. For further queries consult your physician.


    Use of Tafero 25mg Tablet in Adult

    The recommended dosage of Tafero (Tenofovir Alafenamide (25mg)) tablet in HBV infection is 25mg taken once per day orally with food

    The recommended dosage of Tafero tablet in HIV infection is 25mg taken once per day orally with other antivirals and food.


    Use of Tafero 25mg Tablet in children

    The recommended dosage of Tafero (Tenofovir Alafenamide (25mg)) tablet in children is 25mg taken once per day with food

    The recommended age for the use of Tafero tablet in children is more than 12 years of age


    Use of Tafero 25mg Tablet in Elderly Patients

    Tafero (Tenofovir Alafenamide (25mg)) tablet has only been used in few patients 65 years or older. Dosage and usage are similar to adults. Discuss with your physician before usage.


    Other general warnings

    • Worsening renal impairment
    • Bone density disorders
    • Heart diseases or disorders – MI
    • Musculoskeletal problems - Osteonecrosis that causes joint stiffness and pain in larger joints like shoulder, hip, and knee
    • Accumulation or Redistribution of body fat or immune reconstitution syndrome.


    Talk to your doctor if

    • If you have any allergy
    • If you have a liver problem
    • If you have any kidney diseases
    • If you are diabetic
    • If you are pregnant or breastfeeding


    General instructions

    In the case of HIV infection Tafero (Tenofovir Alafenamide (25mg)) tablet is taken with other antivirals orally at the prescribed dosage at specific time regularly with food.

    In the case of chronic HBV infection, Tafero tablet is taken at specific time regularly with food.


    Drug Interaction of Tafero 25mg Tablet

    Drug-Drug Interaction

    • Rifampicin,
    • Rifabutin,
    • Carbamazepine,
    • Phenobarbital or St. John's wort,
    • Phenytoin,
    • Midazolam,
    • Itraconazole,
    • Ketoconazole,
    • Rifampicin,
    • Rifapentine,
    • Atazanavir,
    • Darunavir,
    • Lopinavir

    Drug-Food Interaction

    Tafero (Tenofovir Alafenamide (25mg)) tablet can be safely taken with any type of food, if doubts arise kindly refer to your physician. Tafero tablet generally causes dizziness and instability thus it is advised not to be taken with alcohol.


    Over Dose

    Symptoms of overdose include dizziness, palpitations etc. Contact your doctor immediately.


    Missed Dose

    If you are treated with Tafero (Tenofovir Alafenamide (25mg)) tablet for chronic hepatitis B infection you can take the missed dosage if you notice within 18 hours if you take them once a day. If it is more than 18 hours, then skip the dosage and take the next doses as usual.

    If you are treated with Tafero tablet for HIV infection you can take the missed dose if you notice within 12 hours if you take them once a day. If it is more than 12 hours, then skip the dosage and take the next doses as usual.  Always take with other antivirals.

     Don’t take a double dose for a forgotten dose.


    Storage and Disposal

    Store them at <30?C

    Keep the medication out of children’s reach

    Keep the medication away from pets

    Once expired dispose immediately


    Fast Tag

    Tafero (Tenofovir Alafenamide (25mg)) tablet is a nucleoside reverse transcriptase inhibitor

    It is used to control and treat HIV infection with other antivirals

    It is used to treat chronic hepatitis B infection

    Do not use this medication while pregnant and lactation period.

    Don’t use this medication with liver disease and kidney disease.        

    This medication doesn’t stop the spread of HIV infection from person to person thus use caution and precaution while sexual contact, needle injury etc.