Taffic Tablet

Brand Name Taffic Tablet
Salt Composition Bictegravir (50mg) + Emtricitabine (200mg) + Tenofovir Alafenamide (25mg)
Strength 50mg + 200mg + 25mg
Product Form Tablet
Storage Store at room temperature (10-30°C)
Category HIV
Country of Origin India
Manufacturer Hetero Drugs Limited
Manufacturer/Marketer AddressHetero Drugs Limited,Hetero House, H. No. 8-3-166/7/1, Erragadda, Hyderabad, Andhra Pradesh, 500018 India
Taffic Tablet, Bictegravir 50mg, Tenofovir Alafenamide 25mg, Emtricitabine 200mg, price, Uses, Side Effects - Drugcarts watermark
M.R.P : Rs.4388.00       Price : Rs.3510.40

You Save : Rs.877.60    Inclusive of all taxes

- +

Availability : In Stock

    Medical Description of Taffic Tablet

    Taffic Tablet contains Bictegravir 50mg, Emtricitabine 200mg and Tenofovir Alafenamide 25mg. This combination is an antiviral medicine combination used in the treatment of Human Immunodeficiency Virus (HIV) – 1 infection. Bictegravir is an integrase strand transfer inhibitor. Emtricitabine and Tenofovir Alafenamide is a nucleoside reverse transcriptase inhibitor. It works by reducing the viral load of HIV in your body. This tablet combination improves your immune system and reduces the risk of conditions associated with HIV infection. 

    Taffic Tablet Uses

    Taffic tablet is used to treat adults and children above the weight class 25kg only who are infected by HIV-1.

    Taffic Tablet Benefits

    Taffic tablet is used to help control HIV infection & helps to decrease the amount of HIV in your body thus your immunity works better by reducing your chance of getting HIV complications like co-infections and other cancers. It is not a cure for HIV infection; it improves immunity that results in longevity of life. It is recommended for use in children from 25kgs and in adults.

    Taffic Tablet Indication

    Taffic tablet is indicated in the treatment of HIV-1 infection that causes AIDS in humans. These tablets boost the immunity of the affected hosts. Taffic tablet is indicated in adults and children above 25kgs.

    Mechanism of action of Taffic Tablet

    Taffic Tablet contains Bictegravir 50mg, Emtricitabine 200mg and Tenofovir Alafenamide 25mg. Bictegravir inhibits strand transfer activity of integrase in DNA thus blocks replication of HV-1. Emtricitabine is an analogue of cytidine that is phosphorylated to its active form Emtricibine 5 triphosphate that inhibits the activity of HIV-1 reverse transcriptase and incorporates themselves into the DNA thus results in termination of the replication process. Tenofovir Alafenamide enters hepatocytes where it is converted to tenofovir by hydrolysis. Hepatocyte tenofovir is then phosphorylated into tenofovir-diphosphate that incorporates themselves into the DNA strand thus stops the replication of viral particles. Thus, the active HIV molecules become inactive and further reproduction and multiplication process is stopped.

    How Taffic Tablet works

    Taffic tablet is an integrase inhibitor and nucleoside reverse transcriptase inhibitor. Bictegravir inhibits the transfer of integrase in DNA and Emtricitabine and tenofovir incorporates themselves into the DNA thus stops the replication of viral particles. Thereby preventing the formation of mature virus particles into infectious virions that spreads the infection.

    Taffic Tablet Contraindication

    Absolute contraindication:

    • if you are allergic to Taffic (Bictegravir (50mg) + Emtricitabine (200mg) + Tenofovir Alafenamide (25mg)) tablet and its contents
    • if you are pregnant
    • if you are diabetic

    Relative contraindication:

    • if you have a liver disorder like hepatitis B or C or Child-Pugh disease
    • if you have blood disorders
    • if you have renal diseases

    Taffic Tablet Side Effects

    Very common side effects that occur in more than 1:10 patients: Diarrhea 

    Common side effects that occur 1:10 patients: Nausea, Flatulence, Abdominal pain, Anemia, Allergic reaction, Impaired concentration, Lipodystrophy, Metabolic acidosis, Rash, Leukopenia, Thrombocytopenia, Weakness

    Uncommon side effects that occur 1:100 patients: lactic acidosis, hepatitis B flare up

    FAQs for Taffic Tablet


    Is Taffic (Bictegravir (50mg) + Emtricitabine (200mg) + Tenofovir Alafenamide (25mg)) tablet safe during pregnancy?

    No, Taffic tablet is not safe during pregnancy. Consult your physician.

    Can Taffic tablet be taken while breastfeeding?

    No, in general HIV virions can pass via breastfeeding thus it is suspected that antivirals can also pass via breastfeeding.

    Can Taffic tablets be taken while alcohol consumption?

    The interaction is unknown but this medication causes side effects. Thus, consult your physician.

    Can I take a drive or operate heavy machineries while on taffic?

    This medication causes side effects thus caution is used while driving or operating machineries.

    Can Taffic tablet be taken as a prophylactic to exposure?

    No, Taffic tablet cannot be taken as a prophylactic.

    Precautions and general warning of Taffic Tablet


    Taffic tablet generally causes side effects thus it is advised not to be taken with alcohol. For further queries, consult your physician.

    Driving or operating machinery

    It is preferred to drive or operate heavy machinery with caution as Taffic tablet causes side effects. For further queries, consult your physician.


    The use of Taffic tablet is not recommended during pregnancy.

    Breast Feeding

    The use of Taffic tablet during breastfeeding is not recommended as evidence shows less amount of the medication passes via breastfeeding to the baby that may cause adverse effect in newborn.

    Kidney Problem

    Renal filtration impairment and kidney stone formation – monitor function. For further queries, consult your physician.

    Liver Disease

    Liver disorders and diseases like hepatitis B or C, Child Pugh disease

    Monitor liver function before and during therapy, especially in patients with other

    How to Take Taffic Tablet

    Taffic tablet is taken orally with or without food at the regular time.

    Taffic tablet should not be crushed or chewed it must be swallowed.

    After therapy has been initiated, do not take more or less of this medicine than prescribed or stop taking it without your physicians’ approval. Skipping or changing tablet dose without approval may cause the amount of the virus to increase making the infection more difficult to treat, or worsen side effects.

    Use of Taffic Tablet in Adult

    If you are pregnant or breastfeeding inform your physician as they are not advisable.

    The recommended dosage for Taffic tablet is one tablet taken once per day

    These medicines must be taken with food on a regular time basis.

    Use of Taffic Tablet in children

    The recommended dosage of Taffic tablet is one tablet taken once per day

    Use of Taffic Tablet in Elderly Patients

    Taffic tablet has only been used in few patients 65 years or older. Dosage and usage are similar to adults. Discuss with your physician before usage.

    Other general warnings

    • New-onset diabetes mellitus or hyperglycemia – Monitor blood glucose and insulin levels. When needed add oral hypoglycemic and insulin
    • Blood disorders Hemophilia, hemolytic anemia
    • Skin reactions - It can be mild to severe like Stevens-Johnson Syndrome and toxic epidermal necrolysis.
    • Musculoskeletal problems - Osteonecrosis that causes joint stiffness and pain in larger joints like shoulder, hip, and knee
    • Accumulation or Redistribution of body fat or
    • immune reconstitution syndrome.
    • Any sign of infection – fever or lymph node enlargement
    • Lactose intolerance or galactose malabsorption

    Talk to your doctor if

    If you have any allergy

    If you have a liver problem

    If you have a kidney problem

    If you have hypertension or any heart problem

    If you are diabetic

    If you have a blood disorder

    If you are pregnant or breastfeeding

    General instructions

    Taffic tablet is an antiviral taken orally as a prescribed dosage at a specific time regularly with food.

    Drug Interaction of Taffic Tablet

    Drug-Drug Interaction

    Side effects are increased by aceclofenac, acyclovir, amikacin

    serum concentration is decreased by Acetazolamide, carbamazepine

    serum concentration is increased by Carvedilol, clomifene, acetaminophen

    Drug-Food Interaction

    Taffic tablet can be safely taken with food, if doubts arise kindly refer to your physician. These tablets generally causes side effects thus it is advised not to be taken with alcohol.

    Drug-Disease Interaction

    • Liver disorders – used with caution in severe liver diseases. Consult physician before use
    • Kidney disorders – used with caution in severe kidney diseases. Consult physician before use
    • Cardiac disorders – used with caution in prolonged QT syndrome. Consult physician before use
    • Respiratory disorders – used with caution in respiratory distress and asthma. Consult physician before use
    • Blood disorders – used with caution in hemolytic anemia and hemophilia. Consult physician before use

    Over Dose

    Contact your doctor, pharmacist or nurse immediately.

    Missed Dose

    In general, if you take once a day dosage, the missed single dose of Taffic tablet can be taken within the next 12 hrs, you can take it. If it is more than 12 hrs, skip the dose and take the next dose at the recommended time. Don’t take a double dose for a forgotten dose.

    Storage and Disposal

    Keep the medication out of children’s reach

    Keep the medication away from pets

    Once expired dispose immediately

    Store at 30°C

    Fast Tag

    Taffic tablet is a reverse transcriptase and integrase inhibitor.

    This tablet is used to control and treat HIV infection.

    Do not use this medication while pregnant or lactation period.

    Don’t use this medication with liver disease and kidney diseases.

    This medication doesn’t stop the spread of HIV infection from person to person thus use caution and precaution while sexual contact, needle injury, etc.