Tavin EM Tablet
Brand Name | Tavin EM Tablet |
Salt Composition |
Tenofovir disoproxil fumarate (300mg) + Emtricitabine (200mg) |
Strength | 300mg + 200mg |
Product Form | Tablet |
Pack | 30 Tablet(s) in Bottle |
Storage | Store below 30°C |
Category |
HIV |
SubCategory |
HIV |
Country of Origin | India |
Manufacturer |
Emcure Pharmaceuticals Ltd |
Manufacturer/Marketer Address | Emcure Pharmaceuticals Ltd./Add:255/2, Hinjawadi, Pune - 411057, India |
You Save : Rs.1,110.00 Inclusive of all taxes
- if you are a positive HIV case
- if you are allergic to Tavin EM (Tenofovir disoproxil fumarate (300mg) + Emtricitabine (200mg)) tablet and its combinate
- if you have liver disease like hepatitis B or C or hepatomegaly with steatosis
- if you have kidney impairment
- if <35 kgs of weight
- if you are breastfeeding
- Bone density loss
- Pancreatitis
- Lactic acidosis
- Hepatic decompensation
- Musculoskeletal problems - Osteonecrosis that causes joint stiffness and pain in larger joints like shoulder, hip, and knee
- Accumulation or Redistribution of body fat
- immune reconstitution syndrome.
Medical Description of Tavin EM Tablet
Tavin EM tablet contains Tenofovir disoproxil fumarate 300mg and Emtricitabine 200mg. Tavin EM (Tenofovir disoproxil fumarate (300mg) + Emtricitabine (200mg)) tablet is an antiviral medicine used in the treatment of Human Immunodeficiency Virus (HIV)-1 infection. Tavin EM tablet is a nucleotide reverse transcriptase inhibitor. Tavin EM tablet acts on HIV reverse transcriptase enzyme thus interfere with their reproduction cycle.
Tavin EM Tablet Uses
Tavin EM (Tenofovir disoproxil fumarate (300mg) + Emtricitabine (200mg)) tablet is used to treat adults and adolescence above 18 years of age who are infected by HIV. Tavin EM tablet is used in caution with liver and renal impairment patients.
Tavin EM Tablet Benefits
Tavin EM (Tenofovir disoproxil fumarate 300 mg + Emtricitabine 200 mg) is used with other anti-HIV medication to help control HIV infection. Tavin EM tablet helps to decrease the amount of HIV virus in your body thus your immunity works better by reducing your chance of getting HIV complications like co-infections and other cancers. Tavin EM tablet is not a cure for HIV infection, it improves immunity that results in longevity of life; thus, precautions are necessary while sexual intercourse, surgery etc. Tavin EM tablet is safely used in adolescence above 35 kgs of weight. Tavin EM tablet is used as a pre prophylactic to exposure in a previously negative HIV test.
Tavin EM Tablet Indication
Tavin EM (Tenofovir disoproxil fumarate (300mg) + Emtricitabine (200mg)) tablet is indicated in the treatment of HIV infection that causes AIDS in humans. Tavin EM tablet is used with other antiviral medications to boost immunity of the affected hosts by reducing the viral load of the infected cells. Tavin EM tablet is safely used in adolescence above 35 kgs of weight. Tavin EM tablet is used as a pre prophylactic to exposure in a previously negative HIV test.
Mechanism of action of Tavin EM Tablet
Tavin EM (Tenofovir disoproxil fumarate (300mg) + Emtricitabine (200mg)) tablet is a nucleotide reverse transcriptase inhibitor. Tenofovir disoproxil fumarate present in Tavin EM tablet is an analogue of adenosine 5-monophosphate which is converted to tenofovir after hydrolysis after which tenofovir inhibits HIV-1 reverse transcriptase and HBV reverse transcriptase. Tenofovir competes with AMP as a substrate and competes to incorporate themselves into the DNA strand thus stops the replication of viral particles. Emtricitabine present in Tavin EM tablet is an analogue of cytidine is phosphorylated to its active form. Emtricitabine 5 triphosphate inhibits the activity of HIV-1 reverse transcriptase and incorporates themselves into the DNA thus results in the termination of replication process. Thus, the active HIV molecule becomes inactive and further reproduction and multiplication process is stopped by the use of Tavin EM tablet.
How Tavin EM Tablet works
Tavin EM (Tenofovir disoproxil fumarate (300mg) + Emtricitabine (200mg)) tablet competes with AMP and cytidine respectively and incorporates themselves into DNA strand and thus replication process of viral particle is terminated. Thus, the active HIV molecule becomes inactive and further reproduction and multiplication process is stopped.
Tavin EM Tablet Contraindication
Tavin EM Tablet Side Effects
Common side effects that occur 1:10 patients: diarrhea, nausea, fatigue, headache, dizziness, depression, insomnia, abnormal dreams, and rash
Rare side effects that occur 1:1,000 patients: hepatomegaly, worsening hepatitis B infection, decreased bone density,
Very rare side effects that occur 1:10,000 patients: lactic acidosis, immune reconstitution syndrome, Interstitial Nephritis, peripheral neuropathy, Fanconi syndrome, renal tubular necrosis, inflammatory hepatitis, angioedema
FAQs for Tavin EM Tablet
Is Tavin EM (Tenofovir disoproxil fumarate (300mg) + Emtricitabine (200mg)) tablet safe during pregnancy?
This medication is not recommended in pregnancy unless pros outweigh the cons. Consult your physician.
Can Tavin EM tablet be taken while breastfeeding?
There is no specific study to detail this. But in general HIV virions can pass via breastfeeding thus it is suspected that antivirals can also pass via breastfeeding. Thus, consult your physician.
Can Tavin EM tablet be taken while alcohol consumption?
The interaction is unknown but this medication causes dizziness. Thus, consult your physician.
Can I take drive or operate heavy machineries while on Tavin EM tablet?
This medication causes dizziness and instability thus caution is used while driving or operating machineries.
Can Tavin EM tablet be taken as a prophylactic?
Yes, only if you are tested negative immediately after exposure. Please consult a physician before use.
Precautions and general warning of Tavin EM Tablet
Alcohol
Tavin EM (Tenofovir disoproxil fumarate (300mg) + Emtricitabine (200mg)) tablet generally causes side effects thus it is advised not to be taken with alcohol. For further queries, consult your physician.
Driving or operating machinery
It is preferred to drive or operate heavy machinery with caution as Tavin EM (Tenofovir disoproxil fumarate (300mg) + Emtricitabine (200mg)) tablet causes side effects. For further queries, consult your physician.
Pregnancy
Tavin EM (Tenofovir disoproxil fumarate (300mg) + Emtricitabine (200mg)) tablet is cautiously used during pregnancy as it may cause some side effects on the fetus. Thus, consult your physician.
Breast Feeding
The use of Tavin EM (Tenofovir disoproxil fumarate (300mg) + Emtricitabine (200mg)) tablet during breastfeeding is not recommended as evidence shows less amount of the medication passes via breastfeeding to the baby that may cause adverse effect in newborn.
Kidney Problem
Inform your physician if you have compromised kidney function as Tavin EM (Tenofovir disoproxil fumarate (300mg) + Emtricitabine (200mg)) tablet may cause renal disorders that results in end-stage kidney failure
Liver Disease
Inform your physician if you have hepatitis B or C
Hepatomegaly with steatosis
How to Take Tavin EM Tablet
Tavin EM (Tenofovir disoproxil fumarate (300mg) + Emtricitabine (200mg)) tablet is taken orally with or without food.
Tavin EM tablet should be taken at a specific time every day.
Don’t chew or break the tablet.
Swallow Tavin EM tablet as whole.
After therapy has been initiated, do not take more or less of this drug than prescribed or stop taking it without your physicians’ approval. Skipping or changing your dose without approval would increase the viral load making the infection more difficult to treat, or worsen side effects. For further queries consult your physician.
Use of Tavin EM Tablet in Adult
The recommended dosage is a single dose of Tavin EM (Tenofovir disoproxil fumarate (300mg) + Emtricitabine (200mg)) tablet taken once per day with or without food
Use of Tavin EM Tablet in children
The recommended dosage of Tavin EM (Tenofovir disoproxil fumarate (300mg) + Emtricitabine (200mg)) tablet in single dose taken once per day orally with or without food
Use of Tavin EM Tablet in Elderly Patients
Tavin EM (Tenofovir disoproxil fumarate (300mg) + Emtricitabine (200mg)) tablet has only been used in few patients 65 years or older. Dosage and usage are similar to adults. Discuss with your physician before usage.
Other general warnings
Talk to your doctor if
If you have any allergy
If you have a liver problem
If you have any kidney diseases
If you are pregnant or breastfeeding
General instructions
Tavin EM (Tenofovir disoproxil fumarate (300mg) + Emtricitabine (200mg)) tablet is taken at specific time regularly with food. If Tavin EM tablet is taken without food the efficiency of medicine is reduced significantly, thus it is ill advised.
Drug Interaction of Tavin EM Tablet
Drug-Drug Interaction
Atazanavir/Acyclovir/Amikacin/Amphotericin B
Carbamazepine/Clarithromycin
Didanosine/Deferoxime/
Probenecid/Phenobarbital/Phenytoin
Ibuprofen
Ketorolac/Ketoconazole
Mefenamic acid/ Methadone
Naproxen
Fluconazole
Rifampin
Drug-Food Interaction
Tavin EM (Tenofovir disoproxil fumarate (300mg) + Emtricitabine (200mg)) tablet can be safely taken with any type of food, if doubts arise kindly refer to your physician. Tavin EM tablet generally causes known side-effects thus it is advised not to be taken with alcohol.
Over Dose
Symptoms of overdose include dizziness, palpitations etc. Contact your doctor immediately.
Missed Dose
You can take the missed dosage if you notice within 12 hours if you take them once a day. If it is more than 12 hours, then skip the dosage and take the next doses as usual. Don’t take a double dose for a forgotten dose.
Storage and Disposal
Store them at <30°C
Keep the medication out of children’s reach
Keep the medication away from pets
Once expired dispose immediately
Fast Tag
Tavin EM (Tenofovir disoproxil fumarate (300mg) + Emtricitabine (200mg)) tablet is a nucleotide reverse transcriptase inhibitor
It is used to control and treat HIV infection
Do not use this medication while pregnant and lactation period.
Don’t use this medication with liver disease and kidney disease.
Do not use this medication as a prophylactic, consult a physician before use
This medication doesn’t stop the spread of HIV infection from person to person thus use caution and precaution while sexual contact, needle injury etc.