Tenof EM Tablet

Brand Name Tenof EM Tablet
Salt Composition Tenofovir disoproxil fumarate (300mg) + Emtricitabine (200mg)
Strength 300mg + 200mg
Product Form Tablet
Storage Store at room temperature (10-30°C)
Category HIV
Country of Origin India
Manufacturer Hetero Healthcare Ltd
Manufacturer/Marketer AddressHetero Healthcare Ltd, S.no: 80-84, Melange towers, PatrikaNagar,Madhapur,Hyderabad. Telangana-500081.
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Tenof EM Tablet, Emtricitabine 200mg, Tenofovir Disoproxil fumarate 300mg, price, Uses, Side Effects - Drugcarts watermark
M.R.P : Rs.1540.00       Price : Rs.1309.00

You Save : Rs.231.00    Inclusive of all taxes

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Availability : In Stock


    Medical Description of Tenof EM Tablet

    Tenof EM tablet contains Tenofovir disoproxil fumarate 300mg and Emtricitabine 200mg. Tenof EM (Tenofovir disoproxil fumarate (300mg) + Emtricitabine (200mg)) tablet is an antiviral medicine used in the treatment of Human Immunodeficiency Virus (HIV)-1 infection. Tenof EM tablet is a nucleotide reverse transcriptase inhibitor. Tenof EM tablet acts on HIV reverse transcriptase enzyme thus interfere with their reproduction cycle.


    Tenof EM Tablet Uses

    Tenof EM (Tenofovir disoproxil fumarate (300mg) + Emtricitabine (200mg)) tablet is used to treat adults and adolescence above 18 years of age who are infected by HIV. Tenof EM tablet is used in caution with liver and renal impairment patients.


    Tenof EM Tablet Benefits

    Tenof EM (Tenofovir disoproxil fumarate 300 mg + Emtricitabine 200 mg) is used with other anti-HIV medication to help control HIV infection. Tenof EM tablet helps to decrease the amount of HIV virus in your body thus your immunity works better by reducing your chance of getting HIV complications like co-infections and other cancers. Tenof EM tablet is not a cure for HIV infection, it improves immunity that results in longevity of life; thus, precautions are necessary while sexual intercourse, surgery etc. Tenof EM tablet is safely used in adolescence above 35 kgs of weight. Tenof EM tablet is used as a pre prophylactic to exposure in a previously negative HIV test.


    Tenof EM Tablet Indication

    Tenof EM (Tenofovir disoproxil fumarate (300mg) + Emtricitabine (200mg)) tablet is indicated in the treatment of HIV infection that causes AIDS in humans. Tenof EM tablet is used with other antiviral medications to boost immunity of the affected hosts by reducing the viral load of the infected cells. Tenof EM tablet is safely used in adolescence above 35 kgs of weight. Tenof EM tablet is used as a pre prophylactic to exposure in a previously negative HIV test.


    Mechanism of action of Tenof EM Tablet

    Tenof EM (Tenofovir disoproxil fumarate (300mg) + Emtricitabine (200mg)) tablet is a nucleotide reverse transcriptase inhibitor. Tenofovir disoproxil fumarate present in Tenof EM tablet is an analogue of adenosine 5-monophosphate which is converted to tenofovir after hydrolysis after which tenofovir inhibits HIV-1 reverse transcriptase and HBV reverse transcriptase. Tenofovir competes with AMP as a substrate and competes to incorporate themselves into the DNA strand thus stops the replication of viral particles. Emtricitabine present in Tenof EM tablet is an analogue of cytidine is phosphorylated to its active form. Emtricitabine 5 triphosphate inhibits the activity of HIV-1 reverse transcriptase and incorporates themselves into the DNA thus results in the termination of replication process. Thus, the active HIV molecule becomes inactive and further reproduction and multiplication process is stopped by the use of Tenof EM tablet.


    How Tenof EM Tablet works

    Tenof EM (Tenofovir disoproxil fumarate (300mg) + Emtricitabine (200mg)) tablet competes with AMP and cytidine respectively and incorporates themselves into DNA strand and thus replication process of viral particle is terminated. Thus, the active HIV molecule becomes inactive and further reproduction and multiplication process is stopped.


    Tenof EM Tablet Contraindication

    • if you are a positive HIV case
    • if you are allergic to Tenof EM (Tenofovir disoproxil fumarate (300mg) + Emtricitabine (200mg)) tablet and its combinate
    • if you have liver disease like hepatitis B or C or hepatomegaly with steatosis
    • if you have kidney impairment
    • if <35 kgs of weight
    • if you are breastfeeding


    Tenof EM Tablet Side Effects

    Common side effects that occur 1:10 patients: diarrhea, nausea, fatigue, headache, dizziness, depression, insomnia, abnormal dreams, and rash

    Rare side effects that occur 1:1,000 patients: hepatomegaly, worsening hepatitis B infection, decreased bone density,

    Very rare side effects that occur 1:10,000 patients: lactic acidosis, immune reconstitution syndrome, Interstitial Nephritis, peripheral neuropathy, Fanconi syndrome, renal tubular necrosis, inflammatory hepatitis, angioedema


    FAQs for Tenof EM Tablet

    Is Tenof EM (Tenofovir disoproxil fumarate (300mg) + Emtricitabine (200mg)) tablet safe during pregnancy?

    This medication is not recommended in pregnancy unless pros outweigh the cons. Consult your physician.

    Can Tenof EM tablet be taken while breast feeding?

    There is no specific study to detail this. But in general HIV virions can pass via breastfeeding thus it is suspected that antivirals can also pass via breastfeeding. Thus, consult your physician.

    Can Tenof EM tablet be taken while alcohol consumption?

    The interaction is unknown but this medication causes dizziness. Thus, consult your physician.

    Can I take drive or operate heavy machineries while on Tenof EM tablet?

    This medication causes dizziness and instability thus caution is used while driving or operating machineries.

    Can Tenof EM tablet be taken as a prophylactic?

    Yes, only if you are tested negative immediately after exposure. Please consult a physician before use.


    Precautions and general warning of Tenof EM Tablet

    Alcohol

    Tenof EM (Tenofovir disoproxil fumarate (300mg) + Emtricitabine (200mg)) tablet generally causes side effects thus it is advised not to be taken with alcohol. For further queries, consult your physician.

    Driving or operating machinery

    It is preferred to drive or operate heavy machinery with caution as Tenof EM (Tenofovir disoproxil fumarate (300mg) + Emtricitabine (200mg)) tablet causes side effects. For further queries, consult your physician.

    Pregnancy

    Tenof EM (Tenofovir disoproxil fumarate (300mg) + Emtricitabine (200mg)) tablet is cautiously used during pregnancy as it may cause some side effects on the fetus. Thus, consult your physician.

    Breast Feeding

    The use of Tenof EM (Tenofovir disoproxil fumarate (300mg) + Emtricitabine (200mg)) tablet during breastfeeding is not recommended as evidence shows less amount of the medication passes via breastfeeding to the baby that may cause adverse effect in newborn.

    Kidney Problem

    Inform your physician if you have compromised kidney function as Tenof EM (Tenofovir disoproxil fumarate (300mg) + Emtricitabine (200mg)) tablet may cause renal disorders that results in end-stage kidney failure

    Liver Disease

    Inform your physician if you have hepatitis B or C

    Hepatomegaly with steatosis


    How to Take Tenof EM Tablet

    Tenof EM (Tenofovir disoproxil fumarate (300mg) + Emtricitabine (200mg)) tablet is taken orally with or without food.

    Tenof EM tablet should be taken at a specific time every day.

    Don’t chew or break the tablet.

    Swallow Tenof EM tablet as whole.

    After therapy has been initiated, do not take more or less of this drug than prescribed or stop taking it without your physicians’ approval. Skipping or changing your dose without approval would increase the viral load making the infection more difficult to treat, or worsen side effects. For further queries consult your physician.


    Use of Tenof EM Tablet in Adult

    The recommended dosage is a single dose of Tenof EM (Tenofovir disoproxil fumarate (300mg) + Emtricitabine (200mg)) tablet taken once per day with or without food


    Use of Tenof EM Tablet in children

    The recommended dosage of Tenof EM (Tenofovir disoproxil fumarate (300mg) + Emtricitabine (200mg)) tablet in single dose taken once per day orally with or without food


    Use of Tenof EM Tablet in Elderly Patients

    Tenof EM (Tenofovir disoproxil fumarate (300mg) + Emtricitabine (200mg)) tablet has only been used in few patients 65 years or older. Dosage and usage are similar to adults. Discuss with your physician before usage.


    Other general warnings

    • Bone density loss
    • Pancreatitis
    • Lactic acidosis
    • Hepatic decompensation
    • Musculoskeletal problems - Osteonecrosis that causes joint stiffness and pain in larger joints like shoulder, hip, and knee
    • Accumulation or Redistribution of body fat
    • immune reconstitution syndrome.


    Talk to your doctor if

    If you have any allergy

    If you have a liver problem

    If you have any kidney diseases

    If you are pregnant or breastfeeding


    General instructions

    Tenof EM (Tenofovir disoproxil fumarate (300mg) + Emtricitabine (200mg)) tablet is taken at specific time regularly with food. If Tenof EM tablet is taken without food the efficiency of medicine is reduced significantly, thus it is ill advised.


    Drug Interaction of Tenof EM Tablet

    Drug-Drug Interaction

    Atazanavir/Acyclovir/Amikacin/Amphotericin B

    Carbamazepine/Clarithromycin

    Didanosine/Deferoxime/

    Probenecid/Phenobarbital/Phenytoin

    Ibuprofen

    Ketorolac/Ketoconazole

    Mefenamic acid/ Methadone

    Naproxen

    Fluconazole

    Rifampin

    Drug-Food Interaction

    Tenof EM (Tenofovir disoproxil fumarate (300mg) + Emtricitabine (200mg)) tablet can be safely taken with any type of food, if doubts arise kindly refer to your physician. Tenof EM tablet generally causes known side-effects thus it is advised not to be taken with alcohol.


    Over Dose

    Symptoms of overdose include dizziness, palpitations etc. Contact your doctor immediately.


    Missed Dose

    You can take the missed dosage if you notice within 12 hours if you take them once a day. If it is more than 12 hours, then skip the dosage and take the next doses as usual. Don’t take a double dose for a forgotten dose.


    Storage and Disposal

    Store them at <30°C

    Keep the medication out of children’s reach

    Keep the medication away from pets

    Once expired dispose immediately


    Fast Tag

    Tenof EM (Tenofovir disoproxil fumarate (300mg) + Emtricitabine (200mg)) tablet is a nucleotide reverse transcriptase inhibitor

    It is used to control and treat HIV infection

    Do not use this medication while pregnant and lactation period.

    Don’t use this medication with liver disease and kidney disease.

    Do not use this medication as a prophylactic, consult a physician before use

    This medication doesn’t stop the spread of HIV infection from person to person thus use caution and precaution while sexual contact, needle injury etc.