Thiozit A 100mg/4mg Tablet

Thiozit A 100mg/4mg Tablet contains Aceclofenac 100mg and Thiocolchicoside (4mg) is used to treat pain that occurs due to muscle spasms associated with low back pain, neck pain, sprains, dorsal pain, neck muscle contraction, and degenerative vertebral disorders. The combination of this medicine produces its action by inhibiting the release of chemical substances which cause pain by relieving the pain which is associated with muscle spasms.

It is used in the treatment of the pain due to muscle spasms associated with low back pain, neck pain, sprains, dorsal pain, neck muscle contraction, and degenerative vertebral disorders

Muscle spasm

It is an involuntary contraction of one or more muscles. Mostly these muscle cramps develop in your leg muscles in the calf. It occurs when the overuse of a muscle, dehydration, muscle strain, and nerve compression.

The Thiozit A 100mg/4mg Tablet is prescribed for the following indications as pain due to muscle spasms associated with low back pain, neck pain, sprains, dorsal pain, neck muscle contraction, and degenerative vertebral disorders

Thiozit A 100mg/4mg Tablet contains Aceclofenac 100mg and Thiocolchicoside (4mg). Aceclofenac is an analgesic and anti-inflammatory medication. It produces its action by inhibiting the cyclooxygenase (COX-1) and (COX-2). Thus it inhibits the synthesis of prostaglandins which is responsible for pain and inflammation. It also inhibits the aggregation and activation of neutrophil and chemotaxis, decreases the proinflammatory cytokine level, and alter the activity of lymphocyte.

Thiocolchicoside is a muscle relaxant that produces its action by working in the centre of your brain and spinal cord and relieving stiffness of your muscle and it also helps to improve the pain and muscle movement.

Thiozit A 100mg/4mg Tablet contains Aceclofenac 100mg and Thiocolchicoside (4mg). Aceclofenac is an analgesic and anti-inflammatory medication. It produces its action by inhibiting the cyclooxygenase (COX-1) and (COX-2). Thus it inhibits the synthesis of prostaglandins which is responsible for pain and inflammation. It also inhibits the aggregation and activation of neutrophil and chemotaxis, decreases the proinflammatory cytokine level, and alter the activity of lymphocyte.

Thiocolchicoside is a muscle relaxant that produces its action by working in the centre of your brain and spinal cord and relieving stiffness of your muscle and it also helps to improve the pain and muscle movement.

• Do not take this medicine if you are allergic to Aceclofenac and Thiocolchicoside

• Edema
• Headache
• Dizziness
• Abdominal pain
• Constipation
• Diarrhea
• Flatulence
• Heartburn
• GI ulcers
• Loss of appetite
• Sleepiness

• Does the Thiozit A 100mg/4mg Tablet make you drowsy?

Yes, the use of this capsule makes you feel drowsy, fatigue and drowsiness but it is considered a common effect.

• Can the Thiozit A 100mg/4mg Tablet damage your kidneys?

Long-term use of this medicine may cause renal damage such as protein or blood in urine and painful urination. Kindly monitor the patient's kidney function.

• Is the Thiozit A 100mg/4mg Tablet safe?

Yes, it is safe to use this medicine if you have taken the medicine as per the dose and duration advised by your doctor. Kindly consult with your doctor if you have experienced any side effects.

Alcohol

It is considered unsafe to consume alcohol while taking this medication. Kindly consult with your doctor

Driving or operating machinery

It is considered unsafe to drive while you are receiving this medicine it may affect your ability to drive. Kindly consult with your doctor.

Pregnancy

It is considered unsafe during pregnancy because it may produce harmful effects on the fetus. Kindly consult with your doctor.

Breast Feeding

Limited information is available regarding the use of this medicine in patients during breastfeeding. Kindly consult with your doctor.

Kidney Problem

This medicine should be used with caution in patients with renal impairment. The use of this medicine required dose modification. Kindly consult with your doctor.

Liver Disease

This medicine should be used with caution in patients with severe liver impairment. The use of this medicine required dose modification. Kindly consult with your doctor.

The capsule is taken orally with food. You should not chew, cut or crush the capsule. Dissolve it in a glass of water. Take this medicine as per the dose and duration advised by your doctor. Follow the direction mentioned within the label if you probably did not understand the appliance kindly ask your doctor or pharmacist to elucidate in detail. Do not withdraw the medicine when you feel better kindly complete the course of treatment to avoid reoccurrence.

It is considered to be safe to use this medicine in an adult patient if the medicine is prescribed by a doctor. Kindly consult with your doctor.

Thiozit A 100mg/4mg Tablet is considered unsafe in children who are below 12 years old. Kindly consult with your doctor.

Thiozit A 100mg/4mg Tablet should be used with caution in patients with an elderly age group, which leads to developing further medical problems, leads to worsening the patient's health conditions. Kindly consult with your doctor. Dose modification or replacement is required based on the medical conditions of the patient.

• Nonsteroidal anti-inflammatory drugs may increase the risk of developing cardiovascular thrombotic events, myocardial infarction, and stroke
• The use of this medicine also increases the risk of developing serious GI adverse events including bleeding, ulceration, and gastric perforation
• Therapy should be administered with caution in patients with bronchospasm, cardiac diseases, hepatic porphyria, hypertension, fluid retention, severe renal impairment, smoking, and systemic lupus erythematosus
• The use of this medicine decrease platelet aggregation and may prolong the bleeding time
• Therapy should be administered with caution in patients with blood dyscrasias, and bone marrow depression
• The use of this medicine may increase the risk of hyperkalemia and aseptic meningitis
• The use of this medicine may cause sedation and visual hallucinations and Hepatotoxicity
• Therapy should be administered with caution in patients with renal and hepatic impairment

• You have a history of gastrointestinal disease
• You are not responding to the treatment
• You have experienced any allergic reactions like rashes and itching
• You are suffering from anemia
• You have watery diarrhea, stomach pain, and fever

Aceclofenac 100mg and Thiocolchicoside (4mg) are used to treat pain that occurs due to muscle spasms. The combination of this medicine produces its action by inhibiting the release of chemical substances which cause pain by relieving the pain which is associated with muscle spasms.

Drug-Drug Interaction

Apixaban  

The use of this drug is contraindicated because the combination of this drug increases the effect of anticoagulation

Captopril  

Use alternative drug because the use of the non-steroidal anti-inflammatory drug may decrease the effectiveness of the antihypertensive drug and the combination of these drugs also decrease the renal functions

Aliskiren 

Therapy should be administered with caution because the use of aceclofenac will decrease the effect of aliskiren on other

Drug-Food Interaction

Alcohol

The use of alcohol should be avoided in patients who are taking NSAIDs because it may increase the risk of bleeding in the stomach which includes tarry, bloody stools, or coughing up blood while vomiting.  Do not withdraw the medication without consulting with the doctor

Drug-Disease Interaction

Asthma  

Therapy should be administered with caution in patients who are having asthma because the use of the non-steroidal anti-inflammatory drug (NSAIDs) in asthma patients may cause nasal polyposis, pansinusitis, eosinophilia, and rhinitis. Before initiating the therapy ask the patients whether they are allergic to salicylate salts.

Heart failure  

Therapy should be administered with caution in patients with heart failure because the use of NSAIDs may cause fluid retention and edema

Hepatotoxicity  

Therapy should be administered with caution in a patient with liver diseases because the use of NSAIDs may increase the serum transaminases, LDH, and alkaline phosphatase. And in rare cases, it may cause hepatotoxicity including liver cirrhosis, jaundice, and hepatic failure

Hypertension  

Therapy should be administered with caution in patients with hypertension because the use of NSAIDs may increase blood pressure and cardiovascular events. During this course of treatment monitor the patient blood pressure

Renal toxicities  

Therapy should be administered with caution in a patient with renal diseases because the use of NSAIDs may increase the serum creatinine, BUN, tubular necrosis, glomerulus, renal papillary necrosis, nephrotic syndrome, and cause renal failure.

Take the medicine as directed by the doctor don’t overdose on the medicine. If you have taken an overdose on this medicine immediately meet the doctor and rush to the nearby hospital.

Take the medicine as directed by the doctor. Do not skip the medicine, if you forgot to take the medicine or missed the dose. It is almost time for your next dose, skip the missed dose and go back to your regular schedule. Don’t take the extra dose take the regular dose immediately. Don’t use the two-dose at one time (Double Dose).

• Stored at 10-30°C room temperature.
• Protect from light and heat.
• Keep away from children and pets. Otherwise, it becomes toxic to them.
• Disposed of properly in a suitable bag

• Thiozit A 100mg/4mg Tablet contains Aceclofenac 100mg and Thiocolchicoside (4mg) is used to treat pain that occurs due to muscle spasms associated with low back pain, neck pain, sprains, dorsal pain, neck muscle contraction, and degenerative vertebral disorders
• It produces its action by inhibiting the release of chemical substances which cause pain and it also helps by relieving the pain which is associated with muscle spasms.
• Kindly inform your doctor if you have a history of heart disease or stroke
• The tablet is taken orally by mouth with food
• Monitor the patient's kidney functions, liver function, and levels of blood components
• Avoid consuming alcohol because it may cause excessive drowsiness and stomach problem