Tigebax 50mg Injection

Brand Name Tigebax 50mg Injection
Salt Composition

Tigecycline (50mg)

Strength 50mg
Product Form Injection
Pack 1 Injection in 1 Vial
Storage Store below 25°C
Category

Antibiotic

SubCategory

Anti-Biotic

Country of Origin India
Manufacturer

Glenmark Pharmaceuticals Ltd

Manufacturer/Marketer Address Glenmark Pharmaceuticals Limited, B/2, Mahalaxmi Chambers, 22, Bhulabhai Desai Road, Mumbai – 400 026.
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M.R.P : Rs.5146.50       Price : Rs.4631.85

You Save : Rs.514.65    Inclusive of all taxes

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1 Injection in 1 Vial

Availability : In Stock

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    Medical Description of Tigebax 50mg Injection

    Tigebax 50mg injection contains Tigecycline 50mg used to treat severe bacterial infections such as Intraabdominal infections, Skin and skin structure infections, and Pneumonia. Tigecycline is an antibiotic that kills the bacteria and also helps to improve the symptoms and treat the infection. Mainly this bacterial infection targets the skin, intra-abdominal infection, and community-acquired pneumonia. This medicine is not used for common flu and cold symptoms that occur due to viral infections. This medicine is commonly prescribed for cough and colds caused by bacterial infections.


    Tigebax 50mg Injection Uses

    It is used in the treatment of the following conditions as bacterial infections such as Intraabdominal infections, Skin and skin structure infections, and Pneumonia


    Tigebax 50mg Injection Benefits

    Bacterial infections

    Bacterial infection occurs when bacteria enter your body and start multiplying which may cause tissue damage and make you sick. Mostly it is caused by Staphylococcus and Streptococcus organisms. The bacterial diseases are cholera, bacterial meningitis, tetanus, gonorrhea, pneumonia, and syphilis. Symptoms include fever, chills, and sweats, inflamed lymph nodes, headache, diarrhea, abdominal pain

    Intraabdominal infections

    Infection and inflammation to the internal organs of the abdomen caused by E.coli, streptococcus, and enterococcus bacteria called Intraabdominal infection include peritonitis, intra- abdominal abscess, appendicitis. This medicine is used to treat this bacterial infection.

    Skin and skin structure infections

    Infections such as cellulitis wound infection and cutaneous abscess caused by Streptococcus pyogenes and Staphylococcus aureus bacteria are related to skin and skin structure infections, treated by this medicine.

    Pneumonia

    Infection and inflammation to the respiratory air sacs of lungs called pneumonia caused by bacteria. This medicine is used to treat this bacterial infection.


    Tigebax 50mg Injection Indication

    The Tigebax 50mg injection is prescribed in the following indications as Intraabdominal infections, Skin and skin structure infections, and Pneumonia


    Mechanism of action of Tigebax 50mg Injection

    Tigebax 50mg injection containing Tigecycline is a Glycylcycline antibiotic that produces its action by inhibiting the protein synthesis which is essential for the bacteria to function and it also prevents the infection from spreading.


    How Tigebax 50mg Injection works

    Tigebax 50mg injection containing Tigecycline is a Glycylcycline antibiotic that produces its action by inhibiting the protein synthesis which is essential for the bacteria to function and it also prevents the infection from spreading.


    Tigebax 50mg Injection Contraindication

    •  
    • Do not take this medicine if you are allergic to Tigecycline
    • It is contraindicated to use this medicine in patients who are having a history of renal and hepatic impairment
    • Kindly avoid using this medicine during 2nd and 3rd trimesters


    Tigebax 50mg Injection Side Effects

    • Diarrhea
    • Infection
    • Fever
    • Hypertension
    • Anemia
    • Dizziness
    • Dyspnea
    • Pruritus
    • Insomnia
    • Hypofibrinogenemia
    • Hepatic cholestasis
    • Jaundice
    • Acute pancreatitis


    FAQs for Tigebax 50mg Injection

    • How long does Tigebax 50mg injection take to work?

    Usually, the medicine produces its effect as soon as you consume it. But it may take some days to kill the bacteria

    • Can the use of Tigebax 50mg injection cause diarrhea?

    Yes, the use of this medicine can cause diarrhea because it is an antibiotic that kills both good and bad bacteria in your stomach as well as in your intestine and leads to diarrhea. Kindly consult your doctor if your symptom persists.

    • What if I do not get better after using the Tigebax 50mg injection?

    If you do not feel better after completing the full course of treatment kindly inform your doctor.


    Precautions and general warning of Tigebax 50mg Injection

    Alcohol

    The use of alcohol does not produce harmful effects while you are receiving this treatment. Kindly consult with your doctor.

    Driving or operating machinery

    It is considered unsafe to drive while you are receiving this medicine it may affect your ability to drive. Kindly consult with your doctor.

    Pregnancy

    The use of this medicine is considered unsafe during pregnancy because it may produce any harmful effects on the fetus. Kindly consult with your doctor

    Breast Feeding

    The use of this medicine is considered unsafe during breastfeeding because it may excrete via breast milk. Kindly consult with your doctor

    Kidney Problem

    It is considered safe to use this medicine in patients who are having renal diseases. It does not require any dose modification. Kindly consult with your doctor.

    Liver Disease

    The medicine should be used with caution in patients with hepatic impairment. The use of this medicine required dose modification. Kindly consult with your doctor.


    How to Take Tigebax 50mg Injection

    This injection comes in an intravenous dosage form and shakes well before use. It is injected by a health care professional in doctor clinics, hospitals. Use the injection as prescribed by your doctor. Do not discontinue the medicine when you feel better kindly consult together with your doctor.


    Use of Tigebax 50mg Injection in Adult

    It is considered to be safe to use this medicine in an adult patient if the drug is prescribed by a doctor. Kindly consult with your doctor.


    Use of Tigebax 50mg Injection in children

    It is not clear the safety and efficacy of the medicine in children who are below 18 years old. Kindly consult with your doctor.


    Use of Tigebax 50mg Injection in Elderly Patients

    Tigebax 50mg injection should be used with caution in patients with an elderly age group, which leads to developing further medical problems, leads to worsening the patient's health conditions. Kindly consult with your doctor. Dose modification or replacement is required based on the medical conditions of the patient.


    Other general warnings

    • Therapy should be administered with caution in patients who are having severe hepatic impairment and pregnancy
    • Kindly avoid using tigecycline during tooth development because it may lead to tooth enamel hypoplasia or permanent teeth discoloration
    • The use of medicine may cause hypofibrinogenemia, pancreatitis, and Clostridium difficile associated colitis
    • The use of this medicine may cause adverse effects to include photosensitivity, pseudotumor cerebri, and antianabolic action
    • The use of IV tigecycline increase the risk of mortality

    Diarrhea

    This medicine kills the good helpful bacteria in your stomach or intestine and causes diarrhea. It leads to worsening the patient’s health condition. Better to take probiotics with this medicine to avoid diarrhea.

    Antibiotic resistance

    Finish the complete course of antibiotics even if you feel better. Otherwise, it will lead to Antibiotic resistance (the bacteria may be resistant to antibiotics). After taking of complete course not feel better.


    Talk to your doctor if

    • You have a history of gastrointestinal disease
    • You are not responding to the treatment
    • You have experienced any allergic reaction like rashes and itching
    • You have severe stomach pain, diarrhea, severe headache, ringing in your ears, dizziness, nausea, vision problems, pain behind your eyes


    General instructions

    Tigebax 50mg injection contains Tigecycline used to treat severe bacterial infections such as Intraabdominal infections, Skin and skin structure infections, and Pneumonia. Tigecycline is an antibiotic that kills the bacteria and also helps to improve the symptoms and treat the infection. Mainly this bacterial infection targets the skin, intra-abdominal infection, and community-acquired pneumonia.


    Drug Interaction of Tigebax 50mg Injection

    Drug-Drug Interaction

    BCG vaccine live

    The use of this drug is contraindicated because the use of medicine decreases the effect of the BCG vaccine live by pharmacodynamic antagonism

    Dichlorphenamide

    Therapy should be administered with caution because the combination of this drug either increases the toxicity of the other by pharmacodynamic synergism and it also causes metabolic acidosis

    Estradiol

    Therapy should be administered with caution because the use of tigecycline decreases the effect of estradiol by altering the intestinal flora and it also lowers the risk of contraceptive failure.

    Warfarin

    Therapy should be administered with caution because the use of tigecycline increases the level of warfarin by decreasing its elimination.

    Mipomersen

    Therapy should be administered with caution because the combination of this drug either increases the toxicity of the other and it also increases the hepatic enzymes

    Drug-Food Interaction

    No interaction was available. Kindly consult with your doctor

    Drug-Disease Interaction

    Colitis

    This medicine kills the good helpful bacteria in your stomach or intestine and causes diarrhea. This drug should be used caution in patients with gastrointestinal disease, especially colitis (swelling of the colon inner lining). It leads to worsening the patient’s health condition.

    Liver diseases

    Therapy should be administered with caution in patients who are having severe liver disease because the use of tigecycline systemic clearance was reduced and half-life was prolonged.


    Over Dose

    Take the medicine as directed by the doctor don’t overdose on the medicine. If you have taken an overdose of this medicine immediately meet the doctor and rush to the nearby hospital.


    Missed Dose

    Take the medicine as directed by the doctor. Do not skip the medicine, if you forgot to take the medicine or missed the dose. It is almost time for your next dose, skip the missed dose and go back to your regular schedule. Don’t take the extra dose take the regular dose immediately. Don’t use the two-dose at one time (Double Dose).


    Storage and Disposal

    • Stored at 10-30°C room temperature.
    • Protect from light and heat.
    • Keep away from children and pets. Otherwise, it becomes toxic to them.
    • Disposed of properly in a suitable bag.
    •  


    Fast Tag

    • Tigecycline is a tetracycline antibiotic used to treat bacterial infections. It blocks the binding of bacterial cell wall synthesis which is essential for proteins required by bacteria to perform their vital functions
    • This medicine is not used for common flu and cold symptoms. And not treat viral infections. This medicine is commonly prescribed for cough and colds caused by bacterial and parasitic infections.
    • This medicine is contraindicated to allergic symptoms such as skin rash, itching, swelling, and breathing difficulties.