Drug Interaction of Tobacin 80mg Injection
BCG vaccine live
The use of this drug is contraindicated because the use of medicine decreases the effect of the BCG vaccine live by pharmacodynamic antagonism
Use alternative drugs, because the use of the cholera vaccine with antibiotics may activate the vaccine strain. So, avoid receiving this combination of medicines before 14 days of vaccination
The use of this medicine is contraindicated because the combination of this medicine may increase nephrotoxicity and Ototoxicity
Use alternative drugs because the use of tobramycin increases the effect of atracurium by pharmacodynamic synergism and it also increases the risk for developing apnea.
Use alternative drugs because the use of quinidine will increase the effect of tobramycin by P-glycoprotein efflux transporter.
Therapy should be administered with caution because the use of tobramycin decreases the effect of estradiol by altering the intestinal flora and it also lowers the risk of contraceptive failure.
Limited information is available kindly consult with your doctor.
Adequate hydration is required to prevent the risk of oto and nephrotoxicity that is associated with an aminoglycoside. Before initiating the treatment kindly correct your dehydration.
Therapy should be administered with caution in patients who are having neuromuscular disorders such as myasthenia gravis, parkinsonian syndrome, and botulism because the use of this medicine may cause dose-related muscle weakness and neuromuscular blockade.
Therapy should be administered with caution because the use of aminoglycoside may lead to nerve damage in the eighth cranial nerve which results in vestibular and auditory toxicities. Symptoms include dizziness, nystagmus, vertigo, ataxia, tinnitus, and hearing impairment.
Therapy should be administered with caution in patients with renal impairment due to the accumulation of the drug which leads to nephrotoxicity like tubular necrosis, increase in BUN, nonprotein nitrogen, serum creatinine concentration, decrease urine gravity and creatinine clearance, and proteinuria.