Brand Name Toppen-IT Tablet SR
Salt Composition

Pantoprazole (40mg) + Itopride (150mg)

Strength 40mg + 150mg
Product Form Tablet
Pack 10 Tablet(s) in Strip
Storage Store below 30°C
Category

Gastro Intestional Tract

SubCategory

anti-ulcer

Country of Origin India
Manufacturer

BMW Pharmaco India Pvt. Ltd.

Manufacturer/Marketer Address BMW Pharmaco India Pvt. Ltd., BMW HOUSE" 15/3, BMW Street, Lalpur Road, Gwarighat, Jabalpur - 482008 Madhya Pradesh, India
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M.R.P : Rs.120.00       Price : Rs.103.20

You Save : Rs.16.80    Inclusive of all taxes

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10 Tablet(s) in Strip

Availability : In Stock


    Medical Description of Toppen-IT Tablet SR

    Toppen-IT Tablet SR contains Pantoprazole 40mg and Itopride 150mg. Pantoprazole is a proton pump inhibitor (PPI), an anti-ulcer agent used to relieve acid-related indigestion, and heartburn in the stomach. Itopride is a benzamide derivative that acts as a prokinetic, which works on the upper digestive tract, allows food easily through the stomach.

    This tablet is contraindicated to allergic symptoms such as skin rashes, itching, swelling, breathing difficulties, etc, liver dysfunction, vitamin, and mineral deficiency, osteoporosis, or bone fractures.


    Toppen-IT Tablet SR Uses

    Used in the treatment of the following conditions as Peptic ulcer disease and Gastroesophageal reflux disease (GERD).


    Toppen-IT Tablet SR Benefits

    Gastroesophageal reflux disease (GERD)

    GERD occurs due to stomach acid frequently flows backwards direction from the stomach to the oesophagus, which leads to developing heartburn, and acid indigestion. Primarily it can manage lifestyle changes, and using OTC (Over the counter) medicines. Also, sometimes need surgery. This medicine is used to treat this backflow acid secretion in the stomach.


    Toppen-IT Tablet SR Indication

    Toppen-IT Tablet SR is used in the treatment of the following conditions as Peptic ulcer and Gastroesophageal reflux disease (GERD).

    Pantoprazole is a proton pump inhibitor (PPI), an anti-ulcer agent used to relieve acid-related indigestion, and heartburn in the stomach. Itopride is a benzamide derivative that acts as a prokinetic, which works on the upper digestive tract, allows food easily through the stomach. Swallow the whole tablet at once. Don’t break, chewed, or crushed the tablet.


    Mechanism of action of Toppen-IT Tablet SR

    Toppen-IT Tablet SR contains Pantoprazole 40mg and Itopride 150mg. This tablet shows an effect on the dopaminergic receptors without causing any release of the chemical dopamine. Itopride decreases bowel movement facilitates gastric emptying. Pantoprazole blocks the acid releasing gastric parietal cell of the stomach. A parietal cell of the stomach contains H+/K+ ATP Pumps which helps in acid secretion. Pantoprazole inhibits acid production by blocking these H+K+ ATP pumps, which results in the blocking of acid secretion.


    How Toppen-IT Tablet SR works

    Pantoprazole is a proton pump inhibitor(PPI), works by inhibiting the action of proton pumps (presented in the parietal cells of the stomach, involves acid secretion). Then it decreases the acid secretion from the stomach.

    Itopride is a prokinetic that works on the upper digestive tract, allows food easily through the stomach, and facilitates gastric emptying.


    Toppen-IT Tablet SR Contraindication

    Interaction with drug:

    Methotrexate

    Methotrexate is an antimetabolite used to treat rheumatoid arthritis. This medicine alters the action of methotrexate. Consult your doctor before taking any medication to improve your quality of life.

    Warfarin

    Warfarin is an anticoagulant drug. This medicine increases the levels of warfarin in our body leads to an increase in INR levels. It leads to a risk of serious bleeding. Consult your doctor before taking any medication to improve your quality of life.

    Nelfinavir

    Nelfinavir is an antiviral drug. This medicine alters the action of nelfinavir. Consult your doctor before taking any medication to improve your quality of life.

    Digoxin

    Digoxin is a cardiac glycoside used to treat irregular heartbeats. This medicine alters the action of digoxin. Consult your doctor before taking any medication to improve your quality of life.

    Rifampicin

    Rifampicin is a first-line antitubercular drug used to treat tuberculosis. This medicine alters the action of rifampicin. Consult your doctor before taking any medication to improve your quality of life.

    Interaction with disease:

    Kidney disease

    It should be used with caution in patients with renal impairment, or kidney diseases. Then it leads to a risk of kidney dysfunction or kidney damage. Consult your physician, and then take steps to improve your life. Dose modification or replacement is required based on the medical circumstances of the patient.

    Liver disease

    It should be used with caution in patients with hepatic dysfunction; hepatic impairment, or liver diseases. Then it leads to a risk of liver dysfunction or liver damage. Consult your physician, and then take steps to improve your life. Dose modification or replacement is required based on the medical circumstances of the patient.

    Osteoporosis

    It is a bone disease, becomes bones weak. Long-term use of pantoprazole can cause calcium deficiency, which leads to showing an effect on bones. Calcium and vitamin D supplements are given with this medicine to minimize this calcium and vitamin deficiency. Consult your doctor before taking any medication to improve your quality of life.

    Hypomagnesemia

    By long-term use of this medicine leads to develop hypomagnesemia (low magnesium levels), leads to developing dizziness, shivering, muscle pain, irregular heartbeat, seizures, or fits. Consult your physician, and then take steps to improve your life. Dose modification or replacement is required based on the medical circumstances of the patient.


    Toppen-IT Tablet SR Side Effects

    • Diarrhea
    • Stomach pain
    • Headache
    • Flatulence
    • Dizziness
    • Nausea
    • Vomiting
    • Dry skin
    • Skin rash, or itching
    • Constipation
    • Increased saliva production


    FAQs for Toppen-IT Tablet SR

    Does Toppen-IT (Pantoprazole (40mg) + Itopride (150mg)) Tablet SR have a habit-forming drug?

    No, Toppen-IT Tablet SR doesn’t have a habit-forming tendency.

    What is the time duration for Toppen-IT Tablet SR to react on the body?

    Toppen-IT Tablet SR shows its action within an hour after administration.

    How long Toppen-IT Tablet SR will sustain in our body?

    Toppen-IT Tablet SR remains for 24 hours in our body.

    Is it safe during pregnancy?

    No. Toppen-IT Tablet SR is not safe during pregnancy. Toppen-IT Tablet SR shows an effect on the fetus. Consult your doctor before taking any medication to improve your quality of life.

    Can we take over years of time?

    Long-term use of this medicine leads to develop bone fractures, vitamin, and mineral deficiencies. Consult your doctor before taking any medication to improve your quality of life.


    Precautions and general warning of Toppen-IT Tablet SR

    Alcohol

    No results were found, not get proper information. By using alcohol leads to develop acidity, which leads to worsening the patient health conditions. Consult your doctor before taking any medication to improve your quality of life.

    Driving or operating machinery

    No. Toppen-IT Tablet SR is not safe to drive after administration. This combination tablet causes drowsiness, sleepiness, and alters the ability to drive. Consult your doctor before taking any medication to improve your quality of life.

    Pregnancy

    No. This tablet is not safe during pregnancy. This combinational tablet shows an effect on the fetus. Consult your doctor before taking any medication to improve your quality of life.

    Breast Feeding

    No. Toppen-IT Tablet SR is not safe during breastfeeding. It shows an effect on the babies, secreted through breast milk. Consult your doctor before taking any medication to improve your quality of life.

    Kidney Problem

    This tablet should be used with caution in patients with renal impairment, or kidney diseases. Then it leads to the risk of kidney dysfunction or kidney damage. Consult your physician, and then take steps to improve your life. Dose modification or replacement is required based on the medical circumstances of the patient.

    Liver Disease

    This tablet should be used with caution in patients with hepatic dysfunction; hepatic impairment, or liver diseases. Then it leads to a risk of liver dysfunction or liver damage. Consult your physician, and then take steps to improve your life. Dose modification or replacement is required based on the medical circumstances of the patient.


    How to Take Toppen-IT Tablet SR

    This tablet should be taken on an empty stomach, at least one hour before the meal as prescribed by the doctor. Take this medicine at a fixed time intervals. It is better, try to finish your dinner three hours before going to bed, for reducing the acid secretion in the stomach.

    Take the correct dose and duration of medicine as prescribed by the doctor. Swallow the whole tablet at once. Don’t break, chewed, or crushed the tablet.


    Use of Toppen-IT Tablet SR in Adult

    Consult your physician.


    Use of Toppen-IT Tablet SR in children

    Toppen-IT Tablet SR is not prescribed in children under 16 years of age.


    Use of Toppen-IT Tablet SR in Elderly Patients

    Toppen-IT Tablet SR should be used with caution in patients with an elderly age group, which leads to developing further medical problems, leads to worsening the patient health conditions. Consult your physician, and then take steps to improve your life. Dose modification or replacement is required based on the medical circumstances of the patient.


    Other general warnings

    If you are allergic to this combination medicine. Informed the doctor before prescribing this medicine. If you noticed any allergic symptoms such as skin rashes, itching, swelling, breathing difficulties, etc. Immediately meet your doctor, for a better quality of a life.


    Talk to your doctor if

    Consult your physician.


    General instructions

    Toppen-IT (Pantoprazole (40mg) + Itopride (150mg)) Tablet SR is used in the treatment of the following conditions as Gastroesophageal reflux disease (GERD).

    Pantoprazole is a proton pump inhibitor (PPI), an anti-ulcer agent used to relieve acid-related indigestion, and heartburn in the stomach. Itopride is a benzamide derivative that acts as a prokinetic, which works on the upper digestive tract, allows food easily through the stomach.


    Drug Interaction of Toppen-IT Tablet SR

    Drug-Drug Interaction

    Methotrexate

    Methotrexate is an antimetabolite used to treat rheumatoid arthritis. This medicine alters the action of methotrexate. Consult your doctor before taking any medication to improve your quality of life.

    Warfarin

    Warfarin is an anticoagulant drug. This medicine increases the levels of warfarin in our body leads to an increase in INR levels. It leads to a risk of serious bleeding. Consult your doctor before taking any medication to improve your quality of life.

    Nelfinavir

    Nelfinavir is an antiviral drug. This medicine alters the action of nelfinavir. Consult your doctor before taking any medication to improve your quality of life.

    Digoxin

    Digoxin is a cardiac glycoside used to treat irregular heartbeats. This medicine alters the action of digoxin. Consult your doctor before taking any medication to improve your quality of life.

    Rifampicin

    Rifampicin is a first-line antitubercular drug used to treat tuberculosis. This medicine alters the action of rifampicin. Consult your doctor before taking any medication to improve your quality of life.

    Drug-Food Interaction

    By using this medicine with food should be maintained time gap at least 1 hour before the meals for better effectiveness of the medicine. By using this medicine with spicy, fatty foods, alcohol, caffeinated drinks, or beverages such as coffee, tea, cola, etc, should be avoided for better effectiveness of the medicine.

    Drug-Disease Interaction

    Kidney disease

    It should be used with caution in patients with renal impairment, or kidney diseases. Then it leads to a risk of kidney dysfunction or kidney damage. Consult your physician, and then take steps to improve your life. Dose modification or replacement is required based on the medical circumstances of the patient.

    Liver disease

    It should be used with caution in patients with hepatic dysfunction; hepatic impairment, or liver diseases. Then it leads to a risk of liver dysfunction or liver damage. Consult your physician, and then take steps to improve your life. Dose modification or replacement is required based on the medical circumstances of the patient.

    Osteoporosis

    It is a bone disease, becomes bones weak. Long-term use of pantoprazole can cause calcium deficiency, which leads to showing an effect on bones. Calcium and vitamin D supplements are given with this medicine to minimize this calcium and vitamin deficiency. Consult your doctor before taking any medication to improve your quality of life.

    Hypomagnesemia

    By long-term use of this medicine leads to develop hypomagnesemia (low magnesium levels), leads to developing dizziness, shivering, muscle pain, irregular heartbeat, seizures, or fits. Consult your physician, and then take steps to improve your life. Dose modification or replacement is required based on the medical circumstances of the patient.


    Over Dose

    Take the doses properly as directed by the doctor. Do not be taken as an overdose. If you are taken, unfortunately, immediately meet the doctor, for a better quality of life.


    Missed Dose

    Probably do not skip the dose as directed by the doctor. If you skipped the dose, take it immediately. If you skipped the dose, it’s nearer to the next dose, take properly one dose, do not be taken as double the dose. It leads to overdose, immediately meet the doctor, for a better life.


    Storage and Disposal

    Stored at 10-30°C room temperature.

    Protect from light and heat.

    Keep away from children and pets. Otherwise, it becomes toxic to them.

    Disposed of properly in a suitable bag.


    Fast Tag

    Toppen-IT Tablet SR contains Pantoprazole 40mg and Itopride 150mg. Pantoprazole is a proton pump inhibitor (PPI), an anti-ulcer agent used to relieve acid-related indigestion, and heartburn in the stomach. Itopride is a benzamide derivative that acts as a prokinetic, which works on the upper digestive tract, allows food easily through the stomach.

    Likewise, it is better, try to finish your dinner three hours before going to bed, for reducing the acid secretion in the stomach.