Tyronib 100mg Tablet
Brand Name | Tyronib 100mg Tablet |
Salt Composition |
Imatinib (100mg) |
Strength | 100mg |
Product Form | Tablet |
Pack | 10 Tablet(s) in Strip |
Storage | Store below 30°C |
Category |
Anti-Cancer |
SubCategory |
Blood Cancer |
Country of Origin | India |
Manufacturer |
Taj Pharma India Ltd |
Manufacturer/Marketer Address | Taj Pharma India Ltd, First Floor, 15-6-108, Afzal Gunj, Hyderabad, Telangana, 500012 |
You Save : Rs.230.00 Inclusive of all taxes
- Chronic myeloid leukemia in children and adults
- Acute lymphoblastic leukemia in children and adults
- Gastrointestinal stromal tumors in adults
- Decreased hemoglobin
- Fluid retention
- Diarrhea
- Fatigue
- Nausea
- Abdominal pain
- Increased liver enzymes
- Muscle spasms
- Increased blood creatinine
- Dermatitis
- Hemorrhage
- Peripheral edema
- Upper respiratory tract infection
- Dizziness
- Flatulence
- Increased weight
- Facial edema
- Does Tyronib 100mg Tablet cause hair loss?
- Is Tyronib 100mg Tablet a vesicant or chemotherapeutic drug?
- Can I stop using the Tyronib 100mg Tablet immediately or do I have to slowly wean off the use?
- The use of this medicine increases the risk of developing severe congestive heart failure
- Hypothyroidism was reported
- The use of this medicine may cause a cardiac adverse reaction like cardiomyopathy, congestive heart failure, diastolic dysfunction, fatal myocardial infarction, left ventricular dysfunction, and Tumor lysis syndrome
- The use of this medicine may increase the risk of developing fluid retention and pleural and pericardial effusion
- Embryofetal toxicity was reported
- You are not responding to the treatment
- You have experienced any allergic reaction like rashes and itching
- You have a receiving any concomitant medication and disease
- Stored at 10-30°C room temperature.
- Protect from light and heat.
- Keep away from children and pets. Otherwise, it becomes toxic to them.
- Disposed of properly in a suitable bag.
- Tyronib 100mg Tablet contains Imatinib 400mg used to treat chronic myelocytic leukemia, Gastrointestinal stromal tumor, and acute lymphocytic leukemia by inhibiting the activity of an abnormal protein that signals the cancer cells to multiply and it also helps to stop the growth of cancer cells.
- Kindly use birth control to avoid pregnancy while you are receiving this medicine.
- Inform your doctor if you have experienced any bleeding, dark tarry or bloody stools, and sore throat
Medical Description of Tyronib 100mg Tablet
Tyronib 100mg Tablet contains Imatinib 100mg used to treat chronic myelocytic leukemia, Gastrointestinal stromal tumor, and acute lymphocytic leukemia by inhibiting the activity of an abnormal protein that signals the cancer cells to multiply and it also helps to stop the growth of cancer cells. It is used in patients whose disease cannot be treated with other medications.
Tyronib 100mg Tablet Uses
It is used in the treatment of the following conditions chronic myelocytic leukemia, Gastrointestinal stromal tumor, and acute lymphocytic leukemia.
Tyronib 100mg Tablet Benefits
Chronic myeloid leukemia:
It is also called chronic myelogenous leukemia. This cancer occurs in the bone marrow and causes an increase in white blood cells. It occurs due to genetic changes in the stem cells which are produced by the bone marrow. Symptoms include easy bleeding, fever, weight loss, loss of appetite, night sweats, fatigue, and bone pain.
Acute lymphoblastic leukemia:
It is a cancer of blood and bone marrow that affects white blood cells. It usually occurs when a cell in bone marrow develops changes in its DNA. Symptoms include fever, joint pain, severe nosebleeds, pale skin, shortness of breath, fatigue, and bleeding from the gums.
Gastrointestinal Stromal tumor:
It is a soft tissue sarcoma that is located in any part of your digestive system. Symptoms include weight loss, difficulty in swallowing, abdominal pain, anemia, vomiting, and blood in stools.
Tyronib 100mg Tablet Indication
The Tyronib 100mg Tablet is prescribed in the following indications as
Mechanism of action of Tyronib 100mg Tablet
Tyronib 100mg Tablet contains Imatinib is an anti-cancer medication, tyrosine kinase inhibitor that produces its effect by inhibiting BCR-ABL, PDGFR, and c-Kit kinase containing receptors present on abnormal cells thus the signaling process for angiogenesis and proliferation of abnormal cells is inhibited and it also minimizes the growth of abnormal cancer cells and terminates metastasis of tumors or cancers.
How Tyronib 100mg Tablet works
Tyronib 100mg Tablet contains Imatinib is an anti-cancer medication, tyrosine kinase inhibitor that produces its effect by inhibiting BCR-ABL, PDGFR, and c-Kit kinase containing receptors present on abnormal cells thus the signaling process for angiogenesis and proliferation of abnormal cells is inhibited and it also minimizes the growth of abnormal cancer cells and terminates metastasis of tumors or cancers.
Tyronib 100mg Tablet Contraindication
if you are allergic to Tyronib 100mg (imatinib 100mg) Tablet or its constituents
Tyronib 100mg Tablet Side Effects
FAQs for Tyronib 100mg Tablet
Yes, one of the common side effects of this medicine is hair loss. Kindly consult with your doctor if your symptoms even persist after withdrawal of the medicines.
It is a chemotherapeutic drug used for the management of cancer
You should not withdraw the medicine immediately, you should taper the dose to avoid rebound effects.
Precautions and general warning of Tyronib 100mg Tablet
Alcohol
It is not clear that consuming alcohol is safe while you are receiving this medicine. Kindly consult with your doctor
Driving or operating machinery
It is considered unsafe to drive while you are receiving this medicine it may affect your ability to drive. Kindly consult with your doctor.
Pregnancy
The use of this medicine is considered unsafe during pregnancy because it may produce any harmful effects. Kindly consult with your doctor
Breast Feeding
The use of this medicine is considered unsafe during breastfeeding because it may produce any harmful effects. Kindly consult with your doctor
Kidney Problem
Therapy should be administered with caution in patients who are having kidney impairment. Adjust the dose as per the requirement. Kindly consult with your doctor.
Liver Disease
Therapy should be administered with caution in patients who are having a hepatic impairment. Adjust the dose as per the requirement. Kindly consult with your doctor.
How to Take Tyronib 100mg Tablet
The Tablet is taken orally with food. You should not chew, cut or crush the tablet. Initially start with a low dose and slowly increase the dose once every week. Follow the direction mentioned within the label if you probably did not understand the appliance kindly ask your doctor or pharmacist to elucidate in detail. Do not withdraw the medicine when you feel better kindly complete the course of treatment to avoid reoccurrence.
Use of Tyronib 100mg Tablet in Adult
It is considered to be safe to use this medicine in an adult patient if the drug is prescribed by a doctor. Kindly consult with your doctor
Use of Tyronib 100mg Tablet in children
Safety and efficacy were not established in children who are below 1 year old. Kindly consult with your doctor.
Use of Tyronib 100mg Tablet in Elderly Patients
Tyronib 100mg Tablet should be used with caution in patients with an elderly age group, which leads to developing further medical problems, leads to worsening the patient's health conditions. Kindly consult with your doctor. Dose modification or replacement is required based on the medical conditions of the patient.
Other general warnings
Talk to your doctor if
General instructions
Tyronib 100mg Tablet is used to treat chronic myelocytic leukemia, Gastrointestinal stromal tumor, and acute lymphocytic leukemia by inhibiting the activity of an abnormal protein that signals the cancer cells to multiply and it also helps to stop the growth of cancer cells. It is used in patients whose disease cannot be treated with other medications.
Drug Interaction of Tyronib 100mg Tablet
Drug-Drug Interaction
Dihydroergotamine + Imatinib
The use of this is contraindicated because the use of Imatinib will increase the effect of dihydroergotamine by affecting patient hepatic and intestinal enzyme metabolism.
Deferiprone + Imatinib
Use alternative drug because the combination of this medicine either increase the toxicity of the other by pharmacodynamic synergism
Erdafitinib + Imatinib
Use alternative drugs because the use of erdafitinib will increase the effect of imatinib by P-glycoprotein efflux transporter.
Acetaminophen + Imatinib
Therapy should be administered with caution because the use of imatinib decreases the effect of acetaminophen by decreasing its hepatic clearance
Drug-Food Interaction
The use of grapefruit juice increases the blood level of imatinib and also increases the risk of side effects such as dizziness, confusion, hallucinations, mood changes, insomnia, drowsiness, congestive heart failure, and QT prolongation.
Drug-Disease Interaction
Cardiovascular diseases:
Therapy should be administered with caution because the use of multiple kinase inhibitors causes arterial vascular occlusive events, peripheral arterial occlusive events, and ischemic cerebrovascular events.
Fluid retention:
Therapy should be administered with caution in patients who are having fluid retention because the use of multiple tyrosine kinase inhibitors may cause pericardial effusion, pleural effusion, pulmonary edema, and peripheral edema.
Bone marrow suppression:
Therapy should be administered with caution in patients with bone marrow suppression because the use of multiple tyrosine kinase inhibitors may cause thrombocytopenia, aplastic anemia, agranulocytosis, and neutropenia.
Hepatic impairment:
Therapy should be administered with caution in patients with hepatic impairment. Monitor the patient hepatic function during the treatment.
Over Dose
Take the medicine as directed by the doctor don’t overdose on the medicine. If you have taken an overdose of this medicine immediately meet the doctor and rush to the nearby hospital.
Missed Dose
Take the medicine as directed by the doctor. Do not skip the medicine, if you forgot to take the medicine or missed the dose. It is almost time for your next dose, skip the missed dose and go back to your regular schedule. Don’t take the extra dose take the regular dose immediately. Don’t use the two-dose at one time (Double Dose).
Storage and Disposal
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