X Vir 0.5mg Tablet

X.vir 0.5Mgcontains its active substance called Entecavir. Entecaviris an antiviral medicine used in the treatment of chronichepatitis B infection. It is a guanine nucleoside analogue. It is used in compensated and decompensated liver diseases.

X.vir 0.5Mg is used to treat adults and children above 2 years of age who are infected by Hepatitis B virus. X.vir 0.5Mgshould not be taken separately if you are HIV positive. X.vir 0.5Mgcan be taken with other anti-HIV medications. X.vir 0.5Mgcan be used in cases with compensated and decompensated liver diseases.

X.vir 0.5Mg Tablet used in the treatment for the following condition like 

Chronic hepatitis B virus infection:

It is a chronic liver infection that is caused by the hepatitis B virus. It usually occurs when our body cannot fight against the virus and it is a communicable disease. It is caused by sexual contact with an infected person, sharing needles, and it also spread from mother to child during pregnancy and breastfeeding.

X.vir 0.5Mgis indicated in case of chronic HBV infection.X.vir 0.5Mgis co-administeredsafely with other antiretrovirals for HIV. X.vir 0.5Mgis indicated in ages above 2 years of age.

X.vir 0.5Mgcontains its active substance called Entecavir. Entecavir is guanosine nucleoside analogue.Entecavir acts against HBV polymerase. It competes with deoxyguanosine triphosphate and entecavir triphosphate inhibits all functions of HBV polymerase which is required for replication of virus. Thus, treats HBV infection.

X.vir 0.5Mgis HIV-1 guanosine nucleoside analogue. X.vir 0.5Mginhibits the action of HBV polymerase by incorporating themselves into the nucleotide sequence thus inhibits the action of HBV polymerase, thereby preventing the formation of mature virus particles. Thus, controls and treats HBV infection.

Absolute contraindications:

• if you are allergic to Hepalo 0.5Mg.
• if you have renal diseases
• if you are pregnant
• if you are diabetic
• if you have liver metabolism disorders

common side effects that occur 1:100 patients: headache, insomnia, fatigue, dizziness, somnolence, vomiting, diarrhoea, nausea, dyspepsia, and increased blood levels of liver enzymes.Decreased levels of neutrophils

uncommon side effects that occur 1:1000 patients:rash, hair loss, hematuria

rare side effects that occur 1:10,000 patients: severe allergic reaction, lactic acidosis

• Is X.vir 0.5Mgsafe during pregnancy?

No, taking X.vir 0.5Mgduring pregnancy is not recommended. Consult your physician.

• Can X.vir 0.5Mgbe taken while breast feeding?

No, taking X.vir 0.5Mgis not recommended during breast feeding. Consult your physician.

• Can X.vir 0.5Mgbe taken while alcohol consumption?

The interaction is unknown but this medication causes side effects. Thus, consult your physician.

• Can I take drive or operate heavy machineries while on Hepalo 0.5Mg?

This medication causes side effects thus caution is used while driving or operating machineries.

• Can X.vir 0.5Mgbe taken as a treatment for HIV?

No, X.vir 0.5Mgis not an antiretroviral but it can be used with other antiretrovirals that treat HIV infection

Alcohol

X.vir 0.5Mggenerally causes side effects thus it is advised not to be taken with alcohol. For further queries, consult your physician.

Driving or operating machinery

It is preferred to drive or operate heavy machinery with caution as X.vir 0.5Mgcauses side effects. For further queries, consult your physician.

Pregnancy

The use of X.vir 0.5Mgis not recommended during pregnancy.

Breast Feeding

The use of X.vir 0.5Mgduring breastfeeding is not recommended.

Kidney Problem

renal filtration impairment – monitor function. For further queries, consult your physician.

Liver Disease

Compensated and decompensated liver disease

Monitor liver function before and during therapy, especially in patients with other

Exacerbation of hepatitis after completion of treatment

X.vir 0.5Mgis used in children above 2 years of age or 10 Kgs of weight in naïve cases

                Upto 30 kgs – 0.5mg/d

                >30 kgs – 1mg/d

X.vir 0.5Mgused in children above 2 years of age or 10 Kgs of weight in pre-exposed cases, the dosage is doubled.

X.vir 0.5Mgcan be taken with other antiretrovirals as prescribed by the physician without fail. These drugs must be taken with or without food on a regular time basis.

If you are pregnant or breastfeeding inform your physician as they are not advisable.

The recommended dosage of X.vir 0.5Mgin compensated liver disease is 0.5mg/d in naïve cases

The recommended dosage of X.vir 0.5Mgin compensated liver disease is 1mg/d in pre-exposed cases

The recommended dosage of X.vir 0.5Mgin decompensated liver disease is 1mg/d

X.vir 0.5Mgcan be taken with other antiretrovirals as prescribed by the physician without fail. These drugs must be taken with or without food on a regular time basis.

• Skin reactions - It can be mild to severe like Stevens-Johnson Syndrome and toxic epidermal necrolysis.
• New onset diabetes mellitus or hyperglycemia – Monitor blood glucose and insulin levels.
• Lactic acidosis

If you have any allergy

If you have a liver problem

If you have a kidney problem

If you are diabetic

If you are pregnant or breastfeeding

X.vir 0.5Mgis taken orally as prescribed dosage at specific time regularly. It can be safely used in cases of HIV cases who are on a regime

Drug-Drug Interaction

Alendronate/amikacin/amiloride/azilsartan

benazepril

candesartan/captopril/cidofovir/creatine /cyclosporine

diflunisal

enalapril/eprosartan/ethacrynic acid/etidronate

foscarnet/fosinopril

gallium nitrate/ganciclovir/gentamicin

ibandronate/irbesartan

kanamycin

letermovir/lisinopril/losartan

mannitol/mefenamic acid/mesalamine

neomycin

Olmesartan/oxaliplatin

Pamidronate /pentamidine/perindopril/pindolol /polymyxin B/procainamide

quinapril

ramipril/risedronate/

sacubitril/streptomycin/sulindac

tacrolimus/telavancin/telmisartan/tobramycin/trandolapril/triamterene

valganciclovir/valsartan

zoledronic acid/zonisamide

Contact your doctor, pharmacist or nurse immediately.

If you take once a day dosage, then the missed dosage if you notice within 12 hours. If it is more than 12 hours, then skip the dosage and take the next doses as usual.

If you take twice a day dosage, then the missed dosage if you notice within 6 hours. If it is more than 6 hours, then skip the dosage and take the next doses as usual.

Always take with other antiretrovirals Don’t take a double dose for a forgotten dose.

Keep the medication out of children’s reach

Keep the medication away from pets

Once expired dispose immediately

Store at 30?C

X.vir 0.5Mgcontains its active substance called entecavir.

It is a nucleoside guanosine analogue.

It is used to control and treat HBV infection

Do not use this medication while lactation period.

Don’t use this medication with liver disease and kidney diseases.