Yoxicam 8mg/325mg Tablet

Yoxicam 8mg/325mg Tablet contains Lornoxicam 8mg and Paracetamol 325mg a pain-relieving medicine used to treat pain and inflammation, and swelling like rheumatoid arthritis, ankylosing spondylitis, and Osteoarthritis. It produces its action by inhibiting the release of chemical substances which cause pain and inflammation in your body.

It is used in the treatment of the pain

Pain relief

The use of this medicine helps to relieve moderate to severe pain in conditions like menstrual cramps, headaches, joints, muscles, rheumatoid arthritis, and osteoarthritis by inhibiting the chemical messengers in the brain.

The Yoxicam 8mg/325mg Tablet is prescribed for the following indications as pain reliever, rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, and toothaches.

Yoxicam 8mg/325mg Tablet contains Lornoxicam 8mg and Paracetamol 325mg. Lornoxicam and Paracetamol are analgesics and anti-inflammatory medications. It produces its action by inhibiting the release of chemical messengers which is responsible for pain and inflammation

Yoxicam 8mg/325mg Tablet contains Lornoxicam 8mg and Paracetamol 325mg. Lornoxicam and Paracetamol are analgesics and anti-inflammatory medications. It produces its action by inhibiting the release of chemical messengers which is responsible for pain and inflammation

• Do not take this medicine if you are allergic to Lornoxicam and Paracetamol
• It is contraindicated to use this medicine in patients with a history of asthma, urticaria, coronary artery bypass graft surgery, and severe liver diseases.

• Edema
• Headache
• Dizziness
• Abdominal pain
• Constipation
• Diarrhea
• Flatulence
• Heartburn
• GI ulcers
• Abnormal renal function
• Elevated liver enzymes
• Hepatotoxicity
• Live failure
• Pneumonitis
• Nephrotoxicity

• Can Yoxicam 8mg/325mg Tablet damage your kidneys?

Long-term use of this medicine may cause renal damage such as protein or blood in urine and painful urination. Kindly monitor the patient's kidney function.

• Is the Yoxicam 8mg/325mg Tablet a good painkiller?

Yes, the use of this medicine is considered an effective treatment to relieve pain and inflammation.

• Does the Yoxicam 8mg/325mg Tablet make you drowsy?

Yes, the use of this medicine makes you feel drowsy, fatigue and drowsiness but it is considered a common effect.

Alcohol

It is considered unsafe to consume alcohol while taking this medication. Kindly consult with your doctor

Driving or operating machinery

It is not clear whether the use of this medicine will affect your ability to drive. Kindly consult with your doctor.

Pregnancy

Limited information is available regarding the use of this medicine in patients during pregnancy. Kindly consult with your doctor.

Breast Feeding

Limited information is available regarding the use of this medicine in patients during breastfeeding. Kindly consult with your doctor.

Kidney Problem

It is considered safe to use this medicine in patients with kidney impairment. Kindly consult with your doctor.

Liver Disease

Limited information is available regarding the use of this medicine in patients with liver impairment. Kindly consult with your doctor.

The Tablet is taken orally on an empty stomach. You should not chew, cut or crush the tablet. Take this medicine as per the dose and duration advised by your doctor. Follow the direction mentioned within the label if you probably did not understand the appliance kindly ask your doctor or pharmacist to elucidate in detail. Do not withdraw the medicine when you feel better kindly complete the course of treatment to avoid reoccurrence.

It is considered to be safe to use this medicine in an adult patient if the medicine is prescribed by a doctor. Kindly consult with your doctor.

Yoxicam 8mg/325mg Tablet is considered unsafe in children who are below 12 years old. Kindly consult with your doctor.

Yoxicam 8mg/325mg Tablets should be used with caution in patients with an elderly age group, which leads to developing further medical problems, leads to worsening the patient's health conditions. Kindly consult with your doctor. Dose modification or replacement is required based on the medical conditions of the patient.

• Nonsteroidal anti-inflammatory drugs may increase the risk of developing cardiovascular thrombotic events, myocardial infarction, and stroke
• The use of this medicine also increases the risk of developing serious GI adverse events including bleeding, ulceration, and gastric perforation
• Therapy should be administered with caution in patients with bronchospasm, cardiac diseases, hepatic porphyria, hypertension, fluid retention, severe renal impairment, smoking, and systemic lupus erythematosus
• The use of this medicine decrease platelet aggregation and may prolong the bleeding time
• Therapy should be administered with caution in patients with blood dyscrasias, and bone marrow depression
• The use of this medicine may increase the risk of hyperkalemia and aseptic meningitis
• Therapy should be administered with caution in patients with severe hepatic impairment, renal impairment, chronic malnutrition, and G6PD deficiency.
• The use of this medicine increase the risk of developing hepatotoxicity, and serious skin reactions

• You have a history of gastrointestinal disease
• You are not responding to the treatment
• You have experienced any allergic reactions like rashes and itching
• You are suffering from anemia
• You have watery diarrhea, stomach pain, and fever

Lornoxicam 8mg and Paracetamol 325mg  is a pain-relieving medicine used to treat pain and inflammation, and swelling like rheumatoid arthritis, ankylosing spondylitis, and Osteoarthritis. It produces its action by inhibiting the release of chemical substances which cause pain and inflammation in your body.

Drug-Drug Interaction

Apixaban + Lornoxicam

The use of this drug is contraindicated because the combination of this drug increases the effect of anticoagulation

Captopril + Lornoxicam

Use alternative drug because the use of the non-steroidal anti-inflammatory drug may decrease the effectiveness of the antihypertensive drug and the combination of these drugs also decrease the renal functions

Aliskiren + Lornoxicam

Therapy should be administered with caution because the use of Lornoxicam will decrease the effect of aliskiren on other

Apalutamide + Paracetamol

Therapy should be administered with caution because the use of apalutamide will decrease the effect of acetaminophen by increasing its elimination.

Eltrombopog + Paracetamol 

Therapy should be administered with caution because the use of eltrombopag increases the levels of acetaminophen by decreasing its metabolism.

Isoniazid + Paracetamol 

Isoniazid will increase the effect of acetaminophen by affecting its hepatic enzyme metabolism. Therapy should be administered with caution.

Colestipol + Paracetamol 

Colestipol decreases the effect of acetaminophen by inhibiting GI absorption. Use alternative drugs.

Drug-Food Interaction

Alcohol

The use of alcohol should be avoided in patients who are taking this medicine because it may increase the risk of bleeding in the stomach which includes tarry, bloody stools, or coughing up blood while vomiting.  Do not withdraw the medication without consulting with the doctor

Drug-Disease Interaction

Asthma + Lornoxicam

Therapy should be administered with caution in patients who are having asthma because the use of the non-steroidal anti-inflammatory drug (NSAIDs) in asthma patients may cause nasal polyposis, pansinusitis, eosinophilia, and rhinitis. Before initiating the therapy ask the patients whether they are allergic to salicylate salts.

Heart failure+ Lornoxicam

Therapy should be administered with caution in patients with heart failure because the use of NSAIDs may cause fluid retention and edema

Hepatotoxicity + Lornoxicam

Therapy should be administered with caution in a patient with liver diseases because the use of NSAIDs may increase the serum transaminases, LDH, and alkaline phosphatase. And in rare cases, it may cause hepatotoxicity including liver cirrhosis, jaundice, and hepatic failure

Hypertension + Lornoxicam

Therapy should be administered with caution in patients with hypertension because the use of NSAIDs may increase blood pressure and cardiovascular events. During this course of treatment monitor the patient blood pressure

Renal toxicities + Lornoxicam

Therapy should be administered with caution in a patient with renal diseases because the use of NSAIDs may increase the serum creatinine, BUN, tubular necrosis, glomerulus, renal papillary necrosis, nephrotic syndrome, and cause renal failure.

Liver diseases +  Paracetamol 

Therapy should be administered with caution in patients with hepatic insufficiency because severe liver injury including acute liver failure resulting in liver transplant and death has been reported in patients using acetaminophen. Patients with hepatic impairment may increase the risk of toxicity due to increased metabolic pathway activity. During acetaminophen-containing treatment, patients should avoid consuming alcohol.

Alcoholism +  Paracetamol

Therapy should be administered with caution in patients who are consuming alcohol because severe liver injury including acute liver failure resulting in liver transplant and death has been reported in patients using acetaminophen. During acetaminophen-containing treatment, patients should avoid consuming alcohol. The patient should immediately seek the hospital if they experience signs and symptoms of liver injury such as fever, rash, anorexia, nausea, vomiting, fatigue, dark urine, and jaundice.

Take the medicine as directed by the doctor don’t overdose on the medicine. If you have taken an overdose on this medicine immediately meet the doctor and rush to the nearby hospital.

Take the medicine as directed by the doctor. Do not skip the medicine, if you forgot to take the medicine or missed the dose. It is almost time for your next dose, skip the missed dose and go back to your regular schedule. Don’t take the extra dose take the regular dose immediately. Don’t use the two-dose at one time (Double Dose).

• Stored at 10-30°C room temperature.
• Protect from light and heat.
• Keep away from children and pets. Otherwise, it becomes toxic to them.
• Disposed of properly in a suitable bag.

• Yoxicam 8mg/325mg Tablet contains  Lornoxicam 8mg and Paracetamol 325mg  is a pain-relieving medicine used to treat pain
• It produces its action by inhibiting the release of chemical substances which cause pain and inflammation in your body.
• Kindly inform your doctor if you have a history of heart disease or stroke
• The tablet is taken orally by mouth on an empty stomach
• Monitor the patient's kidney functions, liver function, and levels of blood components
• Avoid consuming alcohol because it may cause excessive drowsiness and stomach problems