Zentrom 250mg Injection

Brand Name Zentrom 250mg Injection
Salt Composition Artesunate (250mg)
Strength 250mg
Product Form Powder For Injection
Pack 1 Powder for Injection in 1 vial
Storage Store below 30°C
Category Antimalarial
Country of Origin India
Manufacturer Taj Pharma India Ltd
Manufacturer/Marketer Address Taj Pharma India Ltd, First Floor, 15-6-108, Afzal Gunj, Hyderabad, Telangana, 500012
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M.R.P : Rs.142.00       Price : Rs.113.60

You Save : Rs.28.40    Inclusive of all taxes

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1 Powder for Injection in 1 vial

Availability : In Stock

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    Medical Description of Zentrom 250mg Injection

    Zentrom 250mg Injection contains Artesunate 250mg used to treat Malaria. Artesunate 250mg is an antimalarial drug, results in interacting with certain substances which are required for the malarial parasite present in the blood to do its vital functions. Then it eradicates the malarial infection caused by Plasmodium falciparum strains of malarial parasite. It is particularly used to treat malaria disease (resistant to other antimalarial medicines). Also, used to treat uncomplicated malaria disease with a combination of other antimalarial medicines. This medicine does not prevent or treat severe malaria where it has affected the brain, lungs, and kidneys.


    Zentrom 250mg Injection Uses

    It is used in the treatment of the following conditions as parasitic infections such as Malaria


    Zentrom 250mg Injection Benefits

    Parasitic infections

    It is an organism that lives in another organism like your body for its food and place to survive. You can get a parasitic infection from contaminated water, food, bug bites o sexual contact. It is a one-celled organism called protozoa which can be seen in the naked eye. Symptoms include stomach pain, nausea, vomiting, dehydration, weight loss, inflamed lymph nodes, constipation, diarrhea, rashes, eczema, hives, muscle, and joint pain.

    Malaria

    Zentrom 250mg injection (Artesunate) is used to treat malaria disease caused by plasmodium falciparum strains of malarial parasite. Also, used to treat the malaria disease (resistant to other antimalarial medicines) which leads to developing a fever, chills, nausea, vomiting, headache, muscle pain, etc.


    Zentrom 250mg Injection Indication

    The Zentrom 250mg Injection is prescribed in the following indications as Malaria


    Mechanism of action of Zentrom 250mg Injection

    Zentrom 250mg Injection contains Artesunate 250mg is an antiparasitic medicine that produces its action by producing the free radicals (harmful substances) within the malarial parasite present in the blood this helps to kill the parasite.


    How Zentrom 250mg Injection works

    Zentrom 250mg Injection contains Artesunate 250mg is an antiparasitic medicine that produces its action by producing the free radicals (harmful substances) within the malarial parasite present in the blood this helps to kill the parasite.


    Zentrom 250mg Injection Contraindication

    • Do not take this medicine if you are allergic to Artesunate, Mefloquine, Quinine, and Quinidine
    • It is contraindicated to use this medicine if you have psychiatric disorders and seizures
    • Kindly avoid using this medicine if you have taken the antifungal medicine recently


    Zentrom 250mg Injection Side Effects

    • Anemia
    • Increased transaminase
    • Thrombocytopenia
    • Hyperbilirubinemia
    • Leukocytosis
    • Elevated creatinine
    • Pulmonary edema
    • Diarrhea
    • Jaundice
    • Neurologic sequelae


    FAQs for Zentrom 250mg Injection

    • Can I continue to take Zentrom 250mg Injection if I still don’t test negative for malaria?

    No, you should take the medicine as per the dose and duration prescribed by your doctor. If you feel feverish even after you finish the course kindly consult with your doctor.

    • Can I use Zentrom 250mg Injection for preventing malaria?

    No, the tablet is used to treat only uncomplicated malaria which is caused by Plasmodium falciparum.

    • Can I stop taking Zentrom 250mg Injection when I feel better?

    No, without consulting with a doctor you should not withdraw the medicine even if you feel better.


    Precautions and general warning of Zentrom 250mg Injection

    Alcohol

    It is not clear that consuming alcohol is safe while you are receiving this medicine. Kindly consult with your doctor.

    Driving or operating machinery

    It is considered unsafe to drive while you are receiving this medicine it may affect your ability to drive. Kindly consult with your doctor.

    Pregnancy

    The use of this medicine is considered unsafe during pregnancy because it may produce any harmful effects on the fetus. Kindly consult with your doctor

    Breast Feeding

    Limited information is available regarding the use of this medicine during breastfeeding. Kindly consult with your doctor.

    Kidney Problem

    Limited information is available regarding the use of this medicine in patients who are having a renal impairment. Kindly consult with your doctor.

    Liver Disease

    Limited information is available regarding the use of this medicine in patients who are having a hepatic impairment. Kindly consult with your doctor.


    How to Take Zentrom 250mg Injection

    Zentrom 250mg Injection comes in an liquid dosage form and shakes well before use. It is injected by a health care professional in doctor clinics, hospitals. Use the injection as prescribed by your doctor. Do not discontinue the medicine when you feel better kindly consult together with your doctor.


    Use of Zentrom 250mg Injection in Adult

    It is considered to be safe to use this medicine in an adult patient if the drug is prescribed by a doctor. Kindly consult with your doctor.


    Use of Zentrom 250mg Injection in children

    It is considered unsafe to use this medicine in children who are below 6 months old. Kindly consult with your doctor.


    Use of Zentrom 250mg Injection in Elderly Patients

    Zentrom 250mg Injection should be used with caution in patients with an elderly age group, which leads to developing further medical problems, leads to worsening the patient's health conditions. Kindly consult with your doctor. Dose modification or replacement is required based on the medical conditions of the patient.


    Other general warnings

    • The use of this medicine may cause hypotension, dyspnea, urticaria, or generalized rash
    • Post-artesunate delayed hemolysis is characterized by a decrease in the level of hemoglobin and leads to cause hemolytic anemia

                 Drug resistance

    • You may develop resistance to the drug if you withdraw the drug without completing the full course of treatment.


    Talk to your doctor if

    • You have a history of gastrointestinal disease
    • You are not responding to the treatment
    • You have experienced any allergic reaction like rashes and itching
    • You are having a concomitant disease or taking any medications


    General instructions

    Zentrom 250mg Injection consist of Artesunate 250mg is used to treat Malaria diseases (caused by Plasmodium falciparum strains of malarial parasite).

    Artesunate 250mg is an antimalarial drug, particularly used to treat malaria disease (resistant to other antimalarial medicines). Also, used to treat uncomplicated malaria disease with a combination of other antimalarial medicines.


    Drug Interaction of Zentrom 250mg Injection

    Drug-Drug Interaction

    Tepotinib

    Use alternative drugs because the use of sotorasib will decrease the effect of artesunate by P-glycoprotein efflux transporter.

    Carbamazepine
    Therapy should be administered with caution because the use of carbamazepine will decrease the effect of artesunate by increasing its metabolism.

    Diclofenac

    Therapy should be administered with caution because the use of diclofenac will increase the effect of diclofenac by decreasing its metabolism.

    Efavirenz

    It is a non-nucleoside reverse transcriptase inhibitor (NNRTIs) used to treat HIV infection. Zentrom 250mg injection (Artesunate) alters the action of efavirenz

    Drug-Food Interaction

    Food may increase the effect of this medicine on your body. So take the medicine as soon you complete your meal.

    Drug-Disease Interaction

    Liver diseases

    Zentrom 250mg injection (Artesunate) should be used with caution in a patient with hepatic impairment or liver diseases. Then it leads to the risk of liver damage. Based on the patient clinical conditions, dose adjustment or replacement is needed.

    Kidney diseases

    Zentrom 250mg injection (Artesunate) should be used with caution in a patient with renal impairment or kidney diseases. Then it leads to the risk of kidney damage. Based on the patient clinical conditions, dose adjustment or replacement is needed.

    Hematological toxicity

    Therapy should be used with caution in patients with hematological toxicity (leads to developing anemia, leukemia, thrombocytopenia, etc.), which leads to worsening the patient's health conditions. Based on the patient's health conditions, dose adjustment, or replacement is needed.


    Over Dose

    Take the medicine as directed by the doctor don’t overdose on the medicine. If you have taken an overdose of this medicine immediately meet the doctor and rush to the nearby hospital.


    Missed Dose

    Take the medicine as directed by the doctor. Do not skip the medicine, if you forgot to take the medicine or missed the dose. It is almost time for your next dose, skip the missed dose and go back to your regular schedule. Don’t take the extra dose take the regular dose immediately. Don’t use the two-dose at one time (Double Dose).


    Storage and Disposal

    • Stored at 10-30°C room temperature.
    • Protect from light and heat.
    • Keep away from children and pets. Otherwise, it becomes toxic to them.
    • Disposed of properly in a suitable bag.

     


    Fast Tag

    Zentrom 250mg Injection contains Artesunate 250mg used to treat malaria. Artesunate 250mg is an antimalarial drug, results in interacting with certain substances (required for vital functions of the malarial parasite cell) present in the blood. Then it eradicates the malarial infection caused by Plasmodium falciparum strains of malarial parasite. It is particularly used to treat malaria disease (resistant to other antimalarial medicines). Also, used to treat uncomplicated malaria disease with a combination of other antimalarial medicines.