Zepdon 400mg Tablet
Brand Name | Zepdon 400mg Tablet |
Salt Composition |
Raltegravir (400mg) |
Strength | 400mg |
Product Form | Tablet |
Pack | 60 Tablet(s) in 1 Bottle |
Storage | Store below 30°C |
Category |
HIV |
SubCategory |
HIV |
Country of Origin | India |
Manufacturer |
Cipla Ltd |
Manufacturer/Marketer Address | Cipla Ltd,Cipla House, Peninsula Business Park, Ganpatrao Kadam Marg, Lower Parel, Mumbai-400013. |
You Save : Rs.913.44 Inclusive of all taxes
- if you are allergic to Zepdon (Raltegravir (400mg)) tablet
- if you are lactating
- if you are pregnant
- if you have renal diseases like phenylketonuria
- if you have mental disorders
- if you are diabetic
- if you have liver diseases
- Skin reactions - It can be mild to severe like Stevens-Johnson Syndrome and toxic epidermal necrolysis.
- New onset diabetes mellitus or hyperglycemia – Monitor blood glucose and insulin levels.
- Immune reconstitution syndrome
- Lactic acidosis
- Rhabdomyolysis and myopathy
- Liver disorders – used with caution in severe liver diseases. Consult a physician before use
- Kidney disorders – used with caution in severe kidney diseases. Consult a physician before use
- Cardiac disorders – used with caution in heart failure and MI. Consult a physician before use
- Respiratory disorders – used with caution in respiratory distress. Consult a physician before use
Medical Description of Zepdon 400mg Tablet
Zepdon Tablet contains Raltegravir 400mg. Zepdon (Raltegravir (400mg)) tablet is an antiviral medicine used in the treatment of HIV-1 infection. Zepdon tablet is an HIV-1 integrase inhibitor. Zepdon tablet is used in combination with other antivirals to treat HIV. Zepdon tablet is also used in treatment as post-exposure for occupational exposure to HIV therapy.
Zepdon 400mg Tablet Uses
Zepdon (Raltegravir (400mg)) tablet is used to treat adults and children above 2 years of age or weight class above 10 Kgs who are infected by HIV-1 infection. Zepdon tablet should be taken with other anti-HIV medications.
Zepdon 400mg Tablet Benefits
Zepdon (Raltegravir (400mg)) tablet is used to treat HIV-1 infection. Zepdon tablet is an HIV-1 integrase inhibitor. Zepdon tablet is not a cure for HIV infection, it helps manage and treat HIV. Zepdon tablet improves the immune system thus prevents co-infection and cancers. Zepdon tablet is not recommended for use in children less than 2 years of age or weight lesser than 10 Kgs due to the increased risk of serious side effects.
Zepdon 400mg Tablet Indication
Zepdon (Raltegravir (400mg)) tablet is indicated in the treatment of HIV-1 infection. Zepdon tablet is co-administered safely with other antivirals for HIV. Zepdon tablet is indicated in ages above 2 years of age or weight above 10Kgs. Caution is used in the case of diagnosed phenylketonuria.
Mechanism of action of Zepdon 400mg Tablet
Zepdon (Raltegravir (400mg)) tablet is an integrase inhibitor. Zepdon tablet acts as an inhibitor of HIV-1 catalytic activity. Thus inhibits the replication of the virus. Thus, in combination with other antivirals.
How Zepdon 400mg Tablet works
Zepdon (Raltegravir (400mg)) tablet is an HIV-1 integrase inhibitor. Zepdon tablet inhibits the action of HIV-1 viruses’ catalytic action, thereby preventing the formation of mature virus particles. Thus, controls HIV infection and improves immunity.
Zepdon 400mg Tablet Contraindication
Absolute contraindication:
Relative contraindication:
Zepdon 400mg Tablet Side Effects
Very common side effects that occur 1:10 patients: Rash, nausea, vomiting, abdominal pain, diarrhea, somnolence
common side effects that occur 1:100 patients: headache, insomnia, fatigue, dizziness, dyspepsia, and increased liver enzymes, Decreased levels of neutrophils
uncommon side effects that occur 1:1000 patients: rash, hair loss, hematuria, jaundice, osteonecrosis, severe allergic reaction, lactic acidosis
FAQs for Zepdon 400mg Tablet
Is Zepdon (Raltegravir (400mg)) tablet safe during pregnancy?
No, taking Zepdon tablet during pregnancy is not recommended. Consult your physician.
Can Zepdon tablet be taken while breastfeeding?
No, taking Zepdon tablet is not recommended during breastfeeding. Consult your physician.
Can Zepdon tablet be taken while alcohol consumption?
The interaction is unknown but this medication causes side effects. Thus, consult your physician.
Can I take a drive or operate heavy machineries while on Zepdon tablet?
This medication causes side effects thus caution is used while driving or operating machineries.
Can Zepdon tablet be taken as monotherapy for HIV?
No, Zepdon tablet is used with other antivirals that treat HIV infection
Precautions and general warning of Zepdon 400mg Tablet
Alcohol
Zepdon (Raltegravir (400mg)) tablet generally causes side effects thus it is advised not to be taken with alcohol. For further queries, consult your physician.
Driving or operating machinery
It is preferred to drive or operate heavy machinery with caution as Zepdon (Raltegravir (400mg)) tablet causes side effects. For further queries, consult your physician.
Pregnancy
The use of Zepdon (Raltegravir (400mg)) tablet is not recommended during pregnancy.
Breast Feeding
The use of Zepdon (Raltegravir (400mg)) tablet during breastfeeding is not recommended.
Kidney Problem
Like phenylketonuria – monitor function. For further queries, consult your physician.
Liver Disease
Like hepatitis B or C
Monitor liver function before and during therapy, especially in patients with other
How to Take Zepdon 400mg Tablet
Zepdon (Raltegravir (400mg)) tablet is taken orally without food for best result.
Zepdon tablet must be taken at the same time once a day as prescribed by your physician.
Zepdon tablet is always taken with other antivirals for treating HIV infection.
After therapy has been initiated, do not take more or less of Zepdon medicine than prescribed or stop taking it without your physicians’ approval. Skipping or changing Zepdon tablet dose without approval may cause the amount of the virus to increase making the infection more difficult to treat, or worsen side effects.
Use of Zepdon 400mg Tablet in Adult
If you are pregnant or breastfeeding inform your physician as they are not advisable.
The recommended dosage of Zepdon (Raltegravir (400mg)) tablet in HIV infection is 400mg taken orally twice per day
Zepdon tablet must be taken with other antivirals as prescribed by the physician without fail. These medicines must be taken with or without food on a regular time basis.
Use of Zepdon 400mg Tablet in children
Zepdon (Raltegravir (400mg)) tablet must be taken with other antivirals as prescribed by the physician without fail. These medicines must be taken with or without food on a regular time basis.
Use of Zepdon 400mg Tablet in Elderly Patients
Zepdon (Raltegravir (400mg)) tablet has only been used in few patients 65 years or older. Dosage and usage are similar to adults. Discuss with your physician before usage.
Other general warnings
Talk to your doctor if
If you have any allergy
If you have a liver problem
If you have a kidney problem
If you are diabetic
If you are pregnant or breastfeeding
General instructions
Zepdon (Raltegravir (400mg)) tablet is taken orally with or without food as prescribed dosage at a specific time regularly. It can be safely used in cases of HIV cases who are on a regime
Drug Interaction of Zepdon 400mg Tablet
Drug-Drug Interaction
Side Effects are increased by Atorvastatin, Ciprofloxacin, Ivermectin, Montelukast
Serum concentration is decreased by Calcium carbonate, Ferrous, Zinc
Absorption is increased by aluminium hydroxide, esmoprazole, ranitidine
Drug-Food Interaction
Zepdon (Raltegravir (400mg)) tablet can be safely taken with any type of food, if doubts arise kindly refer to your physician. It generally causes side effects thus it is advised not to be taken with alcohol.
Drug-Disease Interaction
Over Dose
Contact your doctor, pharmacist or nurse immediately.
Missed Dose
If you take once a day dosage, then the missed dosage if you notice within 12 hours. If it is more than 12 hours, then skip the dosage and take the next doses as usual. If you take twice a day dosage, then the missed dosage if you notice within 6 hours. If it is more than 6 hours, then skip the dosage and take the next doses as usual. Always take with other antivirals Don’t take a double dose for a forgotten dose.
Storage and Disposal
Keep the medication out of children’s reach
Keep the medication away from pets
Once expired dispose immediately
Store at 30?C
Fast Tag
Zepdon (Raltegravir (400mg)) tabletcontains Raltegravir.
Zepdon tablet is an integrase inhibitor.
Zepdon tablet is used to control and treat HIV infection
Do not use this medication while the lactation period.
Don’t use this medication with liver disease and kidney diseases.
This medication doesn’t stop the spread of HIV infection from person to person thus use caution and precaution while sexual contact, needle injury etc.