Zithium O Suspension

Brand Name Zithium O Suspension
Salt Composition

Azithromycin (125mg) + Ofloxacin (50mg)

Strength 125mg + 50mg
Product Form Suspension
Pack 1 x 30ml in 1 Bottle
Storage Store below 30°C
Category

Antibiotic

SubCategory

Anti-Biotic

Country of Origin India
Manufacturer

Alkem Laboratories Limited

Manufacturer/Marketer Address Alkem Laboratories Limited, Devashish Building, Alkem House, Senapati Bapat Road, Lower Parel, Mumbai - 400 013.
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Availability : In Stock

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    Medical Description of Zithium O Suspension

    Zithium O Suspension contains Azithromycin 125mg and Ofloxacin 50mg used to treat bacterial infections such as Community-acquired pneumonia, Pharyngitis or Tonsillitis, Uncomplicated skin and skin structure, Acute bacterial exacerbations of chronic obstructive pulmonary diseases, Acute bacterial sinusitis, Genital Ulcer diseases, Gonorrhea, Pelvic inflammatory diseases. Azithromycin 125mg is a macrolide antibiotic that works by inhibiting the cell wall synthesis of protein. Ofloxacin 50mg is an antibiotic that helps to inhibit the growth of infection. Swallow the whole tablet at once. The combination of this medicine targets the respiratory tract, ear, nose, throat, lungs, skin, and eye in both adults and children and it is also used to treat typhoid fever.


    Zithium O Suspension Uses

    It is used in the treatment of the following conditions as Bacterial infections such as Community-acquired pneumonia, Pharyngitis or Tonsillitis, Uncomplicated skin and skin structure, Acute bacterial exacerbations of chronic obstructive pulmonary diseases, Acute bacterial sinusitis, Genital Ulcer diseases, Gonorrhea, Pelvic inflammatory diseases


    Zithium O Suspension Benefits

    Bacterial infections

    Bacterial infection occurs when bacteria enter your body and start multiplying which may cause tissue damage and make you sick. Mostly it is caused by Staphylococcus and Streptococcus organisms. The bacterial diseases are cholera, bacterial meningitis, tetanus, gonorrhea, pneumonia, and syphilis. Symptoms include fever, chills, and sweats, inflamed lymph nodes, headache, diarrhea, abdominal pain

     Urethritis and cervicitis in adults

    Azithromycin helps relieve the discharge and irritation in the cervix and urethral passage by its bacterial action.

    Acute exacerbations of chronic bronchitis in adults 

    In case of acute lung infection like bronchitis, inflammatory symptoms like cough and productive mucus are controlled effectively by the use of Azithromycin

    skin structure infections in adults 

    Bacterial skin infections can be better reduced by the use of azithromycin. it broadly reduces the inflammatory raches and itching caused by disease.

     Acute otitis media in pediatric patients

    The severe painful ear infections in the middle ear of children especially are relieved by Azithromycin. It can reduce the pain and inflammation caused by bacterial infection of the middle ear.

      Acute bacterial sinusitis in adults

    Sinusitis from bacterial origin can be well managed with the help of azithromycin. it reduces the troubling symptoms of sinus pains, fever, and postnasal discharge.

     Genital ulcer disease in men 

    The genital disease of men which are due to secondary bacterial diseases which gives rise to sore ulcers can be best treated with azithromycin.

     Community-acquired pneumonia in adults 

    The fast pace pathology of Community-acquired pneumonia from bacterial infections can be controlled with the use of Azithromycin. It reduces fever, heavy sputum, and shortness of breath.

    Gonorrhea

    It is a sexually transmitted infection caused by bacteria called Neisseria gonorrhoeae. It affects both males and females. Symptoms include thick discharge from the penis, increased vaginal discharge, pain while urinating, anal itching, discharge, and spotting between menstrual bleeding.


    Zithium O Suspension Indication

    Zithium O Suspension is prescribed in the following indications such Bacterial infections, Community-acquired pneumonia, Pharyngitis or Tonsillitis, Uncomplicated skin and skin structure, Acute bacterial exacerbations of chronic obstructive pulmonary diseases, Acute bacterial sinusitis, Genital Ulcer diseases, Gonorrhea, Pelvic inflammatory diseases


    Mechanism of action of Zithium O Suspension

    Zithium O Suspension contains Azithromycin 125mg and Ofloxacin 50mg it is a combination of two medicines. Azithromycin is a macrolide antibiotic used to treat bacterial infections. It stops bacterial growth by preventing the synthesis of essential proteins required by bacteria to carry out vital functions. Ofloxacin is a quinolone antibiotic that produces its action by inhibiting the activity of a bacterial enzyme called DNA gyrase and preventing the bacterial cell from reproduction and repairing themselves and killing the bacteria which is responsible for the infection.


    How Zithium O Suspension works

    Zithium O Suspension contains Azithromycin 125mg and Ofloxacin 50mg it is a combination of two medicines. Azithromycin is a macrolide antibiotic used to treat bacterial infections. It stops bacterial growth by preventing the synthesis of essential proteins required by bacteria to carry out vital functions. Ofloxacin is a quinolone antibiotic that produces its action by inhibiting the activity of a bacterial enzyme called DNA gyrase and preventing the bacterial cell from reproduction and repairing themselves and killing the bacteria which is responsible for the infection.


    Zithium O Suspension Contraindication

    • Do not take this medicine if you are allergic to Azithromycin and Ofloxacin
    • It is contraindicated to use this medicine in patients who are having a history of cholestatic jaundice and hepatic dysfunctions associated with the use of this medicine
    • The use of these medicines associated with side effects include tendinitis, tendon rupture, peripheral neuropathy, and the central nervous system effects
    • It is contraindicated to use this medicine in patients who are having a history of myasthenia gravis


    Zithium O Suspension Side Effects

    • Abdominal pain 
    • Nausea
    • Vomiting
    • Stomach upset
    • Loose stools, B
    • Blurred vision,
    • Irregular heartbeat
    • Pancreatitis
    • Fainting


    FAQs for Zithium O Suspension

    • How long should I take the Zithium O Suspension?

    Normally the duration of this medicine depends upon the severity of the disease. You should take this according to your doctor advice

    • Is the Zithium O Suspension is safe?

    Yes, it is considered safe when you have taken the medication as per the dose and duration advised by the doctor. If you stop the medicine without completing the course of treatment it may worsen the conditions

    • Can the use of Zithium O Suspension cause diarrhea?

    Yes, the use of this medicine may cause diarrhea since it is an antibiotic it affects both harmful and good bacteria which leads to cause diarrhea. Kindly consult with your doctor if your symptoms get worsen.


    Precautions and general warning of Zithium O Suspension

    Alcohol

    Consuming alcohol is considered unsafe while you are receiving this treatment. Kindly consult with your doctor.

    Driving or operating machinery

    No, Consuming this medicine will not affect your ability to drive. Kindly consult with your doctor.

    Pregnancy

    The use of this medicine is considered unsafe during pregnancy because it may produce any harmful effects. Kindly consult with your doctor

    Breast Feeding

    The use of this medicine is considered unsafe during breastfeeding because it may excrete via breastmilk. Kindly consult with your doctor

    Kidney Problem

    The medicine should be used with caution in patients with renal impairment. The use of this medicine required dose modification. Kindly consult with your doctor.

    Liver Disease

    The medicine should be used with caution in patients with severe liver impairment. The use of this medicine required dose modification. Kindly consult with your doctor.


    How to Take Zithium O Suspension

    The Zithium O Suspension is taken orally with or without food. You can measure the dose with the help of a measuring cup and shake well before using this Suspension. Follow the direction mentioned within the label if you probably did not understand the appliance kindly ask your doctor or pharmacist to elucidate in detail. Do not withdraw the medicine when you feel better kindly complete the course of treatment to avoid reoccurrence.


    Use of Zithium O Suspension in Adult

    It is considered to be safe to use this medicine in an adult patient if the medicine is prescribed by a doctor. Kindly consult with your doctor.


    Use of Zithium O Suspension in children

    Zithium O Suspension is not prescribed in children who are below 6 months old. Kindly consult with your doctor.


    Use of Zithium O Suspension in Elderly Patients

    Zithium O Suspension should be used with caution in patients with an elderly age group, which leads to developing further medical problems, leads to worsening the patient's health conditions. Kindly consult with your doctor. Dose modification or replacement is required based on the medical conditions of the patient.


    Other general warnings

    • The use of this medicine may cause abnormal liver function, hepatitis, cholestatic jaundice, hepatic necrosis, and hepatic failure.
    • Infantile hypertrophic pyloric stenosis was reported while you are using this medicine
    • Long-term use may cause bacterial or fungal overgrowth
    • Clostridium difficile associated diarrhea has been reported
    • Kindly avoid this medicine if you did not have a suspected bacterial infection this will increase the risk of developing drug-resistant bacteria.
    • The use of this medicine may cause QT prolongation which increases the risk of developing cardiac arrhythmia
    • The use of this medicine may cause hepatotoxicity and peripheral neuropathy
    • You may develop fatal hypoglycemia in elderly people who are with or without diabetes
    • Avoid sunlight because the use of this medicine can cause photosensitivity
    • There is an increased risk for developing fluoroquinolone associated tendinitis and tendon rupture in patients who are over 60 years of age
    • Convulsions increased intracranial pressure, and toxic psychosis was reported while you are using fluoroquinolones


    Talk to your doctor if

    • You have a history of gastrointestinal disease
    • You are not responding to the treatment
    • You have experienced any allergic reaction like rashes and itching


    General instructions

    Zithium O Suspension is a regular antibiotic against bacterial infections. particularly used for acute respiratory conditions, ear pains, surgical conditions, skin and soft tissue infections, genital sores. It helps in immediate action to relieve symptoms like fever and [ain. It helps in lung infections with severe pathology. Do not overdose on the tablet and take it according to the prescribed format. Before taking Azithromycin precautions to be taken if having any allergy history cardiac or kidney disease.


    Drug Interaction of Zithium O Suspension

    Drug-Drug Interaction

    BCG vaccine live

    The use of this medicine is contraindicated because the use of medicine decreases the effect of the BCG vaccine live by pharmacodynamic antagonism

    Cholera vaccine

    Use alternative medicine, because the use of the cholera vaccine with antibiotics may activate the vaccine strain. So, avoid receiving this combination of medicines before 14 days of vaccination

    Antithrombin 111

    Use alternative drugs because the use of azithromycin increases the effect of azithromycin by decreasing its metabolism.

    Digoxin

    Use alternative drugs because the use of azithromycin increases the effect of digoxin by altering the intestinal flora

    Aluminum hydroxide

    Use alternative drugs because the use of aluminum hydroxide decreases the effect of Ofloxacin by inhibiting the GI absorption

    Escitalopram

    Therapy should be administered with caution because the use of escitalopram increase the toxicity of Ofloxacin by QTc interval

    Estradiol

    Therapy should be administered with caution because the use of Ofloxacin decreases the effect of estradiol by altering the intestinal flora and it also lowers the risk of contraceptive failure.

    Drug-Food Interaction

    No interaction was found while using this medicine

    Drug-Disease Interaction

    Colitis

    This medicine kills the good helpful bacteria in your stomach or intestine and causes diarrhea. This medicine should be used caution in patients with gastrointestinal disease, especially colitis (swelling of the colon inner lining). It leads to worsening the patient’s health condition.

    Myasthenia gravis

    Therapy should be administered with caution because the use of macrolide antibiotics trigger the symptoms of myasthenia gravis

    Liver disease

    Therapy should be administered with caution because the use of azithromycin may cause hepatotoxicities like abnormal liver function, hepatitis, cholestatic jaundice, necrosis, and hepatic failure.

    QT prolongation

    Therapy should be administered with caution in patients who are having a history of bradyarrhythmia, proarrhythmic like uncorrected hypokalemia, hypomagnesemia because the use of azithromycin itself may cause cardiac repolarization and QT interval.

    Central nervous system disorders

    Using this medicine is needs caution in patients with seizures, other central nervous system abnormalities, or fits. It causes hallucinations, anxiety, confusion, and restlessness, etc. Inform the doctor, then will do dose adjustment or replacement is needed. If necessary to take this medicine with seizure medications.


    Over Dose

    Take the medicine as directed by the doctor don’t overdose on the medicine. If you have taken an overdose of this medicine immediately meet the doctor and rush to the nearby hospital.


    Missed Dose

    Take the medicine as directed by the doctor. Do not skip the medicine, if you forgot to take the medicine or missed the dose. It is almost time for your next dose, skip the missed dose and go back to your regular schedule. Don’t take the extra dose take the regular dose immediately. Don’t use the two-dose at one time (Double Dose).


    Storage and Disposal

    • Stored at 10-30°C room temperature.
    • Protect from light and heat.
    • Keep away from children and pets. Otherwise, it becomes toxic to them.
    • Disposed of properly in a suitable bag.


    Fast Tag

    Zithium O Suspension contains Azithromycin 125mg and Ofloxacin 50mg used to treat bacterial infections such as Community-acquired pneumonia, Pharyngitis or Tonsillitis, Uncomplicated skin and skin structure, Acute bacterial exacerbations of chronic obstructive pulmonary diseases, Acute bacterial sinusitis, Genital Ulcer diseases, Gonorrhea, Pelvic inflammatory diseases. And is widely used in treating certain bacterial infections like sinusitis, ear pain, and pneumonia for children. It is found to be a macrolide-type antibiotic. Its basic function is to stop the synthesis of certain proteins needed by bacteria for its’s survival. Thus it stops the growth of bacteria and prevents infection.